Drug Target Review

JUNE 5, 2025

5,6 The 2023 approval of two engineered stem cell-based therapies marked a significant advancement, though these options require careful consideration of potential adverse events and long-term safety, 7 and access will remain a challenge for the foreseeable future. JAMA Network Open. 2023;6(11) Newman TV, Yang J, Haubner A, et al.

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Drug Target Review

NOVEMBER 7, 2024

These antibodies are engineered to bind to specific cell-surface receptors in a multivalent manner, effectively cross-linking and clustering receptor complexes upon binding. Nat Rev Immunol 21, 680–686 (2021). Therap Adv Gastroenterol. 2022 Nov 29; 15:17562848221138160. 4 McInnes IB, Gravallese EM.

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Codon

NOVEMBER 1, 2024

More specifically, it reveals that the price to sequence a human genome fell from $100 million in 2001 to $700 by 2021; a stunning collapse in price. The world’s supply of insulin is now made by engineered microbes. The cost of sequencing a human genome.

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The Strateos Blog: Drug Discovery

DECEMBER 13, 2021

SynBioBeta 2021 – the Global Synthetic Biology Conference – will take place between January 25th - 27th 2022 in Oakland, California. Senior Director, R&D Strategy, will be delivering a presentation highlighting how Strateos' smart lab platform accelerated riboswitch engineering to develop novel biosensors.

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Broad Institute

MAY 14, 2025

Cas9 ancestor engineered into a compact genome editing tool By Tom Ulrich May 14, 2025 Breadcrumb Home Cas9 ancestor engineered into a compact genome editing tool Researchers adapt a compact RNA-guided enzyme from bacteria for a variety of DNA editing tasks in human cells.

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Engineering DNA RNA Therapies 59

Broad Institute

JUNE 10, 2024

This system, called eePASSIGE, can make gene-sized edits several times more efficiently than other similar methods, and is reported today in Nature Biomedical Engineering. “To Nature Biomedical Engineering. We hope this system will prove to be an important step towards realizing the benefits of targeted gene integration for patients.”

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The Pharma Data

DECEMBER 1, 2020

02, 2020 (GLOBE NEWSWIRE) — Innate Pharma SA (Euronext Paris: IPH – ISIN: FR0010331421; Nasdaq: IPHA) (“ Innate ” or the “ Company ”) today released its 2021 financial calendar: March 18, 2021: Publication of 2020 financial statements. MARSEILLE, France, Dec. . .

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Cell Biology Clinical Trials Production Licensing 52

The Pharma Data

SEPTEMBER 14, 2020

Call for Award Applicants: Johnson & Johnson Seeks Female Researchers Working in Science, Technology, Engineering, Math, Manufacturing and Design. Call for Award Applicants: Johnson & Johnson Seeks Female Researchers Working in Science, Technology, Engineering, Math, Manufacturing and Design.

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The Pharma Data

JANUARY 7, 2021

With eight drugs awaiting regulatory approval and 26 projects in Phase III studies, Sanofi is on the cusp of a transformative year during 2021. That platform will allow the company to engineer new proteins, Nestle said. ricochet64/Shutterstock. That was the message the company shared during a pre-J.P. billion acquisition of Synthorx.

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Disease Therapies Engineering Treatment 52

The Pharma Data

JANUARY 25, 2021

26, 2021 10:00 UTC. has been awarded the 2021 Jeantet-Collen Prize for Translational Medicine. has been awarded the 2021 Jeantet-Collen Prize for Translational Medicine. NEW YORK & AMSTERDAM–( BUSINESS WIRE )– Neogene Therapeutics, Inc. , President, Chief Executive Officer and Co-Founder of Neogene Therapeutics.

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The Pharma Data

JULY 6, 2021

Sanofi highlights scientific innovations in the field of rare blood disorders at I STH 2021. It is engineered by fusing factor VIII to the Fc portion of immunoglobulin G subclass 1, or IgG1 (a protein commonly found in the body), enabling Eloctate to use a naturally occurring pathway to extend the time the therapy remains in the body.

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The Pharma Data

JULY 6, 2021

Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that new data from its haemophilia A clinical programme will be presented at the virtual International Society on Thrombosis and Haemostasis (ISTH) 2021 Congress, from 17-21 July 2021. Roche’s Chief Medical Officer and Head of Global Product Development.

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Drug Target Review

NOVEMBER 29, 2023

This is a key differentiation factor that sets Alchemab apart and is the engine that drives our target discovery process. We focus on patients who are resilient to disease and conduct an unbiased search for protective autoantibodies in these patients that may underlie their resiliency.

