Drug Discovery World

MAY 14, 2024

Semaglutide (the active ingredient in Wegovy and Ozempic) can produce clinically meaningful weight loss and delivers significant cardiovascular benefits, according to two studies presented at the European Congress on Obesity (ECO). The studies are based on the Semaglutide and Cardiovascular Outcomes (SELECT) trial, the largest and longest clinical trial of the effects of semaglutide on weight in over 17,000 adults.

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Science Daily: Pharmacology News

MAY 14, 2024

Cinematography techniques can significantly increase user engagement with virtual environments and, in particular, the aesthetic appeal of what users see in virtual reality.

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Drug Discovery World

MAY 14, 2024

DDW’s Megan Thomas talks to Dr Henrik Jespersen, Head of Melanoma Oncology, at Oslo University Hospital. MT: Where do you work, and can you tell us what you’re working on at the moment? HJ: I work as a clinical oncologist at Oslo University Hospital where I am head of melanoma oncology. I have a particular interest in tumour immunology and the melanoma subtype that arises in parts of the eye called uveal melanoma.

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Science Daily: Pharmacology News

MAY 14, 2024

The vast majority of people have an ongoing conversation with themselves, an inner voice, that plays an important role in their daily lives. But between 5-10 per cent of the population do not have the same experience of an inner voice, and they find it more difficult to perform certain verbal memory tasks, new research shows.

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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

Clinical Trials

Drug Discovery World

MAY 14, 2024

In the In Conversation With series, a part of the free DDW podcast, DDW speaks with members of the drug discovery industry about their work and how it helps turn science into business. In this episode, Megan Thomas is in conversation with Tien Lee, CEO of Aardvark Therapeutics, a San Diego-based biotech company in Phase II studies of its drug, ARD-101, a type 2 bitter taste receptor (TAS2R) which is taken orally and remains in the human gut unlike GLP-1 which is systemic.

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Science Daily: Pharmacology News

MAY 14, 2024

Researchers have found that 2023 was the hottest summer in the Northern Hemisphere in the past two thousand years, almost four degrees warmer than the coldest summer during the same period.

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Research 117

Science Daily: Pharmacology News

MAY 14, 2024

Artificial intelligence (AI) computer programs that process MRI results show differences in how the brains of men and women are organized at a cellular level, a new study shows. These variations were spotted in white matter, tissue primarily located in the human brain's innermost layer, which fosters communication between regions.

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Drug Discovery World

MAY 14, 2024

Safety and health concerns, time investment, and lack of support are the top three barriers to participation in clinical studies among ethnic minorities, according to a new report. The study examined the motivators and deterrents of clinical trial participation among ethnic minorities and outlined strategies sponsors can utilise to minimise deterrents and promote diversity in their research. “Diversity in clinical trials isn’t a nice to have, it’s a medical necessity.

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Perficient: Drug Development

MAY 14, 2024

In the ever-evolving landscape of healthcare, trust reigns supreme. As consumers increasingly rely on data to inform their decisions, the healthcare industry faces a pressing need to not only meet but exceed expectations. With disruptive forces emerging from various corners, healthcare organizations find themselves in a race to create personalized experiences that foster lasting engagement and trust.

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Drug Discovery World

MAY 14, 2024

In the In Conversation With series, a part of the free DDW podcast, DDW speaks with members of the drug discovery industry about their work and how it helps turn science into business. In this episode, Megan Thomas is in conversation with Tien Lee, CEO of Aardvark Therapeutics, a San Diego-based biotech company in Phase II studies of its drug, ARD-101, a type 2 bitter taste receptor (TAS2R) which is taken orally and remains in the human gut unlike GLP-1 which is systemic.

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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

Clinical Trials

Science Daily: Pharmacology News

MAY 14, 2024

Astronomers discovered three of the oldest stars in the universe, and they live in our own galactic neighborhood. The stars are in the Milky Way's 'halo' -- the cloud of stars that envelopes the entire main galactic disk -- and they appear to have formed between 12 and 13 billion years ago, when the very first galaxies were taking shape.

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Research 107

Drugs.com

MAY 14, 2024

TUESDAY, May 14, 2024 -- Semaglutide -- the active ingredient in the blockbuster weight-loss drugs Ozempic and Wegovy -- can produce long-term weight and heart health benefits, a pair of new studies show.Researchers found that overweight and obese.

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Science Daily: Pharmacology News

MAY 14, 2024

Survey reveals nearly three-quarters of U.S. adults support using emerging technology to screen embryos during IVF for risk of developing certain health conditions or traits that arise from more than one gene. Only about one-third of respondents approved of using the technology to predict traits unrelated to disease. Nearly all expressed concerns about potential negative outcomes for individuals or society.

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Perficient: Drug Development

MAY 14, 2024

We’re excited to announce our Data Cloud Expert specialization! This is the highest level of Salesforce-validated expertise for Data Cloud. This achievement isn’t just a milestone, it’s a testament to our commitment to revolutionizing how businesses leverage their data to drive business outcomes, unlock trapped data, and enhance customer experiences.

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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

Clinical Trials

Drugs.com

MAY 14, 2024

TUESDAY, May 14, 2024 -- High temperatures across the Northern Hemisphere last summer were scorching and frequent enough to make it the hottest summer in two millennia, new research shows.Weather records based on scientific instruments only goes.

