Sat.Jul 01, 2023 - Fri.Jul 07, 2023

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The Growing Role of CROs in Clinical Trials

PPD

It’s estimated that nearly three out of every four clinical trials are conducted by contract research organizations (CROs), highlighting just how much sponsors value — and rely on — the work that CROs perform. As clinical trials become more complex, sponsors are seeking business partnerships with a congruency in the management and prioritization of pipeline.

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Pfizer backs CRISPR biotech Caribou in latest cell therapy investment

BioPharma Drive: Drug Pricing

Five years after helping launch Allogene Therapeutics, Pfizer is backing another developer of “off-the-shelf” cell therapies in a deal that gives the drugmaker the chance to acquire a multiple myeloma treatment.

Therapies 335
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Long-Acting, Injected HIV Meds Can Help Tough-to-Treat Patients

Drugs.com

WEDNESDAY, July 5, 2023 -- For nearly three decades, daily antiretroviral pills have offered patients living with HIV a highly effective way to keep their infection under control. But some patients, particularly those beset by homelessness, drug.

Drugs 328
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Similar to humans, elephants also vary what they eat for dinner every night

Science Daily: Pharmacology News

A detailed analysis of the dietary habits of elephants showed surprising variation from meal to meal, which could have important ramifications for wildlife protection and conservation strategies.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Dutch PanCoroNed and its successor coronavirus Consortium select CDD Vault to manage their research data

Collaborative Drug

Dutch PanCoroNed and its successor coronavirus Consortium select CDD Vault to manage their research data.

Research 238

More Trending

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Learn the Differences Between Hepatitis A, B, C, D & E

Drugs.com

THURSDAY, July 6, 2023 -- Curious about what the differences are between hepatitis A, B, C, D and E? If so, you’ve come to the right place. Here, experts break down hepatitis infection by type to reveal what it is, the most common symptoms, how.

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Potent greenhouse gas produced by industry could be readily abated with existing technologies

Science Daily: Pharmacology News

Researchers have found that one method of reducing greenhouse gas emissions is available, affordable, and capable of being implemented right now. Nitrous oxide, a potent greenhouse gas and ozone-depleting substance, could be readily abated with existing technology applied to industrial sources.

Research 265
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Antibody Drug Conjugates: windows of opportunity

Drug Target Review

Over the last two decades, an increasing number of Antibody Drug Conjugate (ADC) therapeutics have been approved for oncology indications. These therapies have broadened treatment options for patients to expand beyond the more traditional small molecule drug alternatives. Through their unique modes of action, ADCs have been heralded as having the potential to positively impact not only cancer patient outcomes but also quality of life, an increasingly important factor in treatment decisions for t

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With new data, J&J steps forward in growing race for oral autoimmune drugs

BioPharma Drive: Drug Pricing

Phase 2 results show a pill the company is developing is competitive with other oral medicines in testing against psoriasis, among them the TYK2 inhibitors that have drawn significant industry interest.

Drugs 284
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Hepatitis C Treatments: A Comprehensive Guide

Drugs.com

THURSDAY, July 6, 2023 -- Did you know the U.S. Centers for Disease Control and Prevention estimates that there were nearly 68,000 new cases of acute hepatitis C in 2020 and over 107,000 newly reported cases of chronic hepatitis C? To help you.

Treatment 299
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Triple combination therapy brings lasting improvement in cystic fibrosis

Science Daily: Pharmacology News

The mucus in the airways is not as sticky, inflammation in the lungs significantly reduced: Triple combination therapy can achieve these positive, lasting effects in patients with cystic fibrosis (CF). According to new research, this form of medication improves the symptoms of CF in many patients.

Therapies 259
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Expanding the Chemistry of Dihaloacetamides as Tunable Electrophiles for Reversible Covalent Targeting of Cysteines

Covalent Modifiers

Daiki Yamane, Ryo Tetsukawa, Naoki Zenmyo, Kaori Tabata, Yuya Yoshida, Naoya Matsunaga, Naoya Shindo, and Akio Ojida Journal of Medicinal Chemistry 2023 DOI: 10.1021/acs.jmedchem.3c00737 The choice of an appropriate electrophile is crucial in the design of targeted covalent inhibitors (TCIs). In this report, we systematically investigated the glutathione (GSH) reactivity of various haloacetamides and the aqueous stability of their thiol adducts.

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Sarepta sells FDA fast pass earned from Duchenne gene therapy approval

BioPharma Drive: Drug Pricing

The deal enables Sarepta to quickly cash in on the clearance of Elevidys, with $102 million in new funds to help bankroll its drug research.

Therapies 271
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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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New Heart Implant Monitors, Treats -- and Then Dissolves Away

Drugs.com

FRIDAY, July 7, 2023 -- An experimental implant now under development could serve as a temporary monitor and pacemaker for ailing heart patients -- then dissolve away when it’s no longer needed. The soft, lightweight and transparent implant.

