Tue.May 28, 2024

article thumbnail

When should you neuter or spay your dog?

Science Daily: Pharmacology News

A new study updates guidelines for when you should neuter or spay your dog to prevent increased risk of cancer or joint disorders.

328
328
article thumbnail

Nations Fail to Agree on Treaty on Preventing Next Pandemic

Drugs.com

TUESDAY, May 24, 2024 -- Following two years of tough negotiations, efforts to craft a global treaty to help countries fight future pandemics have failed, the World Health Organization has acknowledged."WHO Member States have ended intensive.

264
264
Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

article thumbnail

Genetic mosaicism more common than thought

Science Daily: Pharmacology News

Researchers found that approximately one in 40 human bone marrow cells carry massive chromosomal alterations without causing any apparent disease or abnormality. Even so-called normal cells carry all sorts of genetic mutations, meaning there are more genetic differences between individual cells in our bodies than between different human beings. The discovery was enabled by a single-cell sequencing technology called Strand-seq, a unique DNA sequencing technique that can reveal subtle details of g

DNA 321
article thumbnail

Even a Small Urban Garden Can Boost Your Microbiome

Drugs.com

TUESDAY, May 28, 2024 -- A small urban garden can contribute to your health, especially if the garden contains rich soil, a new study shows.A one-month indoor gardening period increased the bacterial diversity of participants’ skin and appeared to i.

261
261
article thumbnail

Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

article thumbnail

Improved refrigeration could save nearly half of the 1.3 billion tons of food wasted each year globally

Science Daily: Pharmacology News

A new study concludes that nearly half of the food waste, about 620 million metric tons, could be eliminated by fully refrigerated food supply chains worldwide. At the same time, fully refrigerated supply chains, or 'cold chains,' could cut food waste-related emissions of climate-warming greenhouse gases by 41% globally, according to a new study.

319
319

More Trending

article thumbnail

Simple food swaps could cut greenhouse gas emissions from household groceries by a quarter

Science Daily: Pharmacology News

Switching food and drink purchases to very similar but more environmentally friendly alternatives could reduce the greenhouse gas emissions from household groceries by more than a quarter (26%), according to a new study.

315
315
article thumbnail

Epidurals Linked to Better Outcomes After Childbirth

Drugs.com

TUESDAY, May 28, 2024 -- Women who get an epidural during delivery appear to have a marked reduction in serious complications the first few weeks after giving birth, a new study shows.A painkilling epidural can reduce risk by 35% in women for.

241
241
article thumbnail

Florida fossil porcupine solves a prickly dilemma 10-million years in the making

Science Daily: Pharmacology News

An exceptionally rare fossilized porcupine skeleton discovered in Florida has allowed researchers to trace the evolutionary history for one of North America's rarest mammals.

Research 315
article thumbnail

Agios cashes in on cancer drug again with $905M Royalty Pharma deal

BioPharma Drive: Drug Pricing

The deal involves royalties for a brain cancer drug Agios previously sold off and that Royalty Pharma thinks could generate more than $1 billion in U.S. sales.

Drugs 196
article thumbnail

From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

article thumbnail

Researchers have located the brain network responsible for stuttering

Science Daily: Pharmacology News

An international research group succeeded in identifying the probable origin of stuttering in the brain.

Research 301
article thumbnail

CDC Warns Again of Salmonella Tied to Backyard Poultry

Drugs.com

TUESDAY, May 28, 2024 -- Backyard chickens are causing outbreaks of salmonella across the United States, the U.S. Centers for Disease Control and Prevention warns.About 109 people in 29 states have gotten sick from salmonella after touching or.

Disease 189
article thumbnail

Why do Dyeing poison frogs tap dance?

Science Daily: Pharmacology News

The toe tapping behavior of various amphibians has long attracted attention from researchers and pet owners. Despite being widely documented, the underlying functional role is poorly understood. In a new paper, researchers demonstrate that Dyeing poison frogs modulate their taps based on specific stimuli.

Research 283
article thumbnail

Insmed shares double as lung drug data convince Wall Street

BioPharma Drive: Drug Pricing

After reporting positive clinical trial results for its drug brensocatib, Insmed plans to later this year file for U.S. approval in bronchiectasis that’s not associated with cystic fibrosis.

article thumbnail

How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

article thumbnail

How killifish embryos use suspended animation to survive over 8 months of drought

Science Daily: Pharmacology News

The African turquoise killifish lives in ephemeral ponds in Zimbabwe and Mozambique. To survive the annual dry season, the fish's embryos enter a state of extreme suspended animation or 'diapause' for approximately 8 months. Now, researchers have uncovered the mechanisms that enabled the killifish to evolve this extreme survival state.

Research 195
article thumbnail

Roche’s Sabry retires; Duchenne drug fails confirmatory test

BioPharma Drive: Drug Pricing

The veteran executive will be replaced by Boris Zaïtra. Elsewhere, Nippon Shinyaku shared negative Phase 3 data and Merck unveiled new breast cancer results for Keytruda.

