Science Daily: Pharmacology News

SEPTEMBER 19, 2024

A new study provides a list of the wildlife species present at the market from which SARS-CoV-2, the virus responsible for the COVID-19 pandemic, most likely arose in late 2019. The study is based on a new analysis of metatranscriptomic data released by the Chinese Center for Disease Control and Prevention (CDC).

Marketing

New Drug Approvals

JULY 18, 2025

It was approved in China in 2021 as a first-in-class treatment for human immunodeficiency virus (HIV). 2020, 63, 8554−8566. (7) China Patent CN 111892636, 2020. 11] It is believed to work by inhibiting the RNA-dependent RNA polymerase (RdRp) enzyme in the SARS-CoV-2 virus. [12] 2024, 67, 4376−4418 Azvudine (1).

RNA

Broad Institute

JUNE 18, 2024

Simple test for flu could improve diagnosis and surveillance By Allessandra DiCorato June 18, 2024 Breadcrumb Home Simple test for flu could improve diagnosis and surveillance A low-cost CRISPR-based paper strip test distinguishes between influenza types and can be reprogrammed to recognize different viruses including the H5N1 bird flu virus.

Virus

The Pharma Data

DECEMBER 16, 2020

Most experts believe the SARS-CoV-2 virus originated in animals in China, probably bats, the Associated Press reported. Tracking down the animal in which the virus emerged will be key, so the group will take samples of further bat species and other animals that might harbor it, Leendertz added. © 2020 HealthDay. .

Virus

The Pharma Data

NOVEMBER 20, 2020

The curfew will be implemented in the 41 of the state’s 58 counties with the largest increases in virus cases, and will affect 94% of California’s nearly 40 million residents. © 2020 HealthDay. Posted: November 2020. We are sounding the alarm,” Gov. Gavin Newsom said in a statement. All rights reserved.

Virus

The Pharma Data

DECEMBER 29, 2020

Experts believe brain-related effects may be tied to the body’s immune response to the virus and possibly to vascular problems or surges of inflammation caused by the disease. WHO is working with scientists around the world to “better understand any and all changes to the virus” and their impact, he said.

Virus

The Pharma Data

DECEMBER 2, 2020

It’s not known if these infections were in people who caught the virus in other countries, or whether the infections led to wider community transmission, said the authors of the study that has been accepted for publication in the journal Clinical Infectious Diseases. © 2020 HealthDay. Posted: December 2020.

Virus

SCIENMAG: Medicine & Health

JANUARY 16, 2024

In early 2020, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a highly contagious and pathogenic virus, made its alarming debut and quickly spread worldwide, causing the novel coronavirus (COVID-19) pandemic that threatened human health and public safety.

Virus

Drug Target Review

AUGUST 11, 2023

In a new development, a recent paper published in Biology Methods & Protocols by Oxford University Press has highlighted a promising avenue for enhancing vaccine efficacy against infectious pathogens like the COVID-19 virus. The role of extracellular vesicles in COVID-19 virus infection [Internet]. Available from: [link]

Vaccine

The Pharma Data

OCTOBER 26, 2020

27, 2020 /PRNewswire/ — Aridis Pharmaceuticals, Inc. Dr. Hasan Jafri , Chief Medical Officer of Aridis Pharmaceuticals, will be a speaker on a panel entitled “Direct Antivirals and Other Agents Against SARS-CoV2 Virus.” SAN JOSE, Calif. , AR-711 (COVID-19). AR-201 (RSV infection). AR-201 (RSV infection).

Pharmaceuticals

The Pharma Data

NOVEMBER 13, 2020

A new survey shows one in five cancer patients are far less likely to participate in future clinical trials due to fear of COVID-19 exposure, raising the question of whether enrollment levels that have dropped precipitously since the beginning of the pandemic are likely to recover after the virus is controlled. percent since March 15.

Trials

The Pharma Data

OCTOBER 29, 2020

29, 2020– Alexion Pharmaceuticals, Inc. NASDAQ:ALXN) today announced financial results for the third quarter of 2020. Non-GAAP diluted EPS for the third quarter of 2020 was $3.24 , a 16 percent increase versus the third quarter of 2019. ” Third Quarter 2020 Financial Highlights. in the prior year.

