Drug Target Review

MARCH 19, 2024

In the current study undertaken by an international team of researchers, co-led by Dr William Reay, we used the genetics of retinol itself as a way to proxy its effect in thousands of traits, including brain structure, vision, and the immune system through causal modelling.

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Drug Target Review

MARCH 28, 2024

1 Researchers have also observed a correlation between greater translatability of natural products and increased progression through clinical trials. This can allow researchers to routinely uncover about 10,000 distinct molecules per plant sample, each of which has the potential to interact with human biology and inspire new medicines.

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Nvidia Developer: Drug Discovery

DECEMBER 19, 2023

The applications of artificial intelligence for enzyme generation is an exciting field of research with direct applications in the life sciences. Improved methods for functional annotation are a vital component in enzyme research, enabling the identification and characterization of the functions of newly discovered enzymes.

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The Open Targets Blog

OCTOBER 24, 2023

Amir Feizi is the Director of Bioinformatics at OMass Therapeutics, a spinout from Professor Dame Carol Robinson’s Laboratory at the University of Oxford. Their work was recently published in Bioinformatics. We chat with him about otargen, and the importance of sharing open-source resources within the bioinformatics community.

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Practical Cheminformatics

JANUARY 8, 2024

Aside from some very brief demos on code generation and literature searches, mentions of LLM applications in preclinical research were scarce. A preprint from Microsoft AI Research provided a broad catalog of potential LLM applications in the physical and life sciences. Most of the drug discovery examples were underwhelming.

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Broad Institute

JULY 10, 2023

Thanks in part to her research, more geneticists are now studying a wider diversity of people and accounting for genetic ancestry in their analyses. Through this work, Martin is showing how a methodical, data-driven kind of social justice can help improve equity in scientific research and lead to better science.

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The Pharma Data

JANUARY 24, 2021

His research focuses on the role of the microbiome in immune defense and disease resistance. “We Diversigen provides consultative end-to-end solutions for sequencing, bioinformatics, and statistical analysis for the study of the microbiome of living organisms and environments. For more information, visit www.orasure.com.

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Broad Institute

AUGUST 29, 2016

Research Our unique structure, organized around core faculty labs, scientific programs, and scientific platforms, allows us to generate massive amounts of data and develop breakthrough technologies to analyze them. Where would you fit at the Broad? Click on a category below to learn more about the kinds of opportunities we have available.

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Broad Institute

SEPTEMBER 30, 2024

In this Q&A, we spoke to MacInnis and Park about the features that make Terra a useful tool in public health contexts as well as how it became indispensable during COVID-19 and continues to impact research today. What makes Terra so effective for the public health workforce?

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The Open Targets Blog

FEBRUARY 29, 2024

  With a background in biochemistry and bioinformatics, Lucy was interested in exploring how bioinformatics was applied to real-world healthcare data. I just graduated with a degree in Bioinformatics, and I was interested to see how the skills I learned could be applied.

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Drug Target Review

SEPTEMBER 26, 2024

Cresset delivers software solutions and contract research expertise enabling companies around the world to accelerate their small molecule discovery processes efficiently and effectively. AI can conduct the data analysis and candidate generation, leaving researchers to focus on more strategic and creative aspects of drug discovery.

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Broad Institute

AUGUST 20, 2024

Doing computational biology research as an undergraduate, as well as having supportive research advisors, inspired her to stay in research. Studying only biology limits you to a specific type of research, and the same goes for computer science. What is it like to juggle computational and wet lab research?

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The Pharma Data

MARCH 20, 2021

The Kluyver Center for Genomics of Industrial Fermentation in Delft, Holland, is a consortium of several different Universities and Research Centres. An in-situ CO2 sensor delivers information on the liquid phase of the bioreactor. The InPro 5000 sensor from METTLER TOLEDO enables precise and reliable. Scope of possible application .

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The ChEMBL-og

MARCH 13, 2023

The next UKQSAR meeting will be held at the European Bioinformatic Institute (EBI) on 20th April. EMBL-EBI, Wellcome Genome Campus, Hinxton, Cambridgeshire, CB10 1SD, UK Google map directions Please find information on traveling to EMBL-EBI on our website. This is where the ChEMBL team is also located!

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Bioinformatics Research Drugs 52

Vial

DECEMBER 5, 2023

Next-generation sequencing (NGS) has revolutionized scientific research and clinical genomics due to high-throughput multiplexing and shed light on genome structure, function, and dynamics. It has become a fundamental tool for researchers to explore the complexities of genetic information and conduct genetic-informed drug development.

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Drug Target Review

MAY 27, 2024

Caris Discovery, the therapeutic research arm of Caris Life Sciences, was launched to address the paucity of novel oncology drug targets and is uniquely poised to discover first-in-class ADC targets. Can you discuss any recent advancements or breakthroughs in ADC-related research or development that Caris has been involved in?

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Clinical Trials Science Molecular Biology Bioinformatics 59

The Pharma Data

MARCH 2, 2021

Boehringer Ingelheim and Gubra today announced a new research and licensing agreement focused on the identification and validation of targets and innovative peptide compounds for the treatment of obesity. Senior Vice President and Global Head of Cardiometabolic Diseases Research, Boehringer Ingelheim. About Gubra.

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DrugBank

FEBRUARY 12, 2025

The journey from bench to bedside often spans over a decade, consuming billions of dollars in research and development (R&D) expenditure, with a significant probability of failure at each phase. In Silico Drug Repurposing Advances in bioinformatics and systems biology have fueled the rise of repurposing of in silico drugs.

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The Pharma Data

OCTOBER 20, 2020

and RESEARCH TRIANGLE PARK, N.C. , We are confident in our future thanks to our fundamental attributes, namely our obsession with quality and innovation, the power of our brands, our entrepreneurial culture, and our bioinformatics leadership. SILVER SPRING, Md.

