Drugs.com
JUNE 12, 2025
THURSDAY, June 12, 2025 — A newly approved shot could soon help protect babies from respiratory syncytial virus (RSV), the top cause of hospitalization in U.S. infants. The U.S. Food and Drug Administration (FDA) has approved a monoclonal.
BioPharma Drive: Drug Pricing
JUNE 12, 2025
Valued at $1.25 billion, the deal expands BioNTech’s cancer drug portfolio and heads off royalty costs it could have owed CureVac in ongoing patent litigation.
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Collaborative Drug
JUNE 12, 2025
Explore new AI+ and curve fitting tools in CDD Vault for structure prediction, docking, and assay analysis. Now available with no setup required.
Covalent Modifiers
JUNE 12, 2025
Tibor Viktor Szalai, Vincenzo di Lorenzo, Nikolett Péczka, Levente M. Mihalovits, László Petri, Qirat F. Ashraf, Elvin D. de Araujo, Viktor Honti, Dávid Bajusz, and György M. Keserű ACS Medicinal Chemistry Letters 2025 16 (6), 991-997 DOI: 10.1021/acsmedchemlett.4c00622 The STAT family of transcription factors are important signaling hubs, with several of them, particularly STAT3, being emerging oncotargets already investigated in clinical trials.
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
Science Daily: Pharmacology News
JUNE 12, 2025
A team of scientists has discovered a direct link between the smell of food and feelings of fullness at least in lean mice. This brain circuit, located in the medial septum and triggered by food odors, helps animals eat less by making them feel satiated even before taking a bite. But intriguingly, obese mice lacked this response, highlighting how excess weight may interfere with this satiety mechanism.
Drugs.com
JUNE 12, 2025
THURSDAY, June 12, 2025 — Some nasal and baby teething swabs from Zicam and Orajel are being recalled across the country because they may be contaminated with fungus, U.S. health officials said.The recall was announced by the U.S. Food and Drug A.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Drugs.com
JUNE 12, 2025
THURSDAY, June 12, 2025 — Days after ousting all 17 members of the panel that makes U.S. vaccine recommendations, Health Secretary Robert F. Kennedy Jr. has begun remaking it. On Wednesday, he named eight appointees, three of whom are critics.
Science Daily: Pharmacology News
JUNE 12, 2025
Reef "beauty salons" staffed by tiny cleaner fish aren t just for parasite removal they may also shape the microbial life of the entire ecosystem. A fascinating new study shows these bustling fish stations influence which microbes move around the reef, possibly helping or harming coral health. Cleaner gobies, it turns out, don t just offer spa treatments to their fish clients they may also serve as tiny microbiome engineers of the sea.
Drugs.com
JUNE 12, 2025
THURSDAY, June 12, 2025 — A hallmark of accelerated aging appears to be linked to an increased risk of dementia and stroke, a new study says.Shorter telomere length in a person’s white blood cells is associated with the two brain diseases, res.
Science Daily: Pharmacology News
JUNE 12, 2025
Despite Earth's most devastating mass extinction wiping out over 80% of marine life and half of land species, a group of early reptiles called archosauromorphs not only survived but thrived, venturing across the supposedly lifeless tropics to eventually evolve into the dinosaurs and crocodiles we know today. Armed with a groundbreaking model dubbed TARDIS, researchers have reconstructed their ancient dispersal routes, revealing how these resilient reptiles conquered a hostile, post-apocalyptic E
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Drugs.com
JUNE 12, 2025
THURSDAY, June 12, 2025 — Most folks tap away at their smartphone for fun, communication or information.But such tapping may also help them track the progress of a rare degenerative brain disease, researchers say.Five simple smartphone-measured t.
Nvidia Developer: Drug Discovery
JUNE 12, 2025
Protein sequence alignment—comparing protein sequences for similarities—is fundamental to modern biology and medicine. It illuminates gene functions by. Protein sequence alignment—comparing protein sequences for similarities—is fundamental to modern biology and medicine. It illuminates gene functions by reconstructing evolutionary relationships, technically called homology inference, that can inform drug development.