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Engineering Drug Development Disease Research 112

Common Sense for Drug Policy Blog

OCTOBER 4, 2024

Consumer Protection and Vape Products "The 2021 review of cannabis policy found that states also have limits on ingredients that can be contained in cannabis products. Many states have banned or are testing for vitamin E acetate because of the 2019 outbreak of e-cigarette or vaping product–associated lung injury (EVALI) (Schauer, 2021).

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The Pharma Data

JANUARY 19, 2021

19, 2021 (GLOBE NEWSWIRE) — Fulcrum Therapeutics, Inc. The offering is expected to close on January 22, 2021, subject to customary closing conditions. Fulcrum’s proprietary product engine identifies drug targets which can modulate gene expression to treat the known root cause of gene mis-expression. CAMBRIDGE, Mass.,

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Small Molecule Clinical Development Treatment Disease 40

Broad Institute

JUNE 26, 2023

In fifth grade, Mangum joined a Girl Scout troop and the troop leaders, who had PhDs in science or engineering, further nurtured her interests by introducing her and her fellow troop members to many STEM activities — science camps for girls, LEGO robotics competitions, DNA extractions from strawberries.

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The Pharma Data

MARCH 9, 2021

Myles O’Neill, senior vice president and president of Lilly manufacturing operations, will retire May 2, 2021 after nearly 19 years of service with the company. Melissa Barnes, senior vice president and chief ethics and compliance officer, will retire June 27, 2021 after more than 26 years with the company. Source link:[link].

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The Pharma Data

JANUARY 24, 2021

25, 2021 /PRNewswire/ — Notch Therapeutics Inc., Dr. Bond joins Notch from Kite, where he most recently served as Vice President of Cellular Engineering. Bond joins Notch from Kite, where he most recently served as Vice President of Cellular Engineering. . VANCOUVER, BC , Jan.

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Science Engineering Therapies Pharmaceutical Companies 52

Drug Target Review

SEPTEMBER 22, 2023

Engineering organoids. 2021 Feb 19;6(5):402–20. CRISPR engineering in organoids for gene repair and disease modelling. Organoid vs In Vivo Mouse Model: Which is Better Research Tool to Understand the Biologic Mechanisms of Intestinal Epithelium? CMGH [Internet]. 2022;13(1):195–7. Available from: [link] Hofer M, Lutolf MP.

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Broad Institute

MARCH 18, 2024

Nature 598, 159–166 (2021). in neural engineering from Penn State University, and M.S. Before embarking on a life science career, Huo pursued her undergraduate study in software engineering at Tsinghua University, and mathematics and physics at the University of Hong Kong. Published 2023 Jun 30. doi:10.1371/journal.pbio.3002133

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The Pharma Data

JANUARY 31, 2021

1, 2021 00:00 UTC. SAN DIEGO–( BUSINESS WIRE )– January 31, 2021— Illumina, Inc. The company creation engine will focus on building life sciences startup companies advancing breakthrough applications in genomics. The inaugural funding cycle of the genomics incubator will begin in Fall 2021.

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Perficient: Drug Development

AUGUST 19, 2024

A CDO analyst on the market risk side, for instance, will have to be well versed with market data, bank hierarchies, VaR Calculation engines, Risk not in VaR (RNiV); supporting reference data in addition to the trade systems data that these data elements will have a direct or indirect impact on. Notwithstanding the critical data elements.

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Drug Target Review

FEBRUARY 28, 2024

These include engineering the cells to express cytokines that promote their maturation and/or differentiation, and engineering drug-resistant γδ T cells that can be combined with chemotherapies, which stress cancer cells but would otherwise also deplete the T-cell population. in Biochemistry from McMaster University.

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Therapies Engineering Molecular Biology Science 105

Broad Institute

SEPTEMBER 15, 2023

TBD By lcopelan@broadinstitute.org September 15, 2023 Alexander Lin School of Engineering and Applied Sciences, Harvard University MIA About Current Schedule Video Playlist Resources All talks Contact us MIA Talks Search - Any - Fall 2023 Spring 2023 Spring 2024 Fall 2022 Spring 2022 Fall 2021 Spring 2021 Fall 2020 Spring 2020 Fall 2019 Spring 2019 (..)

