This site uses cookies to improve your experience. To help us insure we adhere to various privacy regulations, please select your country/region of residence. If you do not select a country, we will assume you are from the United States. Select your Cookie Settings or view our Privacy Policy and Terms of Use.
Cookie Settings
Cookies and similar technologies are used on this website for proper function of the website, for tracking performance analytics and for marketing purposes. We and some of our third-party providers may use cookie data for various purposes. Please review the cookie settings below and choose your preference.
Used for the proper function of the website
Used for monitoring website traffic and interactions
Cookie Settings
Cookies and similar technologies are used on this website for proper function of the website, for tracking performance analytics and for marketing purposes. We and some of our third-party providers may use cookie data for various purposes. Please review the cookie settings below and choose your preference.
Strictly Necessary: Used for the proper function of the website
Performance/Analytics: Used for monitoring website traffic and interactions
Tackling HIV continues to be a major public health challenge, mainly because the persistence of viral reservoirs means that people living with HIV need to take lifelong antiretroviral treatment. But some individuals, known as 'post-treatment controllers,' are able to maintain an undetectable viral load even after stopping treatment.
Skip to main content CONTINUE TO SITE ➞ Dont miss tomorrows biopharma industry news Let BioPharma Dives free newsletter keep you informed, straight from your inbox. in 2013 — the field has taken off since the success of Novartis’ prostate cancer treatment Pluvicto. The drug earned Novartis more than $1.3
Drugging such undruggable targets is essential to develop new therapies for diseases where current treatment options are limited or nonexistent. Tomonori Tamura, Masaharu Kawano, and Itaru Hamachi Chemical Reviews 2024 DOI: 10.1021/acs.chemrev.4c00745
25, 2023 -- If you're contemplating breast cancer surgery, searching online for information may not be the best way to learn about your treatment options. WEDNESDAY, Oct. Educational materials on breast cancer surgery often vary.
THURSDAY, May 9, 2024 -- A tiny, flexible device that wraps around the spinal cord could be a breakthrough in the treatment of spinal injuries.The device, developed by a University of Cambridge team, can record 360-degree information and provide a.
The findings provide new insights that could help inform therapeutic treatments regarding mental health and drug addiction. A new study is among the first of its kind to separate activity relating to emotion generation from emotion regulation in the human brain.
Skip to main content Dont miss tomorrows biopharma industry news Let BioPharma Dives free newsletter keep you informed, straight from your inbox. This shift raises ethical questions around prioritizing supply for diabetes patients versus those seeking treatment for obesity or cosmetic weight loss. All copyright resides with them.
A tiny, flexible electronic device that wraps around the spinal cord could represent a new approach to the treatment of spinal injuries, which can cause profound disability and paralysis. Unlike current approaches, the new devices can record 360-degree information, giving a complete picture of spinal cord activity.
While two approved treatments, pirfenidone and nintedanib, slow disease progression, there currently is no treatment that reverses the effects or offers a cure for IPF. However, recent advancements and strategic approaches in clinical trials offer hope that additional treatments are on the way. It’s not for lack of trying.
Scientists have rebuilt, in laboratory glassware, the neural pathway that sends information from the body's periphery to the brain, promising to aid research on pain disorders.
The results pave the way for future single-cell or spatially resolved studies that look at how cells surrounding a metastatic tumor impact its progression or treatment outcomes. Eventually, we hope that these methods can help inform the development of drugs or even guide patients’ individual treatments.”
The Expanding Role of mRNA in Cancer Therapy One of the most exciting applications of mRNA therapeutics lies in cancer treatment, where leveraging the immune system to target tumors offers a novel approach. These findings underscore the potential of mRNA to redefine cancer treatment by offering precise, patient-specific therapies.
Kendal Chidwick NDARC’s Kendal Chidwick discusses the findings from a recently published study that examined how patterns of opioid agonist treatment medicines have changed over the past decade. Other changes around this time aimed at improving treatment accessibility included increased use of take-home doses and telehealth appointments.