Drugs 167
article thumbnail

Bringing back an ancient bird

Science Daily: Pharmacology News

Using ancient DNA extracted from the toe bone of a museum specimen, biologists have sequenced the genome of an extinct, flightless bird called the little bush moa, shedding light into an unknown corner of avian genetic history. The work is the first complete genetic map of the turkey-sized bird whose distant living cousins include the ostrich, emu, and kiwi.

DNA 179
article thumbnail

The future of medicine: AI’s role in uncovering new drugs

BioPharma Drive: Drug Pricing

Artificial intelligence (AI) has sparked a revolution in the pharmaceutical industry, reshaping the way we approach complex biological challenges.

article thumbnail

Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

article thumbnail

Weighted Blankets May Not Help Troubled Children Sleep

Drugs.com

TUESDAY, May 28, 2024 -- Weighted blankets are trendy items, largely based on the idea that the pressure of a heavy blanket will help a person more easily slip into slumber.But they do little to help troubled children sleep better, a new study has.

130
130
article thumbnail

J&J gains another bispecific antibody with $1.25B skin drug buy

BioPharma Drive: Drug Pricing

The deal is J&J’s second this month involving bispecific antibodies, which the company has prioritized to build its immune and cancer drug pipeline.

Drugs 135
article thumbnail

AI Headphones Let Listeners Hear Just One Voice in a Crowd

Drugs.com

TUESDAY, May 28, 2024 -- New AI headphone technology can help people “tune in” to specific folks in a crowd, allowing them to better hear a speaker even in noisy environments.With the system, called “Target Speech Hearing,” a user wearing headpho.

130
130
article thumbnail

Antibodies 101: Designing Your First Flow Panel

addgene Blog

When analyzing your cells using flow cytometry, you are typically measuring the presence or absence of certain markers on the surface or the inside of your cells. While proteins themselves can emit intrinsic fluorescence when excited with ultraviolet (UV) light, they do so via aromatic amino acids found in all proteins, so you can't distinguish the different proteins from each other.

105
105
article thumbnail

Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

article thumbnail

Binge-Eating Disorder Could Be Tougher to Kick Than Thought

Drugs.com

TUESDAY, May 28, 2024 -- Prior studies have suggested that binge eating disorder may not last long, but a more rigorous look at the illness finds that just isn't so.“The big takeaway is that binge-eating disorder does improve with time, but for m.

130
130
article thumbnail

Cover Image

Chemical Biology and Drug Design

Cover Image © molekuul_be/Shutterstock.

100
100
article thumbnail

Perficient @ The 2024 Michigan Kidney Walk

Perficient: Drug Development

On Sunday, May 19th, 2024, 21 individuals consisting of Perficient employees and their family members, participated in the 2024 Michigan Kidney Walk at the Detroit Zoo. This annual event aims to raise funds for the National Kidney Foundation, an organization that provides critical support to those affected by kidney disease. A Tradition of Giving This year marked our third consecutive participation in the Kidney Walk.

Disease 98
article thumbnail

Harnessing natural killer cells to combat age-related diseases

Drug Target Review

How do senescent cells contribute to degenerative diseases, cancer, and immuno-senescence? Senescence is a central hallmark of aging. Telomere damage, epigenetic dysregulation, DNA damage and mitochondrial dysfunction are primary drivers of damage in aging. Several of these drivers of damage can induce senescence. Senescence can in turn drive the consequential clinical hallmarks of aging: stem cell exhaustion, proteomic dysregulation and chronic inflammation.

Disease 78
article thumbnail

Differentiating Your Inflammatory Disease Product: Common Challenges

Cytel

Written by Susannah Sadler and Stacy Grieve Launching a treatment for inflammatory diseases can be a make-or-break endeavor. A robust evidence base and a compelling value story are crucial to success, but current challenges and unexpected bumps in the road will require creative solutions. Here we describe three case study examples of common issues faced in the inflammatory disease space and how these challenges were overcome using novel solutions, ultimately leading sponsors to submission succes

Disease 64
article thumbnail

Which pharmaceutical companies have the most SPCs in Spain?

Drug Patent Watch

This chart shows the pharmaceutical companies with the most supplementary protection certificates (SPCs) in Spain.

article thumbnail

E&C lawmakers grill directors of FDA medical product centers

Agency IQ

BY RACHEL COE, MSC The House E&C Health Subcommittee Hearing on May 22 featured an extensive grilling of the leaders of FDA’s three medical products centers: CDER, CBER and CDRH. Representatives on both sides of the aisle took full advantage of their floor time to probe FDA leadership on its spending, performance and specific regulatory policies – including its recent Laboratory Developed Test final rule.

article thumbnail

New patent expiration for Cephalon drug NUVIGIL

Drug Patent Watch

Annual Drug Patent Expirations for NUVIGIL Nuvigil is a drug marketed by Cephalon and is included in one NDA. It is available from seven suppliers.

Drugs 59