Drugs.com
JUNE 12, 2025
THURSDAY, June 12, 2025 — A person’s smartwatch can capture a lot of data about their health – and a new study says most folks are willing to share it with doctors.About 94% of people who wear smartwatches or activity trackers are open to sharing da.
Science Daily: Pharmacology News
JUNE 12, 2025
Data from NASA's James Webb Space Telescope has revealed dozens of small galaxies that played a starring role in a cosmic makeover that transformed the early universe into the one we know today.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
BioPharma Drive: Drug Pricing
JUNE 12, 2025
Days after firing all 17 members of the CDC's Advisory Committee for Immunization Practices, the HHS Secretary named a small new committee that includes multiple vaccine critics.
Chemical Biology and Drug Design
JUNE 12, 2025
Schematic of the mechanism of LYC in treating osteoporosis through the ESR1/PI3K/AKT pathway. LYC upregulates ESR1 expression and thus leads to the activation of the PI3K/AKT pathway, thereby inducing hBMSC osteogenic differentiation and attenuating osteoporosis development. ABSTRACT Osteoporosis is a widespread metabolic bone disorder. Lycopene (LYC), a potent antioxidant in tomatoes, has been shown to exhibit anti-osteoporosis effects.
Drugs.com
JUNE 12, 2025
THURSDAY, June 12, 2025 — A “vicious circle” might exist between screen time and troubled children, a new evidence review says.Screen time — particularly on video games — appears to contribute to emotional turmoil among children, researchers say.Tho.
LifeSciVC
JUNE 12, 2025
By Ram Aiyar, CEO of Korro Bio, as part of the From The Trenches feature of LifeSciVC It has been an extraordinary journey so far and one that continues to humble, inspire and motivate me every day. I’ve had the honor and responsibility of building a visi on that is ambitious while being grounded in scientific rigor. Over the last 4.5 years, Korro has been built by mitigating one layer of risk at a time.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Codon
JUNE 12, 2025
The UK’s Advanced Research and Invention Agency (ARIA) is often referred to as a “UK DARPA” While ARIA is no DARPA clone, many features of the agency are admittedly DARPA-inspired, such as the use of term-limited program managers, which ARIA calls program directors. These program directors serve as chief visionaries for their programs as well as fund and actively manage teams of coordinated external researchers towards a program's well-defined goal.
Elrig
JUNE 12, 2025
Drug Discovery 101 – Webinar Recording Starting a career in drug discovery can feel overwhelming, but breaking down the process makes it more approachable. Our Drug Discovery 101 webinar outlines the entire process from start to finish. Here’s what you need to know to begin your journey in the field. The Basics of Drug Discovery Finding the Right Target The first step in drug discovery is all about identifying and confirming a target—something in the body that a drug can influence to impro
Drugs.com
JUNE 12, 2025
THURSDAY, June 12, 2025 — Bisexual, gay and lesbian medical students are more likely to leave school before graduation, a new study says.Bisexual medical students were twice as likely to drop out or be dismissed from medical school, and gay and l.
Nvidia Developer: Drug Discovery
JUNE 12, 2025
The future of cell biology and virtual cell models is dependent on measuring and analyzing data at scale. Single-cell experiments have been growing at an. The future of cell biology and virtual cell models is dependent on measuring and analyzing data at scale. Single-cell experiments have been growing at an incredible rate over the last 10 years, beginning with hundreds of cells and now moving towards new data generation efforts with billions of cells.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Fierce BioTech
JUNE 12, 2025
The Importance of Proper CDMO Selection for Rare Disease Drug Programs swheeler Thu, 06/12/2025 - 15:18 Thu, 07/17/2025 - 13:00 Resource Type Webinar Chris Olson Promotion Start Wed, 06/18/2025 - 09:00 Promotion End Thu, 12/18/2025 - 09:00 Factors to consider when selecting a CDMO for a rare disease drug: Available capacity and flexibility Financial stability Expertise in formulation development Strong technical experience with difficult to manufacture products Expertise in global regulatory com
Broad Institute
JUNE 12, 2025
Tal Shnitzer By Rose Circeo June 12, 2025 Tal Shnitzer, Ph.D. Senior Machine Learning Scientist Tal Shnitzer is a senior machine learning scientist in the ML4H team at the Broad Institute. She develops machine learning algorithms for disease risk prediction and classification using various biomedical modalities, ranging from clinical measurements such as echocardiograms to wearable sensor data such as Fitbit recordings.
