Mon.Feb 24, 2025

article thumbnail

Pfizer names Patrizia Cavazzoni, former top FDA official, as chief medical officer

BioPharma Drive: Drug Pricing

Cavazzoni stepped down from her role as head of the FDA’s main drug review office in mid-January. She will succeed Aida Habtezion.

FDA 363
article thumbnail

Bottling a mouse 'superpower' may heal lungs damaged by premature birth

Science Daily: Pharmacology News

Using a four-dimensional microscopy technique, researchers have created 3D video images of mouse lung tissue grown in the laboratory. What they have learned has been nothing short of groundbreaking.

Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

article thumbnail

Ozempic, Wegovy Linked To Potential Vision Loss

Drugs.com

MONDAY, Feb. 24, 2025 -- People taking the weight-loss drug semaglutide could be at a slightly increased risk for a potentially blinding eye condition that affects the optic nerve, a new study says.Patients on semaglutide (Ozempic, Wegovy) had a.

Drugs 289
article thumbnail

Arctic study urges stronger climate action to prevent catastrophic warming

Science Daily: Pharmacology News

Remember when 2 degrees Celsius of global warming was the doomsday scenario? Well, we're now staring down the barrel of something much worse. From the fish on your plate to the weather outside your window, everything's about to change. A new study underscores the grave risks posed by insufficient national commitments to reducing greenhouse gas emissions.

299
299
article thumbnail

Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

article thumbnail

FDA brings back some fired device office staff

BioPharma Drive: Drug Pricing

An industry source said “most, if not all” of the people at CDRH who were recently dismissed are now being asked to return.

FDA 263

More Trending

article thumbnail

Texas Measles Outbreak Spreads to New Mexico as Case Numbers Near 100

Drugs.com

MONDAY, Feb. 24, 2025 -- Lea County, New Mexico, is now reporting an outbreak of measles, according to the New Mexico Department of Health (NMDOH). Lea County is near Gaines County, Texas, where measles cases continue to rise as part of the.

262
262
article thumbnail

Partnering for success in early phase clinical development

BioPharma Drive: Drug Pricing

Early-phase clinical trials, including phase 1 and some phase 2a studies, serve as a pivotal step for biotech companies, laying the foundation for a drug candidate’s journey to market.

article thumbnail

Bird Flu Found in Rats for First Time, USDA Confirms

Drugs.com

MONDAY, Feb. 24, 2025 -- For the first time, bird flu has been detected in rats, the U.S. Department of Agriculture (USDA) confirmed, according to a recent report.Bird flu, otherwise known as H5N1 avian influenza, was found in four black rats in.

246
246
article thumbnail

Research provides new detail on the impact of volcanic activity on early marine life

Science Daily: Pharmacology News

New analysis of ancient fossilized rocks known as stromatolites, preserved in southern Zimbabwe, suggests strong links to hydrothermal nutrient recycling, 'meaning that early life may in part have been fueled by volcanic activity'.

Research 207
article thumbnail

From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

article thumbnail

Lost Your Vaccine Records? Here’s How to Track Them Down

Drugs.com

MONDAY, Feb. 24, 2025 -- With measles cases on the rise and flu season straining the nation's hospitals, health experts urge adults to check their vaccination status and get any missing shots.Health experts agree that vaccines are the best defense.

Vaccine 232
article thumbnail

Summit partners with Pfizer to study bispecific, ADC combinations

BioPharma Drive: Drug Pricing

The partners will test Summit’s ivonescimab alongside Pfizer’s antibody-drug conjugates in hopes of finding “potentially landscape-changing combinations.

Drugs 194
article thumbnail

Narcissists Feel Left Out and Fuel More Rejection, Study Finds

Drugs.com

MONDAY, Feb. 24, 2025 -- Narcissists may seem self-assured, but new research shows they often feel excluded -- and their behavior may be making things worse.Hallmarks of narcissm include an inflated sense of one's importance, a hunger for.

Research 229
article thumbnail

Sanofi, Teva add to case for new bowel disease drug

BioPharma Drive: Drug Pricing

Detailed results presented at a medical congress help reinforce analyst expectations the drug, called duvakitug, will be competitive with other Crohn’s, colitis medicines in testing.

Disease 144
article thumbnail

How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

article thumbnail

Newborns With Seizures At Greater Risk of Epilepsy

Drugs.com

MONDAY, Feb. 24, 2025 -- A babys seizure in a neonatal ICU could be a red flag for future risk of epilepsy.Newborns who suffer seizures following birth are more likely to develop epilepsy in childhood and young adulthood, a new study suggests.More.

208
208
article thumbnail

Mirum drug for rare genetic disease gains FDA approval

BioPharma Drive: Drug Pricing

Mirum gained the drug, which it will sell as Ctexli for adults with cerebrotendinous xanthomatosis, in a 2023 deal with Travere Therapeutics.

article thumbnail

Weight-Loss Drugs Could Help Extend Life of Replacement Joints

Drugs.com

MONDAY, Feb. 24, 2025 (HealthDay news) -- Even slight weight loss spurred on by cutting-edge GLP-1 drugs can help prevent replacement knees and hips from wearing out, a new study suggests.People with new knees and hips are significantly less likely.

Drugs 179
article thumbnail

FDA Updates: What Do the Latest Changes Mean for Generic Drug Approval?

Drug Patent Watch

Breaking News: FDA Updates - What Do the Latest Changes Mean for Generic Drug Approval? Hey there, fellow healthcare professionals and industry experts! I'm excited to share with you the latest updates from the FDA that could significantly impact the generic drug approval process. As you may know, the FDA has been working tirelessly to improve the efficiency and transparency of the generic drug approval process.

