Broad Institute

JANUARY 6, 2025

In 2023, the first CRISPR Cas9-based therapeutic, which is based on a design Zhang developed in 2015, was approved for clinical use to treat sickle cell disease. This and other molecular tools developed by Zhang have accelerated biomedical research worldwide. Lisa Yang and Hock E.

Medical Schools 138

Medical Schools Engineering Science Hospitals 138

Science Daily: Pharmacology News

JUNE 29, 2023

The groundbreaking detection of gravitational waves in 2015, caused by the coalescence of two black holes, opened a new window into the universe. Black holes, some of the most captivating entities in the cosmos, possess an immense gravitational pull so strong that not even light can escape.

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The Pharma Data

DECEMBER 2, 2020

2, 2020 — In adolescents and young adults (AYAs), cancer has a unique epidemiological pattern and is a growing concern, with an increased rate of cancer from 1973 to 2015, according to a study published online Dec. The study included 497,452 AYAs diagnosed with cancer from 1973 to 2015. WEDNESDAY, Dec. 1 in JAMA Network Open.

Research 52

Research 52

BioPharma Drive: Drug Pricing

JULY 20, 2023

The startup will take on development of a shigellosis vaccine GSK inherited when it acquired LimmaTech’s predecessor, GlycoVaxyn, in 2015.

Vaccine 130

Vaccine Licensing Licensing 130

New Drug Approvals

MAY 9, 2025

Standard of Care for the Treatment of Patients With ER+/HER2- Advanced Breast Cancer” at ClinicalTrials.gov ^ Jump up to: a b c Wardell SE, Nelson ER, Chao CA, Alley HM, McDonnell DP (October 2015). Jump up to: a b c Garner F, Shomali M, Paquin D, Lyttle CR, Hattersley G (October 2015). 22 (5): 713724. doi : 10.1530/ERC-15-0287.

FDA 64

FDA Pharmacokinetics Therapies Treatment 64

addgene Blog

JUNE 20, 2023

Since its introduction in 2015 by the Boyden Lab , ExM has been steadily growing in popularity with an abundance of protocols and examples of applications from across disciplines now available.

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SCIENMAG: Medicine & Health

AUGUST 18, 2023

The proportion of students reporting attention deficit hyperactivity disorder or chronic health and/or psychological disabilities has increased between 2015 and 2021. Medical students who reported a disability to their school increased by more than 25% during the COVID-19 pandemic, a study shows.

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Broad Institute

AUGUST 31, 2023

TBD By lcopelan@broadinstitute.org August 31, 2023 Yuhan Hao Neptune Bio Related Resources [link] MIA About Current Schedule Video Playlist Resources All talks Contact us MIA Talks Search - Any - Spring 2023 Fall 2022 Spring 2022 Fall 2021 Spring 2021 Fall 2020 Spring 2020 Fall 2019 Spring 2019 Fall 2018 Spring 2018 Fall 2017 Spring 2017 Fall 2016 (..)

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SCIENMAG: Medicine & Health

NOVEMBER 28, 2023

9, 2015, hangs just outside Nicole Hashemi’s Iowa State University laboratory. AMES, Iowa – A research poster dated Dec. It introduces a major project for Hashemi and her research group. And it’s evidence that scientific persistence sometimes equals scientific advancement. Credit: Photo by Christopher Gannon/Iowa State University.

Research 86

Research Laboratories 86

Fierce BioTech

JULY 17, 2023

As recently as 2015, researchers concluded that anywhere from 50-80% of pre-clinical animal (in vivo) research data was irreproducible,1 representing a monetary loss of more than $28 billion. PLOS Biology 13(6): e1002165.

Clinical Trials 88

Clinical Trials Drug Development Research Trials 88

FDA Law Blog: Biosimilars

MARCH 18, 2025

Merck applied for a patent term extension on the reissued patent, claiming the start of the regulatory review period as April 2004 and termination at the approval of the BRIDION NDA in December 2015. With this long regulatory review period, the PTO granted the statutory-maximum five-year patent term extension.

Pharmaceutical Companies 59

Pharmaceutical Companies FDA Production Regulations 59

SCIENMAG: Medicine & Health

DECEMBER 8, 2023

According to the World Health Organization (WHO), between 2015 and 2021, 48% of mothers exclusively breastfed, meaning that their babies were not given any other food or liquids. Exclusive breastfeeding for the first six months of life is proven to protect both mother and child health.

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SCIENMAG: Medicine & Health

NOVEMBER 17, 2023

A team of scientists from the Institut Pasteur has used the database of the National Reference Center for Meningococci to trace the evolution of invasive meningococcal disease cases in France between 2015 and 2022, revealing an unprecedented resurgence in the disease after the easing of control measures imposed during the COVID-19 epidemic.