The Pharma Data
JUNE 12, 2025
Bleximenib Shows Promise in AML When Combined with Venetoclax and Azacitidine, According to Johnson & Johnson’s Phase 1b Data Presented at EHA 2025 Johnson & Johnson today presented new and promising Phase 1b data demonstrating strong antileukemic activity and a favorable safety profile for bleximenib (JNJ-75276617) in combination with venetoclax (VEN) and azacitidine (AZA) in patients with acute myeloid leukemia (AML) who harbor KMT2A gene rearrangements (KMT2Ar) or NPM1 mutations (NPM1
Broad Institute
JUNE 12, 2025
Danielle Pace By Rose Circeo June 12, 2025 Danielle Pace Senior Machine Learning Scientist Danielle Pace is a senior machine learning scientist in the Machine Learning for Health team at the Broad Institute of MIT and Harvard. She develops machine learning models that use large clinical datasets, including medical images, electronic health records, ECGs, and genetics, to better understand disease, learn useful data representations, and predict disease risk.
The Pharma Data
JUNE 12, 2025
EULAR 2025: Rilzabrutinib Shows Promise in IgG4-Related Disease — Reduction in Flares and Disease Activity Rilzabrutinib , a Bruton’s tyrosine kinase (BTK) inhibitor currently in clinical development, demonstrated a significant and sustained reduction in disease flares and key disease activity markers in patients with IgG4-related disease (IgG4-RD) , according to new data presented at the European Alliance of Associations for Rheumatology (EULAR) 2025 Congress in Barcelona, Spain (June 11–14).
Drug Patent Watch
JUNE 12, 2025
"Revolutionizing the Industry: How Innovations in Generic Drug Manufacturing Are Transforming Products and Reducing Costs As the pharmaceutical industry continues to evolve, one thing is clear: the future of generic drugs is not just about cheaper alternatives, but about better, more effective treatments. At the forefront of this revolution are innovations in generic drug manufacturing and formulation, which are transforming products and reducing costs.
The Pharma Data
JUNE 12, 2025
Bristol Myers Squibb Highlights Targeted Protein Degradation Advances, Including CELMoD Agents and BCL6 Ligand-Directed Degrader, at EHA 2025 in Milan, Italy Bristol Myers Squibb today revealed new and updated data from its growing portfolio of targeted protein degradation programs during the 2025 European Hematology Association (EHA) Annual Congress, which is currently underway from June 12-15 in Milan, Italy.
PLOS: DNA Science
JUNE 12, 2025
About 100 million adults and 100 million children worldwide have the red, flaky, itchy skin of the most common form of eczema, atopic dermatitis, according to the NIH. The condition stems from a misdirected immune response to a substance – an allergen – that does not actually present a threat. Although the exact causes of eczema aren’t well understood, a new study points to an unexpected protective factor: owning a dog.
The Pharma Data
JUNE 12, 2025
Novartis’ Fabhalta Shows Meaningful Hemoglobin Improvement in PNH Patients, Reinforcing Benefit of Oral Monotherapy Novartis recently announced positive results from its APPULSE-PNH study — a Phase IIIB trial evaluating Fabhalta® (iptacopan) in adult patients with paroxysomal nocturnal hemoglobinuria (PNH) who have a baseline hemoglobin (Hb) level of 10 g/dL or greater and have previously been treated with standard C5 inhibitor therapy (eculizumab or ravulizumab).
Quanticate
JUNE 12, 2025
Utilising the newer SAS graphical procedures such as SGPLOT and SGPANEL rather than the original SAS Graph procedures is becoming more and more popular in statistical programming through their many user friendly utilities, such as overlaying multiple graphics and adding reference lines with ease. However, as with its predecessor, SAS Graph, any requirement for restructure of the graphical elements still proves to be relatively rigid when sticking to these core graphical procedures.
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