article thumbnail

What Makes a Mature Science

Codon

We need to help the Spinozas of bioinformatics grind out new lenses. They got very good at StarCraft 2 up to 2019, but still haven’t transcended the best human players. Tools like genetic sequencing made it possible to diagnose cancer based on mutations, rather than location, and made targeting of genetic diseases possible.

Science 79
article thumbnail

Advancing vaccine design: potential of peptide mimicry

Drug Target Review

Since December 2019, SARS-CoV-2 (COVID-19) infection has become a worldwide urgent public health concern. 1 The study reveals a novel bioinformatic approach and tool that holds the potential to empower researchers in designing vaccines capable of inducing a stronger immune response.

Vaccine 98
Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

article thumbnail

Biochemical assays and deep cyclic inhibition in cancer treatment

Drug Target Review

Using our bioinformatics expertise, we then map those profiles onto a large database of patient data – the AACR Project GENIE database – to translationally predict which tumour types are likely to be most responsive to monotherapy or combination therapy to our drug candidate.

article thumbnail

A scientist devotes her career to tackling inequity in genomics

Broad Institute

In 2019, they compared the scores’ performance across a wider range of populations, and showed how the scores were about half as likely to reliably predict disease among Hispanic/Latino Americans populations, South Asians, and East Asians as Europeans, and only one-fifth as likely to accurately predict them among African populations.

Disease 98
article thumbnail

Unlocking the potential of natural products in drug discovery

Drug Target Review

Her major focus has been untargeted metabolomics method development and bioinformatics solutions for structure elucidation. Natural products as sources of new drugs over the nearly four decades from 01/1981 to 09/2019. References Newman DJ, Cragg GM. Journal of Natural Products. 2020;83(3):770–803. doi:10.1021/acs.jnatprod.9b01285

article thumbnail

AI At The Frontier: Empowering Early Career Professionals In Drug Discovery

Elrig

With a background in Bioinformatics and Computational Biology, she has a keen interest in using technology to solve problems in healthcare and medicine. Driven by an interest in structural biochemistry and drug discovery (DD), I joined AstraZeneca in 2019. Bioinformatics is all about bringing together different areas of knowledge.

article thumbnail

Identify and Validate Innovative Peptides for the Treatment of Obesity

The Pharma Data

In 2019, Boehringer Ingelheim achieved net sales of 19 billion euros. Gubra experts cover a number of pre-clinical disciplines: in vivo pharmacology, peptide chemistry, molecular pharmacology, histology, 3D imaging, stereology, NGS (next generation sequencing), bioinformatics and ex vivo assays. Our significant investment of almost 3.5