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Eliminating extra chromosomes in cancer cells prevent tumor growth

Science Daily: Pharmacology News

Cancer cells with extra chromosomes depend on those chromosomes for tumor growth, a new study reveals, and eliminating them prevents the cells from forming tumors. The findings, said the researchers, suggest that selectively targeting extra chromosomes may offer a new route for treating cancer.

Research 226
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Connect In Pharma 2023 Revealed Latest Trends in Pharmaceutical Manufacturing and Drug Delivery

Drug Discovery Today

London, UK, 28 June 2023 / Sciad Newswire / Hosting leading industry experts from across Europe, Connect in Pharma 2023 revealed future trends in pharma and AI, sustainability, and preventative medicine during a two-day meeting in Geneva on 14 & 15 June.

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What US trial sponsors should know about the GDPR

BioPharma Drive: Drug Pricing

What is the GDPR and why does it matter to your life sciences company. iliomad Health Data can help you maintain GDPR compliance.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Another Enemy on the Front Lines in Ukraine: Antibiotic-Resistant Germs

Drugs.com

TUESDAY, July 4, 2023 -- Bacteria found in hospital patients in Ukraine is showing extreme antibiotic resistance, making it harder to treat the wounded and ill in this war-torn country, new research warns. “I am quite thick-skinned and have.

Hospitals 299
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Growing bio-inspired polymer brains for artificial neural networks

Science Daily: Pharmacology News

A new method for connecting neurons in neuromorphic wetware has been developed. The wetware comprises conductive polymer wires grown in a three-dimensional configuration, done by applying square-wave voltage to electrodes submerged in a precursor solution. The voltage can modify wire conductance, allowing the network to be trained. This fabricated network is able to perform unsupervised Hebbian learning and spike-based learning.

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Register now to visit Lab Innovations 2023

Drug Discovery Today

Secure your ticket for the UK’s largest trade show for the whole lab industry

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Moderna, chasing GSK and Pfizer, brings RSV vaccine to regulators

BioPharma Drive: Drug Pricing

The vaccine has a chance to become Moderna’s second approved product and could help offset declining sales for its COVID-19 shot.

Vaccine 184
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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Taking ADHD Meds Won't Raise a Kid's Odds for Drug Abuse Later: Study

Drugs.com

THURSDAY, July 6, 2023 -- Stimulant medications like Ritalin are commonly prescribed to help treat the symptoms of attention deficit hyperactivity disorder, but there have been concerns the drugs may lay the groundwork for later substance abuse. New.

Drugs 298
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Creative people enjoy idle time more than others

Science Daily: Pharmacology News

For those with creative minds, screen-free downtime can be fruitful and entertaining: Creative people use their idle time by letting one idea lead to another.

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Epigenetic editing: the next generation of genetic medicine

Drug Target Review

When targeted gene editing became a reality more than ten years ago, many people hoped for a revolutionary tsunami of new medical treatments. In the wake of the Human Genome Project, the promise of precision medicine is marching forward, yet the clinic has experienced a mere trickle of new therapeutics so far. The reasons for this are multifaceted, including concerns over the safety of directly altering DNA sequences and subsequent regulatory restrictions that have arisen as a result.

DNA 106
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Brii buys further into VBI therapy, expanding hepatitis B partnership

BioPharma Drive: Drug Pricing

The deal comes three months after VBI cut costs and laid off staff in a restructuring meant to prioritize the two medicines Brii is interested in.

Therapies 176
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Pfizer Warns of Shortage of Antibiotic, Bicillin L-A, Used to Fight Syphilis

Drugs.com

FRIDAY, July 7, 2023 -- Infectious disease experts are warning that a shortage of a key antibiotic for treating the sexually transmitted infection syphilis could make it hard to fight the spread of the disease. The United States already has a big.

Disease 279
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Why there are no kangaroos in Bali (and no tigers in Australia)

Science Daily: Pharmacology News

Researchers are using a new model to clarify why millions of years ago more animal species from Asia made the leap to the Australian continent than vice versa. The climate in which the species evolved played an important role.

Research 214
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Key considerations before commencing cell line development

Drug Target Review

The cell line development stage The cell line development (CLD) stage begins with gene optimisation for high expression, followed by insertion of the genes of interest (GOIs) into a mammalian host cell line. Typically, this will be a Chinese hamster ovary (CHO) cell line, with alternatives such as murine, human and even duck embryonic cell lines having been used.

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‘It’s felt like Groundhog Day’: Biotech IPO slump drags on through 2023

BioPharma Drive: Drug Pricing

Some industry watchers predict activity could soon pick up, as market conditions improve and a mix of cash-strapped startups as well as advanced biotechs test the waters.

Marketing 167