Reston, VA—A novel imaging approach, 68Ga-pentixafor PET/CT, has been shown to accurately identify sub-types of primary aldosteronism (an adrenal gland disorder), outperforming traditional methods for diagnosis.
However, he believes that these fears will dissipate as pharma companies come to realise that AI firms like Unlearn adhere to stringent data control measures, ensuring the ethical use of patient information. In 2025, I think well see breakthroughs that allow us to make significant advances in rare diseases, where the data is small.
In an interview with our team, Delpassand shared his perspective on how targeted radiopharmaceuticals are reshaping cancer treatment and what lies ahead for this evolving field. This dual role enables him to bridge research and clinical practice, ensuring scientific innovation is directly informed by patient care. “As
Susceptibility or risk biomarkers can detect the likelihood of a patient developing a disease or medical condition, which is crucial for treatments that are most effective before the onset of symptoms. A biomarker is a measurable indicator of a biological process, disease state, or response to a treatment.
On Sunday, it was disclosed that additional, likely on-target adverse findings were observed in a primate GLP study on long-term treatment with Merck’s second-generation LRRK2 inhibitors. Drug Hunter Premium is drug discovery, distilled, so you can quickly catch up and make informed decisions based on industry examples.
Their findings may result in new treatments for reproductive conditions. He stated that this could inform new treatments for reproductive conditions like recurrent pregnancy loss and preeclampsia. A human foetus contains genetic material from both parents, which makes it partly foreign to the pregnant person’s body.
This breakthrough led to the development and approval of sotorasib (AMG510) and adagrasib (MRTX849), revolutionizing the treatment of KRASG12C-dependent lung cancer. Insights from successful KRASG12C targeting informed the design of molecules addressing other mutations, often in a covalent manner.
The study opens the door to new treatments and preventive measures for bone regeneration and osteoporosis research. A new study of the PhyloBone project of the University of Turku, Finland, identifies hundreds of non-collagenous proteins in the bone matrix that may play regulatory roles in bone formation and regeneration.
While RA therapies targeted to specific inflammatory pathways have emerged, only some patients’ symptoms improve with treatment, emphasizing the need for multiple treatment approaches tailored to different disease subtypes. They also found that patients’ CTAPs were dynamic and could change over time in response to treatment.
Molecular-level biochemical assays like transcriptomics, genomics and proteomics have emerged as valuable tools for identifying potential targets in cancer treatment through deep cyclic inhibition (DCI). Importantly, transcriptomics information shows that certain aspects of a disease change the gene expression profile.
By: Simran Padam, Medical Director, Medical Affairs Personalized treatment approaches have emerged as pivotal in improving outcomes for hematological cancers. Hematological cancer cells can also develop resistance to therapies over time, reducing treatment effectiveness.
Revolutionizing Treatment Through the Skin with Transdermal Drug Delivery Systems The human skin, often perceived as a passive barrier to the external environment, holds potential as a route for drug administration. These fluctuations can lead to unwanted side effects or compromise the effectiveness of the treatment.
Thus, UCHL1 inhibitors could serve as a viable treatment strategy against these aggressive cancers. Additionally, we report a ligand-bound crystal structure of the most potent molecule in complex with UCHL1, providing insight into the binding mode and information for future optimization.
Clear and accessible communication methods help patients understand their health information, engage with their care, and make informed decisions. Clear and accessible communication ensures that all patients receive the information they need in a format they can understand, which is crucial for delivering equitable and effective care.
This single-cell localization could pinpoint a proteins location in a specific cancer cell after treatment, for instance. This computer vision model looks at three stained images of a cell to gather information about the state of that cell, such as its type, individual features, and whether it is under stress. Then PUPS does the rest.
mCRPC is a particularly aggressive form of the disease, and patients currently have limited treatment options,” said Eleni. “As The dual approach represents an effort to expand treatment efficacy across a broader subset of tumours, potentially improving outcomes. “In
2] The label also has a warning about liver toxicity and the need to monitor liver blood tests at baseline and then monthly for at least six months after initiating treatment with fitusiran or after a dose increase of fitusiran. [2] Fitusiran 1711.0g/mol, 1] It is an antithrombin-directed small interfering ribonucleic acid. [1] 26 March 2025.