Disease 76

Disease 76

Drug Target Review

OCTOBER 25, 2023

2015 March 3 [2022 December 15]; 2015(8):7-12. This research was published in JCI Insight. References 1 English FA, Kenny LC, McCarthy FP. Risk factors and effective management of preeclampsia. Dovepress [Internet]. Available from: [link]

Treatment 105

Treatment Virus Research Science 105

SCIENMAG: Medicine & Health

JULY 26, 2023

Royal colleges in the UK have received more than £9 million in marketing payments from drug and medical devices companies since 2015, but do not always disclose the payments publicly, finds an investigation published by The BMJ today.

Drugs 69

Drugs Marketing 69

Drug Channels

DECEMBER 16, 2022

Fortunately, my 2022 FOIA efforts (described below) extracted purchases by 340B covered entity type for 2015 through 2021. Shortly after I published the article below, HRSA posted public data about 340B covered entity purchases on its website. Alas, HRSA neglected to post any historical data.

Hospitals 97

Hospitals Drugs Pharmacy 97

Molecular Design

JULY 26, 2023

The odds against such an encounter would appear to be overwhelming since Ash lives in California while this was my first visit to the USA since 2015. Ash and I have actually known each other for about 15 years but we’d never before met in real life.

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SCIENMAG: Medicine & Health

AUGUST 27, 2023

Indigenous females living “off reserve” face many disparities in health care access, use and unmet needs, found new research in CMAJ (Canadian Medical Association Journal) [link] The study included 2902 First Nations, 2345 Métis, 742 Inuit and 74 760 non-Indigenous females of reproductive age (aged 15–55 years) obtained from the Canadian (..)

Research 66

Research 66

SCIENMAG: Medicine & Health

JULY 26, 2023

A key element of the 2015 Paris Agreement, a legally binding international treaty on climate change, is the commitment to limit average global temperatures increases to well below […]

International 63

International Research 63

Drug Target Review

NOVEMBER 6, 2023

2015);126(1):9-16. 2015);126(4):454-462. Clonal hematopoiesis of indeterminate potential and its distinction from myelodysplastic syndromes. Strati P, Shanafelt TD. Monoclonal B-cell lymphocytosis and early-stage chronic lymphocytic leukemia: diagnosis, natural history, and risk stratification.

Small Molecule 111

Small Molecule Therapies Treatment Disease 111

Reprocell

JULY 18, 2024

In April 2015, the 106 th annual meeting of the American Association for Cancer Research was held in Philadelphia, Pennsylvania. REPROCELL USA was in attendance and submitted a poster titled , Family History of Cancer in First-degree Relatives and Increased Cancer Risk: A Multinational Study.

Research 52

Research 52

The Pharma Data

JANUARY 15, 2021

Men aged 18 to 64 years undergoing vasectomy between 2007 and 2015 with at least 12 months of follow-up were identified. The researchers identified 87,201 patients who underwent vasectomy between 2007 and 2015 and had at least one postvasectomy semen analysis claim. and 0.82, respectively).

Research 52

Research 52

The Pharma Data

NOVEMBER 20, 2020

from University College London, and colleagues assessed changes in the prevalence of weight-control behaviors and weight perception between 1986 and 2015. The researchers found that in 2015, 44.4 The researchers found that in 2015, 44.4 Similarly, more were trying to lose weight in 2015 versus 2005 (42.2 to 1.66).

Research 52

Research 52

SCIENMAG: Medicine & Health

AUGUST 7, 2023

Founded in 2015, the Center is headquartered at DOE’s Argonne National Laboratory. Department of Energy (DOE) has announced the renewal of the Midwest Integrated Center for Computational Materials (MICCoM) for another three years at $3 million per year.

Laboratories 55

Laboratories 55

Broad Institute

OCTOBER 11, 2024

Large Language Models and Biological Foundation Models By lcopelan@broadinstitute.org October 11, 2024 Large Language Models and Biological Foundation Models Syed Rizvi Talks Search - Any - Fall 2024 Spring 2024 Fall 2023 Spring 2023 Fall 2022 Spring 2022 Fall 2021 Spring 2021 Fall 2020 Spring 2020 Fall 2019 Spring 2019 Fall 2018 Spring 2018 Fall 2017 (..)

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Broad Institute

AUGUST 30, 2024

Lightning Talks By lcopelan@broadinstitute.org August 30, 2024 Lightning Talks MIA About Current Schedule Video Playlist Resources All talks Contact us MIA Talks Search - Any - Fall 2024 Spring 2024 Fall 2023 Spring 2023 Fall 2022 Spring 2022 Fall 2021 Spring 2021 Fall 2020 Spring 2020 Fall 2019 Spring 2019 Fall 2018 Spring 2018 Fall 2017 Spring 2017 (..)

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Broad Institute

AUGUST 28, 2024

TBD By lcopelan@broadinstitute.org August 28, 2024 TBD Brian Cleary MIA About Current Schedule Video Playlist Resources All talks Contact us MIA Talks Search - Any - Fall 2024 Spring 2024 Fall 2023 Spring 2023 Fall 2022 Spring 2022 Fall 2021 Spring 2021 Fall 2020 Spring 2020 Fall 2019 Spring 2019 Fall 2018 Spring 2018 Fall 2017 Spring 2017 Fall 2016 (..)