FDA 52
article thumbnail

Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

article thumbnail

Parents' Mental Health Impacts Kids' Risk of ADHD, Anxiety

Drugs.com

MONDAY, Feb. 24, 2025 -- A parents mental health appears to influence their kids chances of developing anxiety, ADHD and other behavioral disorders, a new study says.Children were more than four times as likely to develop severe ADHD (at.

147
147
article thumbnail

Transforming Early Detection in Oncology and Rare Diseases Using AI

Fierce BioTech

Transforming Early Detection in Oncology and Rare Diseases Using AI pesurya Mon, 02/24/2025 - 09:53 Wed, 04/09/2025 - 11:00 Resource Type Webinar Chris Tackaberry Dr. Will Ricketts Health systems around the globe face a difficult paradox: delivering more care with fewer resources. This challenge is critical across various medical fields including oncology and rare diseases where advances in early detection can increase life expectancy and decrease the cost of care.

Disease 52
article thumbnail

Hospice, Palliative Care Underused Among Advanced Cancer Patients

Drugs.com

MONDAY, Feb. 24, 2025 -- Many patients with incurable cancer arent getting care that could ease their suffering at the end of life, a new study suggests.Close to half of patients with advanced cancer received aggressive cancer treatment within six.

Treatment 147
article thumbnail

Broad-MIT Seminars in Chemical Biology: Phil Holliger

Broad Institute

Broad-MIT Seminars in Chemical Biology: Phil Holliger By Rose Circeo February 24, 2025 Breadcrumb Home Broad-MIT Seminars in Chemical Biology: Phil Holliger Broad-MIT Seminars in Chemical Biology February 24, 2025 Broad Institute of MIT and Harvard Speaker: Phil Holliger, MRC Laboratory of Molecular Biology Talk title: Replicating RNA with RNA Description: A critical event in the origin of life is thought to have been the emergence of an RNA molecule capable of self-replication as well as mutati

RNA 52
article thumbnail

Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

article thumbnail

Exercise Helps Colon Cancer Survivors Live Longer

Drugs.com

MONDAY, Feb. 24, 2025 -- Frequent exercise can help colon cancer survivors live longer, perhaps even outlasting average folks, a new study suggests.Colon cancer patients who were very physically active had three-year survival rates that were.

147
147
article thumbnail

How EDC Software Minimizes Bias in Clinical Trials

Crucial Data Solutions

The Impact of Bias on Clinical Trials and Patient Safety Bias, despite best efforts and best intentions, continues to impact. The post How EDC Software Minimizes Bias in Clinical Trials appeared first on Crucial Data Solutions.

article thumbnail

Origin and diversity of Hun Empire populations

Science Daily: Pharmacology News

A multidisciplinary and international research project has brought fresh insights into the origins and diversity of the populations that lived under and after the Hun empire between the late 4th and 6th century CE in Central Europe. Combining forefront archaeogenomic analyses with archaeological and historical investigation, the study connects some of the European Hun-period individuals directly to some high-status elite of the earlier Xiongnu Empire -- a powerful nomadic empire centered in the

article thumbnail

Multiomics Analyses Demonstrate the Attenuation of Metabolic Cardiac Disorders Associated With Type 2 Diabetes by Stachydrine in Relation With the Transition of Gastrointestinal Microbiota

Chemical Biology and Drug Design

Administration of STA inhibits intestine tissue destruction and inflammation in T2D mice and improves intestinal permeability in T2D mice, which is associated with the transition of GI microbiota to a novel homeostasis. ABSTRACT Stachydrine (STA) has therapeutic effects on heart disorders. The current study assessed its effects on Type 2 diabetes (T2D) induced cardiac disorders by focusing on the heartgut axis.

Research 100
article thumbnail

February Fellow's Spotlight on Dr. Oleta Johnson

keypoint

Our February Fellow's Spotlight goes to Dr. Oleta Johnson! Dr. Johnsons is a William R. and Daniel L. Young Career Development Assistant Professor at MIT, where she uses chemical and biophysical tools to dissect the relationship between protein dynamics and function. Specifically, the Johnson Lab uses chemistry and biophysics to understand and tune molecular chaperone protein DnaJB6 and its ability to suppress the toxic accumulation of proteins associated with neurodegenerative diseases like Hun

Doctors 71
article thumbnail

Tell your Project’s Story using Azure DevOps Queries and Dashboards

Perficient: Drug Development

Sometimes purely looking at an Azure DevOps backlog or Board may not tell the right story in terms of progress made towards a specific goal. At first glance, it may seem like a horror story, but in reality, it is not the case. The data needs to be read in the right way. Though Azure DevOps provides multiple ways to view work items, it also provides a powerful reporting capability in terms of writing queries and configuring dashboards.

59
article thumbnail

Large language models: now more affordable and reliable than ever

Drug Target Review

While presenting at the recent SLAS conference in San Diego, 1 I found myself at the centre of numerous discussions about the seismic shifts occurring in the AI landscape ie, Deepseek R1 2,3 had just gone viral. As someone deeply involved in explaining large language models to life scientists both in wet labs and drug discovery I’ve developed a unique perspective on how recent developments are reshaping our industry.

Science 59
article thumbnail

How to Access Oracle Fusion Cloud Apps Data from Databricks

Perficient: Drug Development

Connecting to Oracle Fusion Cloud Applications data from external non-Oracle systems, like Databricks, is not feasible for bulk data operations via a direct connection. However, there are several approaches to making Oracle apps data available for consumption from Databricks. What makes this task less straightforward is the fact that Oracle Fusion Cloud Applications and Databricks exist in separate clouds.

59