The updated label reflects the evolving role of amyloid imaging in both diagnosis and treatment planning, acknowledging its importance not only in identifying disease presence but also in selecting patients likely to benefit from disease-modifying therapies that target amyloid pathology.
At a busy research site, a clinical trial is ready to launch but its stuck in limbo over a single paragraph in the informed consent form (ICF). While the trial waits for approval, patients who are eager for a new treatment face delay. Language relating to the potential cost of participation.
Universal design (UD) in healthcare ensures that facilities, services, and information are accessible to everyone, regardless of their physical abilities. This approach encompasses architectural designs, patient communication methods, and even the format of health information.
By incorporating visual aids into the healthcare environment, providers can help ensure that all patients receive clear, comprehensible information about their health. Here’s how to effectively implement visual aids: The Importance of Visual Aids Visual aids enhance the communication process by providing visual representations of information.
Individuals with cognitive disabilities may face challenges in understanding information, communicating, and navigating complex healthcare systems. Avoid medical jargon and use plain language to explain health conditions, treatments, and procedures. Visual aids can help patients understand complex information more easily.
With 20-25% of the global population affected by metabolic problems, finding effective treatments is crucial for cardiovascular and metabolic (CVM) conditions. Traditional study designs feature predetermined sample sizes, assessments, and analyses that must remain in place over long treatment durations.
Drug development faces significant challenges: long timelines, high costs , complex processes and low probabilities of success (PoS), exacerbated by the shift towards more complex molecules, biologics and cell and gene therapies, hindering patient access to vital treatments. Highly accurate protein structure prediction for the human proteome.
png Listing Introduction In todays patient-centric landscape, precision-driven omnichannel strategies are essential for engaging HCPs within the critical treatment decision window to effectively improve patient outcomes. Listing Image Diaceutics_ListingLogo_250x190.png
This study explored the effects of beginning treatment with lower starting doses of MariTide to improve tolerability while maintaining clinical benefit. These results were evaluated using the efficacy estimand, a statistical model that accounts for treatment adherence and protocol deviations.
This work is driven by necessity to generate enough information for drug development companies to consider the disease as a therapeutic target in their pipeline. As a result, rare disease communities have a more connected and informed network. Why Is There an Increase in Patient-Led Rare Disease Research?
Today, we kick off the series with the first principle: Provide Multiple Means of Representation The Importance of Representation Imagine walking into a healthcare facility where the instructions and important information are only provided verbally. This allows patients to read along as the information is presented verbally.
Its sodium salt is used for the treatment of generalised myasthenia gravis (a disease that leads to muscle weakness and tiredness) in adults whose immune system produces antibodies against acetylcholine receptors. Retrieved 11 December 2023. ^ “Zilbrysq Product information” Union Register of medicinal products. April 2018).
It allows us to make more informed decisions and identify opportunities that may have been overlooked using traditional methods.” Conducting Due Diligence Once potential targets are identified, thorough due diligence is crucial to validate the assessment and make informed in-licensing decisions.
Reduced Dependence: Patients can access information and services without relying heavily on others, fostering a sense of autonomy and self-reliance. Active Participation: Effective communication enables patients to actively participate in their healthcare decisions, leading to better engagement and adherence to treatment plans.
We organize all of the trending information in your field so you don't have to. Join 15,000+ users and stay up to date on the latest articles your peers are reading.
You know about us, now we want to get to know you!
Let's personalize your content
Let's get even more personalized
We recognize your account from another site in our network, please click 'Send Email' below to continue with verifying your account and setting a password.
Let's personalize your content