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Broad Institute

AUGUST 22, 2024

TBD By lcopelan@broadinstitute.org August 22, 2024 TBD Abraham Gihawi MIA About Current Schedule Video Playlist Resources All talks Contact us MIA Talks Search - Any - Fall 2024 Spring 2024 Fall 2023 Spring 2023 Fall 2022 Spring 2022 Fall 2021 Spring 2021 Fall 2020 Spring 2020 Fall 2019 Spring 2019 Fall 2018 Spring 2018 Fall 2017 Spring 2017 Fall 2016 (..)

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Broad Institute

AUGUST 8, 2024

Microbiome By lcopelan@broadinstitute.org August 8, 2024 Microbiome Victoria Pascal MIA About Current Schedule Video Playlist Resources All talks Contact us MIA Talks Search - Any - Fall 2024 Spring 2024 Fall 2023 Spring 2023 Fall 2022 Spring 2022 Fall 2021 Spring 2021 Fall 2020 Spring 2020 Fall 2019 Spring 2019 Fall 2018 Spring 2018 Fall 2017 Spring (..)

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Broad Institute

AUGUST 8, 2024

Molecular dynamics By lcopelan@broadinstitute.org August 8, 2024 Molecular dynamics Ashkan Fakharzadeh Ghaan MIA About Current Schedule Video Playlist Resources All talks Contact us MIA Talks Search - Any - Fall 2024 Spring 2024 Fall 2023 Spring 2023 Fall 2022 Spring 2022 Fall 2021 Spring 2021 Fall 2020 Spring 2020 Fall 2019 Spring 2019 Fall 2018 Spring (..)

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Broad Institute

AUGUST 8, 2024

Tensor factorization + single-cell rna-seq By lcopelan@broadinstitute.org August 8, 2024 Tensor factorization + single-cell rna-seq Neriman Tokcan UMass Boston MIA About Current Schedule Video Playlist Resources All talks Contact us MIA Talks Search - Any - Fall 2024 Spring 2024 Fall 2023 Spring 2023 Fall 2022 Spring 2022 Fall 2021 Spring 2021 Fall (..)

RNA 40

RNA 40

Broad Institute

AUGUST 8, 2024

Single-cell genomics + LLM or OT By lcopelan@broadinstitute.org August 8, 2024 Single-cell genomics + LLM or OT David van Dijk Yale University MIA About Current Schedule Video Playlist Resources All talks Contact us MIA Talks Search - Any - Fall 2024 Spring 2024 Fall 2023 Spring 2023 Fall 2022 Spring 2022 Fall 2021 Spring 2021 Fall 2020 Spring 2020 (..)

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Broad Institute

SEPTEMBER 30, 2024

Talks Search - Any - Fall 2024 Spring 2024 Fall 2023 Spring 2023 Fall 2022 Spring 2022 Fall 2021 Spring 2021 Fall 2020 Spring 2020 Fall 2019 Spring 2019 Fall 2018 Spring 2018 Fall 2017 Spring 2017 Fall 2016 Spring 2016 Fall 2015 Summer 2015 Spring 2015 Spring 2014 Fall 2014

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The Pharma Data

NOVEMBER 9, 2020

drug approvals from 2015 to 2019 were outside the U.S., Almost two-thirds of participants in clinical trials to support U.S. the FDA’s Center for Drug Evaluation and Research (CDER) said in a new report unveiled yesterday. Source link.

Clinical Trials 52

Clinical Trials Trials Drugs Research 52

Drug Patent Watch

DECEMBER 10, 2024

.” – Association for Accessible Medicines References Examining the impact of biosimilar-to-biosimilar transition on healthcare costs. link] An inflection point for biosimilars. link] Biosimilars advancements: Moving on to the future. Biotechnology Progress, 31(4), 11391149. Harvard Kennedy School.

Biosimilars 96

Biosimilars Drugs Production Clinical Trials 96

Broad Institute

MAY 23, 2024

MIA About Current Schedule Video Playlist Resources All talks Contact us MIA Talks Search - Any - Spring 2024 Fall 2023 Spring 2023 Fall 2022 Spring 2022 Fall 2021 Spring 2021 Fall 2020 Spring 2020 Fall 2019 Spring 2019 Fall 2018 Spring 2018 Fall 2017 Spring 2017 Fall 2016 Spring 2016 Fall 2015 Summer 2015 Spring 2015 Spring 2014 Fall 2014

Medical Schools 45

Medical Schools Research Drugs 45

Drug Target Review

AUGUST 17, 2023

2015 Nov;268(1):104-22. 2015 Apr 13;27(4):473-88. To achieve this, the group is using innovative technologies, including a combination of advanced preclinical models of human cancers ( e.g., PDX, CDX, humanized) and complementary platforms ( e.g., syngeneic models, cell cultures), and novel reagents ( e.g., monoclonal antibodies).

International 98

International Therapies Regulations Clinical Trials 98