Science Daily: Pharmacology News
SEPTEMBER 16, 2024
An experiment tested six generative large language models against students in an online introductory biomedical and health informatics course. The models scored higher than as many as three quarters of the real-world students in the class.
Drugs.com
SEPTEMBER 16, 2024
MONDAY, Sept. 16, 2024 -- Tiny puffs from asthma inhalers could be causing big climate problems for Mother Earth, a new study warns.Each inhaler dose contains some of the most potent greenhouse gases known, and they are adding up, researchers.
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Science Daily: Pharmacology News
SEPTEMBER 16, 2024
Researchers follow the dramatic changes that occur in the brain throughout the course of pregnancy.
Drugs.com
SEPTEMBER 16, 2024
MONDAY, Sept. 16, 2024 -- Fatty liver disease linked to diabetes and obesity can easily progress to liver cirrhosis, but new research suggests that GLP-1 medicines like Ozempic can help stop that. In a new decades-long study, veterans with diabetes.
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
Science Daily: Pharmacology News
SEPTEMBER 16, 2024
New research examines thousands of years of Arctic sled dog ancestry and reveals when and how Siberian and Alaskan sled dogs' DNA mixed.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
BioPharma Drive: Drug Pricing
SEPTEMBER 16, 2024
Legislation that passed the House of Representatives passed the Biosecure Act last week would forced U.S. biotechs to cut ties with five Chinese contract partners.
Drugs.com
SEPTEMBER 16, 2024
MONDAY, Sept. 16, 2024 -- Vaping may look cool when you're young, but it appears to be dulling the brains of college students, a new study warns.College students who vape have lower cognitive function scores than those who don't, researchers.
BioPharma Drive: Drug Pricing
SEPTEMBER 16, 2024
Applying a systems thinking approach can create improvements in scientific integrity, operational feasibility and scalability.
Drugs.com
SEPTEMBER 16, 2024
MONDAY, Sept. 16, 2024 (Healthday News) -- In a disclosure that can't eliminate the possibility that bird flu may have spread from one human to another for the first time, U.S. health officials have reported that a person who lived with a Missouri.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
BioPharma Drive: Drug Pricing
SEPTEMBER 16, 2024
Results for Pfizer’s ponsegromab looked promising, while BioNTech and Instil Bio capitalized on momentum surrounding a kind of bispecific antibody.
Drugs.com
SEPTEMBER 16, 2024
MONDAY, Sept. 16, 2024 -- People with rare genetic variants linked to degenerative brain disorders like Parkinson’s disease are at increased risk of developing ALS, a new study finds.Further, having these genetic variants increases the risk of a p.
BioPharma Drive: Drug Pricing
SEPTEMBER 16, 2024
There’s no doubt that AI and GenAI can speed up pharmaceutical innovation. But before organizations can jump into the future, it’s crucial to understand the benefits – and the risks – of advanced technology.
Drugs.com
SEPTEMBER 16, 2024
MONDAY, Sept. 16, 2024 -- Newfangled designs intended to make football helmets more protective have overlooked one key component, a new study suggests.Nearly a third of concussions in pro football involve impacts to the facemask, a part of the.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
ASPET
SEPTEMBER 16, 2024
Post-traumatic stress disorder (PTSD) is a debilitating psychiatric condition that develops following exposure to a traumatic event. Individuals with this condition experience numerous physiological and behavioral alterations, including intrusive memories, avoidance of trauma-related stimuli, heightened anxiety, hypervigilance, impaired cognition, elevated resting heart rate and blood pressure, and altered neuroendocrine function, to name a few.
BioPharma Drive: Drug Pricing
SEPTEMBER 16, 2024
Warner Biddle and Christi Shaw, two prominent former executives at Gilead’s CAR-T division, will try to turn around an autoimmune cell therapy developer that’s lost most of its value since raising $319 million in a February IPO.
Drugs.com
SEPTEMBER 16, 2024
MONDAY, Sept. 16, 2024 -- With implications for research around postpartum depression and other health issues, scientists have tracked the changes pregnancy brings to the female brain. These changes weren't subtle: Big shifts in what's known as the.
BioPharma Drive: Drug Pricing
SEPTEMBER 16, 2024
With a new production line, Sanofi aims to keep it and partner AstraZeneca’s drug Beyfortus in fully supply this RSV season.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Drugs.com
SEPTEMBER 16, 2024
MONDAY, Sept. 16, 2024 -- Many parents worry that their kids aren’t popular enough, or that they aren’t making the right friends, a new survey finds.About 1 in 5 parents say their child aged 6 to 12 has no friends or not enough friends, according to.