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The Pharma Data

NOVEMBER 23, 2020

and RESEARCH TRIANGLE PARK, N.C. , We are confident in our future thanks to our fundamental attributes, namely our obsession with quality and innovation, the power of our brands, our entrepreneurial culture, and our bioinformatics leadership. Report available at corporateresponsibility.unither.com. SILVER SPRING, Md.

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Broad Institute

AUGUST 4, 2022

Beyond genetic sequences, the expression patterns of certain genes further subcategorized CLL and provided valuable prognostic information. This work was supported by the National Institutes of Health and the Broad/IBM Cancer Resistance Research Project. The study was also led by José I. Martín-Subero (IDIBAPS), Xose S.

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The Pharma Data

SEPTEMBER 11, 2021

Senior Corporate Vice President and Global Head of Discovery Research at Boehringer Ingelheim. “We Twist and Boehringer Ingelheim will work together to validate and optimize any resulting new antibody candidates, which could be researched against a range of therapeutic areas. Wood, Ph.D., About Twist Bioscience Corporation.

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DNA Bioinformatics Production Engineering 52

Broad Institute

MARCH 11, 2024

How is the research wing of the STP organized? To guide the discussion, it is helpful to arrive at the meeting with the following information: What is the overall goal of the project? A comment on your comfort level with bioinformatics, images, and custom analysis. What question do you hope spatial can answer?

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The Pharma Data

DECEMBER 27, 2020

and RESEARCH TRIANGLE PARK, N.C. , IMPORTANT SAFETY INFORMATION FOR TYVASO. Limited case reports of treprostinil use in pregnant women are insufficient to inform a drug-associated risk of adverse developmental outcomes. For additional information about TYVASO, visit www.tyvaso.com or call 1-877-UNITHER (1-877-864-8437).

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DrugBank

MARCH 15, 2023

This helps us see the larger impact that their departments and organizations are making, which helps inform our work. Our relationship often starts with a tailored onboarding program intended to make incorporating DrugBank knowledge into their research or software faster and easier.

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The Open Targets Blog

APRIL 19, 2022

In particular, bibliography is a unique source of information to identify and prioritise targets since the whole corpus of literature represents the accumulated knowledge driving therapeutic discoveries. How can we systematically query that knowledge to provide researchers with the most relevant information?

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The Pharma Data

DECEMBER 16, 2020

Evotec receives undisclosed milestone payments as well as research funding for the further development of the programmes and can earn further significant success-based milestone payments. For additional information please go to www.evotec.com and follow us on Twitter @Evotec.

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The Pharma Data

JULY 27, 2021

Acquisition Complements Amgen’s Antibody Research Capabilities Across Therapeutic Areas Acquisition Includes a Portfolio of Early-Stage Oncology Assets, Including a Phase 1 Bispecific Antibody for Patients With Advanced Prostate Cancer. executive vice president of Research and Development at Amgen. Reese, M.D.,

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BMG Labtech

OCTOBER 4, 2023

2 DNA sequencing is also reliant on sample processing and DNA library preparation before sequencing as well as bioinformatics and data analysis after sequencing. Researchers will typically use commercially available kits for nucleic acid extraction compatible with their sample. How can you use microplate readers for NGS research?

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The Pharma Data

OCTOBER 27, 2020

and RESEARCH TRIANGLE PARK, N.C. , Research and development expense. The table below summarizes research and development expense by major category (dollars in millions): . Research and development projects. SILVER SPRING, Md. .

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Conversations in Drug Development Trends

APRIL 7, 2025

Solid tumors present a significant challenge to clinical research due to their complex and heterogeneous nature. Proactively Address Key Recruitment Challenges in Solid Tumor Clinical Research Solid tumor clinical research is challenging, especially because of tumor heterogeneity.

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DrugBaron

NOVEMBER 22, 2022

To enable that research, the team at Methuselah Health needed a proteomics approach that would accurately quantify post-translational modifications across the proteome – and since that didn’t exist, their Chief Technology Officer, David Mosedale, set about creating it.

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The Pharma Data

NOVEMBER 15, 2020

In this single target research collaboration Lead Pharma and Roche will collaborate in research activities up to the selection of a pre-clinical candidate after which Roche will be responsible for further development and global commercialization. For more information visit: www.leadpharma.com. . OSS, Netherlands , Nov.

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Broad Institute

APRIL 25, 2024

Partnering with researchers on the ground to reach communities where they are is absolutely critical to making that a reality.” “We The Sentinel team has also trained more than 1,600 scientists from all 54 African countries in genomics, diagnostics, and bioinformatics. We learned a lot from Ebola,” Happi said. “We

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The Premier Consulting Blog

JUNE 18, 2023

This has opened new opportunities in pharmaceutical drug development, such as the ability to evaluate large complex databases and to integrate information in useful ways. These data inform the construction of disease mechanistic models used to generate a synthetic control arm for use in the trial.

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Drug Target Review

SEPTEMBER 30, 2024

This functional research works. People see it as a challenge because most use computational work to inform their experimental work. Dr Ofran received a PhD with distinction in Molecular Biophysics and Biomedical Informatics from Columbia University and was a professor of bioinformatics and molecular research at Bar-Ilan University.

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The Pharma Data

OCTOBER 21, 2020

and RESEARCH TRIANGLE PARK, N.C. , ” The research, The Impact of Inhaled Treprostinil on Patient Lung Function: Results from the INCREASE Study, was presented by Aaron Waxman , M.D., IMPORTANT SAFETY INFORMATION FOR TYVASO. For Consumer Important Safety Information, please see [link]. SILVER SPRING, Md.

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