Clinical Trials

The Pharma Data

OCTOBER 21, 2020

22, 2020 (GLOBE NEWSWIRE) — Replimune Group, Inc. The offering is expected to close on October 26, 2020, subject to the satisfaction of customary closing conditions. BOSTON, Oct. Morgan Securities LLC, SVB Leerink LLC and Barclays Capital Inc. are acting as joint book-running managers for the offering.

Immune Response

The Pharma Data

MAY 6, 2021

This donation of the vaccine is another tool in our toolbox of measures to help make the Olympic and Paralympic Games Tokyo 2020 safe and secure for all participants and to show solidarity with our gracious Japanese hosts,” said IOC President Thomas Bach. “We This press release features multimedia. View the full release here: [link].

Vaccine

The Pharma Data

NOVEMBER 10, 2020

S is derived from a common cold virus that is modified to carry a gene from the SARS-CoV-2 virus which causes COVID-19, prompting the immune system to develop resistance to the virus.

Vaccine

NIH Director's Blog: Drug Discovery

NOVEMBER 5, 2020

Because SARS-CoV-2 is so highly infectious, basic researchers without access to specially designed biosafety facilities may be limited in their ability to study the virus. While the quantum dots may bind and enter human cells just like the virus, they can’t cause an infection. 2020 Sep 22;14(9):12234-12247.

Research Laboratories

The Pharma Data

JANUARY 6, 2021

The announcement, following a $98 million IPO in October 2020, comes as the company advances several programs through its pipeline. In addition to its lead program, which began Phase I testing in 2020, the company expects to nominate three clinical candidates in 2021.

Virus

The Pharma Data

DECEMBER 9, 2020

10, 2020 04:32 UTC. The offering is expected to close on or about December 14, 2020, subject to satisfaction of customary closing conditions. Rocket’s first clinical program using adeno-associated virus (AAV)-based gene therapy is for Danon disease, a devastating, pediatric heart failure condition. Forward-looking Statements.

Pharmaceuticals

The Pharma Data

DECEMBER 16, 2020

16, 2020 — A World Health Organization team of experts will examine samples and medical data from China to try to find out where the new coronavirus first made the leap from animals to people. © 2020 HealthDay. . © 2020 HealthDay. Posted: December 2020. WHO Team Seeks to Pinpoint Source of COVID-19. WEDNESDAY, Dec.

Virus

The Pharma Data

DECEMBER 23, 2020

23, 2020 — A COVID-19 outbreak in Antarctica means that the new coronavirus is now spreading on every continent. Until then, Antarctica had been the only continent that was free of the virus, CNN reported. © 2020 HealthDay. Posted: December 2020. WEDNESDAY, Dec. CNN Article. All rights reserved. More News Resources.

Virus

The Pharma Data

DECEMBER 15, 2020

15, 2020 — The U.S. Preventive Services Task Force (USPSTF) concludes that screening adults and adolescents at increased risk for hepatitis B virus (HBV) infection has moderate net benefit. © 2020 HealthDay. Posted: December 2020. Professional. USPSTF Recommends Hep B Screen for At-Risk Teens, Adults. TUESDAY, Dec.

Virus

The Pharma Data

DECEMBER 17, 2020

17, 2020 — As a rule, COVID-19 spreads rapidly in most groups, but new research suggests that schools and day care centers appear to be the exception. ” But for schools to be safe, they need a lot of help, support and equipment to keep the virus from spreading, Hobbs said. © 2020 HealthDay. . © 2020 HealthDay.

Virus

The Pharma Data

OCTOBER 27, 2020

27, 2020 — The tiny droplets that linger in the air after people talk, cough or sneeze aren’t very efficient at spreading the new coronavirus , new research suggests. © 2020 HealthDay. Posted: October 2020. TUESDAY, Oct. It is even lower if that person was only talking. And wash your hands.” Source link.

Virus

The Pharma Data

DECEMBER 28, 2020

28, 2020 — Travelers flying to the United States from the United Kingdom will now need a negative COVID-19 test no more than 72 hours before leaving Britain, the U.S. The test is needed to guard against the spread of a new form of the virus found in the United Kingdom that may be 70 percent more contagious than other forms of COVID-19.

Virus

The Pharma Data

NOVEMBER 18, 2020

18, 2020 — The Ebola outbreak in the Democratic Republic of the Congo (DRC) is over, health officials say. © 2020 HealthDay. Posted: November 2020. Ebola Outbreak in Democratic Republic of the Congo Declared Over. WEDNESDAY, Nov. More Information. All rights reserved. More News Resources. Subscribe to our Newsletter.

