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Finding the right CDMO partner for cell line development

Drug Target Review

Together, these attributes provide a strong foundation for protein expression with enough adaptability to produce much of the commercial and therapeutic protein market. Skilled CDMOs can also locate or create favourable genomic microenvironments where transcription factors are efficiently recruited, further boosting protein production.

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Targeting a human protein may stop Ebola virus in its tracks

The Pharma Data

To treat Ebola virus infections, researchers are taking a close look at a key piece of the virus: polymerase. Polymerase is a viral protein that directs how Ebola virus replicates its genome as it infects new hosts. Drugs that target polymerase could potentially treat Ebola virus infections and save lives.

Virus 52
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Series A Financing of 570 Million Yen Procured by Epsilon Molecular Engineering: A Next-Generation Medium Sized Molecular Biotechnology-Based Drug Discovery Firm

The Pharma Data

Using the obtained sequencing data, Kao Corporation was able to produce an antibody sample in one week using protein production technology such as enzymes cultivated by our technology. Comment from Fumiharu Muroga, Growth Manager at Real Tech Fund] “Proteins are an important structural component of living things.

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Gene editing extends lifespan in mouse model of prion disease

Broad Institute

His lab had just developed base editing, a gene-editing approach that makes single-letter changes in DNA and can shut down protein production using strategies including installing a stop signal in the genetic code. They then administered the AAVs to mice infected with the human prion protein.

Disease 144
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Codon Digest: Bacteria Resist Every Virus

Codon

Peroxisomal metabolic coupling improves fatty alcohol production from sole methanol in yeast. Optogenetic closed-loop feedback control of the unfolded protein response optimizes protein production. How to build a virus-proof cell. Metabolic Engineering. ACS Synthetic Biology. Bundell S & Howe NP.

Virus 52
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Cave Coronavirus in Wuhan Lab Seeded COVID – The Truth Has Always Been Out There, in the Genetics

PLOS: DNA Science

The virus SARS-CoV-2 emerged in Wuhan, home of a premiere research institute that focuses on viruses. An altered virus could have escaped. Evidence that the virus emerged, or escaped, from the wildlife trade is lacking. Her points: 1. Coincidence? I’ve never thought so. RaTG13 shares about 96.1%

Virus 52
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Dyadic International Rebrands as Dyadic Applied BioSolutions

The Pharma Data

The C1 expression platform , originally derived from a fungus used in industrial enzyme production, has been optimized by Dyadic for robust, scalable, and cost-efficient protein production. Its counterpart, the Dapibus™ platform , is designed for producing proteins in a non-GMP environment for food and industrial use.