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Drug Channels

MAY 14, 2024

Contrary to what you may have heard, the Inflation Reduction Act’s (IRA) inflation rebates for Medicare Part B drugs do not always save money for seniors. As we document below, a growing share of Part B drugs have inflation-adjusted coinsurance rates that have been increasing , not declining. In many cases, the coinsurance rate declines only briefly before rebounding back to the standard 20% rate.

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Drugs.com

MAY 14, 2024

TUESDAY, May 14, 2024 -- Night shift work can increase a person’s risk of chronic disease, and a new study reveals one possible explanation for this.It appears that just a few days on a night shift schedule throws off body rhythms tied to.

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Science Daily: Pharmacology News

MAY 14, 2024

Astronomers have just discovered WASP-193b, an extraordinarily low-density giant planet orbiting a distant Sun-like star.

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Drugs.com

MAY 14, 2024

TUESDAY, May 14, 2024 -- While some states have moved to severely curb women's access to abortion, including abortion pills, over 8,000 women living in those states are getting the pills by mail each month from states without such.

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Science Daily: Pharmacology News

MAY 14, 2024

A young whale's journey across the Mediterranean highlights the many threats facing ocean animals, researchers say.

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Drugs.com

MAY 14, 2024

TUESDAY, May 14, 2024 -- Vaping rates among U.S. kids in grades 9 through 12 fell to 5% in 2021, the latest year for which data is available. That's down from a peak of 7.2% of teens who vaped in 2019, a new report finds.However, the 5% vaping rate.

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Conversations in Drug Development Trends

MAY 14, 2024

By: Amy Raymond, Derek Ansel, Nathan Chadwick, & Juliane Mills When choosing a CRO for a rare disease study, what truly sets them apart is their methodology: the CRO’s mindset, their approach to each unique study, and their agility in navigating the inherent complexities of rare disease research. The team’s ability to apply insights and proven strategies from their experience in rare disease research brings concepts to reality, getting medications to patients faster.

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Drugs.com

MAY 14, 2024

TUESDAY, May 14, 2024 -- San Francisco is on the verge of passing a ban on "forever chemicals" in the protective clothing firefighters wear while battling blazes.City lawmakers are expected to pass an ordinance on Tuesday that will prohibit.

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BioPharma Drive: Drug Pricing

MAY 14, 2024

The biotechs aim to marry FogPharma’s polypeptide science with Artbio’s lead-based radiopharmaceutical technology in one of the industry’s hottest fields.

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Drugs.com

MAY 14, 2024

TUESDAY, May 14, 2024 -- Melanoma, while rare among Black Americans, is often detected later with devastating consequences, a new study finds.Black people are frequently diagnosed with melanoma at later stages, increasing their risk of death.

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BioPharma Drive: Drug Pricing

MAY 14, 2024

The reduction of 1,500 roles in the first quarter is part of CEO Bill Anderson’s plan to shrink Bayer’s bureaucracy and “radically realign” its culture.

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Drugs.com

MAY 14, 2024

TUESDAY, May 14, 2024 (HeathDay News) -- Following decades of declines, drowning deaths are once again climbing in the United States, new government data shows. More than 4,500 people died from drowning each year in 2020 through 2022, 500 more per.

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BioPharma Drive: Drug Pricing

MAY 14, 2024

The firm, one of the sector’s more active crossover investors, closed the fund during a surge in the financings that bridge biotechs to the public markets.

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thought leadership

MAY 14, 2024

Compiling and submitting a New Drug Application ( NDA) submission is a complicated and intensive activity. Once you have submitted your application to FDA, you may be curious about what can you expect to hear and when. Below are some of the common questions we receive from Sponsors about what to expect during the NDA review process.

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Cytel

MAY 14, 2024

Written by Angela Vinken and Patti Arsenault Key Opinion Leaders (KOLs) — i.e., trusted, well-respected experts — are crucial in clinical research, especially in rare diseases. They have the expertise, network, and experience to add great scientific value to clinical research and can influence and shape the trajectory of clinical research within their professional communities.

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Perficient: Drug Development

MAY 14, 2024

The Summer ‘24 release preview is out and will be generally available by mid-June! The latest release from Salesforce brings critical feature improvements for our friends in the Healthcare & Life Sciences (HLS) industry. Of course, the hot topic in Tech over the last year has been Artificial Intelligence (AI). As Salesforce continues to beef up its AI offerings, the HLS industry using Health Cloud will reap the benefits of new and improved generative AI features that make a substantial diff

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Drug Target Review

MAY 14, 2024

How do hydrophobicity, electrostatic charge, and secondary confirmation of helical polypeptides influence the stimulation of innate immune pathways in antigen-presenting cells (APCs)? These physical properties directly affect physical disruption of membrane integrity, which can activate endoplasmic reticulum (ER) stress to initiate pro-inflammatory signalling specifically in APCs.

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Drug Patent Watch

MAY 14, 2024

Annual Drug Patent Expirations for GAVRETO Gavreto is a drug marketed by Blueprint Medicines and is included in one NDA. It is available from one supplier.

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NIOSH Science Blog: Drugs

MAY 14, 2024

The National Institute for Occupational Safety and Health (NIOSH) Future of Work Initiative hosted a webinar to address the role of work arrangements in the future of work. Among the changes anticipated in the Future of Work is an increasing prevalence of nonstandard work arrangements, such as contingent, platform-based, seasonal, on-call, or other “nonstandard” work.

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