Virus

The Pharma Data

DECEMBER 23, 2020

While the overall understanding of the condition is as novel as the virus that causes it, a recent survey from the U.K.’s This is proving very difficult, however, for the ever-expanding group of people dealing with the chronic and debilitating symptoms of what is commonly being called “Long Haul COVID” or “Long COVID.”.

Clinical Trials

The Pharma Data

JUNE 25, 2021

The outcome confirms that only one single case was attributable to the original SARS-CoV-2 virus. “In addition, the variant-rich environment underlines the importance of developing next-generation vaccines as new virus variants continue to emerge.” More than half of the cases (57%) were caused by Variants of Concern.

Vaccine

The Pharma Data

NOVEMBER 23, 2020

23, 2020 — On Monday, AstraZeneca announced that late-stage clinical trials of its COVID-19 vaccine showed it to be 70.4 © 2020 HealthDay. Posted: November 2020. Professional. Third COVID-19 Vaccine Shows Effectiveness. MONDAY, Nov. percent effective, The New York Times reported. The New York Times Article.

Vaccine

The Pharma Data

OCTOBER 23, 2020

ANESTHESIOLOGY 2020. The authors evaluated COVID-19 testing results (using a polymerase chain reaction [PCR] test and a verbal screening method) performed prior to anesthesia procedures among 1,033 children between March 26 and May 11, 2020. © 2020 HealthDay. Posted: October 2020. ” Press Release. . THURSDAY, Oct.

Virus

Molecular Design

AUGUST 9, 2020

> I sometimes wonder what percentage of the pharmacopoeia will have been proposed for repurposing for the treatment of COVID19 by the end of 2020. There are three general approaches to directly tackle a virus such as SARS-CoV-2 with a small molecule drug (or chemical agent).

Drugs

The Pharma Data

DECEMBER 2, 2020

3, 2020 09:00 UTC. MTX-COVAB was also found to have virus neutralizing potency (IC50= 40pM), which is comparable or better to that of the leading antibody therapies in development, and cross-neutralizes all clinically relevant virus mutants. About Memo Therapeutics AG.

Disease

The Pharma Data

DECEMBER 14, 2020

Date: 7 December 2020 . WHO-identifier: 2020/5, version 1. The design principle of RT-PCR means that for patients with high levels of circulating virus (viral load), relatively few cycles will be needed to detect virus and so the Ct value will be low.

Virus

The Pharma Data

DECEMBER 28, 2020

28, 2020 — The World Health Organization says steps to expand genome sequencing of new variants of the coronavirus are needed as the pandemic enters its second year, the Associated Press reported. © 2020 HealthDay. Posted: December 2020. Professional. WHO Calls for New Measures to Identify COVID-19 Variants. MONDAY, Dec.

Virus

The Pharma Data

OCTOBER 28, 2020

28, 2020 /PRNewswire/ — . In the overall patient group with detectable virus at baseline, the average daily reduction in viral load through day 7 was a 0.36 Securities and Exchange Commission, including its Form 10-K for the year ended December 31, 2019 and its Form 10-Q for the quarterly period ended June 30, 2020.

Virus

The Pharma Data

NOVEMBER 10, 2020

He said the company will potentially supply 76 million doses of the plant-based vaccine, which uses noninfectious virus-like particles to mimic the coronavirus in order to induce an immune response. The interim analysis from the phase 1 trial has been published online at the preprint server, medRxiv. Martin Berman-Gorvine.

Immune Response

The Pharma Data

DECEMBER 23, 2020

23, 2020 — Keep your distance. “A mask definitely helps, but if the people are very close to each other, there is still a chance of spreading or contracting the virus,” said study co-author Krishna Kota, an associate professor of mechanical and aerospace engineering. © 2020 HealthDay. Posted: December 2020.

Virus

The Pharma Data

OCTOBER 15, 2020

15, 2020 — A single pick-up hockey game in Tampa Bay in June wound up becoming a COVID-19 superspreader event, with one player infecting as many as 15 other people on the ice, Florida public health officials report. © 2020 HealthDay. Posted: October 2020. THURSDAY, Oct. The other two sick people were not tested for COVID.

Virus