BioPharma Drive: Drug Pricing
SEPTEMBER 16, 2024
NGS is changing the landscape for GxP compliance. How can you adapt?
Antidote
SEPTEMBER 16, 2024
Receiving a Parkinson’s diagnosis is a life-altering event that nearly 1 million people in the United States have experienced. Parkinson’s disease symptoms can vary from person to person. Receiving a diagnosis often requires several steps. In this blog, we’ll be sharing more details about the disease and discussing opportunities for individuals to get involved in Parkinson’s research.
BioPharma Drive: Drug Pricing
SEPTEMBER 16, 2024
Applying CAR T-cell therapy in new clinical settings presents unique challenges. Worldwide Clinical Trials is at the forefront, partnering with drug development teams to map this new path forward.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Chemical Biology and Drug Design
SEPTEMBER 16, 2024
This study identified MAPK9 as the directly binding target of baicalein by the DNA-programmed affinity labeling method and tested the binding affinity as 89.7 nM by surface plasmon resonance. Baicalein stabilized MAPK9 to induce apoptosis in hepatocarcinoma cells, which would be helpful to understand and use baicalein in hepatocarcinoma therapy. ABSTRACT Hepatocellular carcinoma (HCC) is a significant global health concern.
ASPET
SEPTEMBER 16, 2024
Clinical reports suggest that the most effective strategies for managing opioid use disorder comprise a comprehensive treatment program of both pharmacological and non-pharmacological approaches. However, the conditions under which these combinations are most effective are not well characterized. This study examined whether the presence of an alternative reinforcer could alter the efficacy of FDA-approved opioid antagonist or agonist medications, as well as the non-opioid flumazenil, in decreasi
PPD
SEPTEMBER 16, 2024
The pharmaceutical industry is currently experiencing a significant transformation. The convergence of real-world data (RWD), technology and artificial intelligence (AI) is playing a vital role in accelerating drug development. In a recent panel discussion at DIA Global , our experts explored how these elements are reshaping clinical research and drug discovery.
ASPET
SEPTEMBER 16, 2024
Glioblastoma (GBM) is a disease of the whole brain, with infiltrative tumor cells protected by an intact BBB. GBM has a poor prognosis despite aggressive treatment, in part due to lack of adequate drug permeability at the BBB. Standard of care GBM therapies include radiation and cytotoxic chemotherapy that lead to DNA damage. Subsequent activation of DNA damage response (DDR) pathways can induce resistance.
NIOSH Science Blog: Drugs
SEPTEMBER 16, 2024
As part of Fungal Disease Awareness Week, we are highlighting fungal diseases that can affect workers. Coccidioidomycosis (Valley fever), blastomycosis, and histoplasmosis are fungal diseases caused by fungi that live in the environment in certain regions. Infections are caused by breathing in fungal spores that get into the air. Some jobs and work activities that disturb soil in areas where the fungi live can release fungal spores into the air and put workers at higher risk.
ASPET
SEPTEMBER 16, 2024
We previously identified a small molecule, UM101, predicted to bind to the substrate-binding groove of p38aMitogen-activated Protein Kinase (MAPK) near the binding site of its proinflammatory substrate, MAPK-activated protein kinase (MK2). UM101 exhibited anti-inflammatory, endothelial-stabilizing, and lung-protective effects. To overcome its limited aqueous solubility and p38a binding affinity, we designed an analog of UM101, GEn-1124, with improved aqueous solubility, stability, and p38a bindi
thought leadership
SEPTEMBER 16, 2024
As the pharmaceutical landscape in the Japan and Asia-Pacific (JAPAC) region continues to evolve, the demand for efficient, high-quality medical information (MI) services has never been greater. Our offshore contact centers in India and the Philippines offer pharmaceutical companies an unparalleled blend of innovation, customer excellence, and cost efficiency.
ASPET
SEPTEMBER 16, 2024
Mitochondrial dysfunction is a hallmark of many genetic neurodegenerative diseases, but therapeutic options to reverse mitochondrial dysfunction are limited. While recent studies support the possibility of improving mitochondrial fusion/fission dynamics and motility to correct mitochondrial dysfunction and resulting neurodegeneration in Charcot-Marie-Tooth disease (CMT) and other neuropathies, the clinical utility of reported compounds and relevance of pre-clinical models are uncertain.
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