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Engineering Science 40

Broad Institute

AUGUST 31, 2023

Theoretical background regarding GANs and Causal GAN By lcopelan@broadinstitute.org August 31, 2023 Yazdan Zinati McGill University, Electrical and Computer Engineering, Montréal, Canada MIA About Current Schedule Video Playlist Resources All talks Contact us MIA Talks Search - Any - Spring 2023 Fall 2022 Spring 2022 Fall 2021 Spring 2021 Fall 2020 (..)

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Engineering 40

Common Sense for Drug Policy Blog

OCTOBER 4, 2024

In 2021, the NSDUH introduced the diagnostic category of cannabis use disorder to better accord with DSM-V criteria for classifying substance use disorders. dwf_admin Fri, 10/04/2024 - 11:53 Source National Academies of Sciences, Engineering, and Medicine. Cannabis Policy Impacts Public Health and Health Equity.

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Engineering Science 52

The Pharma Data

MARCH 4, 2021

Barbara Lavernos took over in February 2021 as President Research, Innovation and Technologies of the L’Oréal Group, having spent her entire career at l’Oréal, which she joined in 1991. Source link:[link].

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The Pharma Data

JANUARY 26, 2021

27, 2021 05:50 UTC. With a history of 22 years, WSG is the world’s leading manufacturer and supplier of meticulously precision-engineered flow components for ultra-high-purity (UHP) applications, servicing industries such as semiconductors, LCD/OLED displays, microelectronics, biotechnology, life sciences and pharmaceuticals.

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The Pharma Data

MARCH 13, 2021

Two representatives of the stockholders are to be put forward for election to the Bayer AG Supervisory Board at the company’s Annual Stockholders’ Meeting on April 27, 2021. Fei-Fei Li studied Physics, Computer Science and Engineering at Princeton University, where she gained a B.A. Li is a U.S. in Business Administration.

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International Engineering Science Marketing 52

The Pharma Data

APRIL 14, 2021

Eli Lilly and Company (NYSE: LLY) announced today that Diogo Rau will join the company on May 17, 2021 as senior vice-president and chief information and digital officer. Rau graduated from Stanford University with a bachelor’s degree in computer science and a master’s degree in industrial engineering and engineering management.

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Engineering Government Science 52

The Pharma Data

SEPTEMBER 1, 2021

Louis have genetically engineered cells that, when implanted in mice, will deliver a biologic drug in response to inflammation. The engineered cells reduced inflammation and prevented a type of damage to bone, known as bone erosion, in a mouse model of rheumatoid arthritis. Science Advances, Sept. 10.1126/sciadv.abj1414.

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The Pharma Data

JANUARY 6, 2021

6, 2021 /PRNewswire/ — A team from KAIST has developed a low-cost and ready-for-rapid-production negative pressure room called a Mobile Clinic Module (MCM). KAIST was established in 1971 by the Korean government to educate scientists and engineers committed to the industrialization and economic growth of Korea. About KAIST.

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Hospitals Engineering Nurses Science 52

Codon

JUNE 11, 2024

3 Nanopore engineers decided to cleverly exploit the natural speed limit of DNA polymerase to slow down DNA translocation through the pores. Trends in Genetics (2021). Stephen Malina is Head of Engineering at Dyno Therapeutics, a company using machine learning to design better viral vectors for gene therapy. Credit: Wan Y.K.

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DNA Engineering RNA Small Molecule 98

Drug Target Review

JUNE 12, 2023

Using the structure properties of existing TEADs – which proved to be ideal in terms of pocket size and shape cavity – the Chemistry42 engine created a novel scaffold that was used as the basis for a number of possible inhibitors.

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The Pharma Data

JANUARY 25, 2021

25, 2021 (GLOBE NEWSWIRE) — Ambulero, Inc. , Ambulero’s cell therapy program uses stromal cells engineered to express E-selectin to promote tissue repair. MIAMI, Jan. a biotechnology company developing cell and gene therapy treatments for patients suffering from vascular disease, today announced that it raised up to $5.5M

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The Strateos Blog: Drug Discovery

OCTOBER 8, 2021

Strateos was pleased to sponsor a webinar on Sept 27, 2021 to discuss how a single unified cloud-based software platform can overcome current operational inefficiencies in life science R&D labs.

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Science Engineering Production 52

Drug Target Review

JULY 5, 2024

The biosensor-OOC micro-engineered models can help elucidate the complexity of GBM by recapitulating brain tumour vasculature and replicating aspects of the tumour microenvironment, comprised of cell proliferation, migration and tangled cell interactions between tumour and endothelial cells. 13(2):280 (2021). Pharmaceutics.

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