2016 - Drug Discovery Digest

First biologic approved in Scotland for hidradenitis suppurativa since 2016

Drug Discovery World

FEBRUARY 16, 2024

The post First biologic approved in Scotland for hidradenitis suppurativa since 2016 appeared first on Drug Discovery World (DDW).

Licensing

Licensing Licensing Treatment Disease

Deaths from Excessive Alcohol Use in the US, 2016-2021

Common Sense for Drug Policy Blog

MARCH 4, 2024

Deaths from Excessive Alcohol Use in the US, 2016-2021 "From 2016–2017 to 2020–2021, the average annual number of U.S. deaths from excessive alcohol use increased by more than 40,000 (29%), from approximately 138,000 per year (2016–2017) to 178,000 per year (2020–2021). MMWR Morb Mortal Wkly Rep 2024;73:154–161.

US Cocaine Seizure Effectiveness Rate, 2016-2020

Common Sense for Drug Policy Blog

JULY 16, 2023

US Cocaine Seizure Effectiveness Rate, 2016-2020 " Methodology and Limitations "Seizure data are obtained from OFO administrative records and is considered reliable. Available Data and Discussion "Total seizures dropped to 19,000 kilograms in 2019, the lowest in the 2016-2020 period and down 35 percent from the 2016 to 2019 average.

Government

Government Production Drugs

2016 to 2019 Saw Increase in Prepregnancy Obesity in U.S.

The Pharma Data

NOVEMBER 25, 2020

2016 to 2019 Saw Increase in Prepregnancy Obesity in U.S. 25, 2020 — From 2016 to 2019, there was an increase in prepregnancy obesity in the United States, according to a November data brief published by the U.S. percent in 2016 to 29.0 percent in 2016 to 29.0 Professional. WEDNESDAY, Nov. Driscoll, Ph.D.,

Disease

Disease Research

Bio-Techne Announces ISO 13485:2016 Certification for the Woburn, MA Manufacturing Facility

The Pharma Data

OCTOBER 14, 2020

15, 2020 /PRNewswire/ — Bio-Techne Corporation (NASDAQ: TECH), a leading provider of proteins, antibodies and cytokines today announced that its Woburn, Massachusetts site received ISO 13485:2016 certification for Medical Device and Quality Management Systems. MINNEAPOLIS , Oct. ” About Bio-Techne Corporation (NASDAQ: TECH).

International

International Therapies Production Science

Trial to test monoclonal antibody for virus of growing concern

Drug Discovery World

JULY 2, 2024

The US Centers for Disease Control and Prevention (CDC) identified increases in AFM cases in 2014, 2016, and 2018. AFM has emerged in the United States with spikes in cases every other year, primarily in the late-summer months over the last decade.

Virus

Virus Trials Clinical Trials Laboratories

Cases of Drug-Resistant Gonorrhea Have Tripled in China, Posing a Global Threat

Drugs.com

MARCH 28, 2024

THURSDAY, March 28, 2024 -- A strain of highly antibiotic-resistant gonorrhea first emerged in China in 2016, and cases of this tough-to-treat infection have tripled there in just five years, Chinese researchers report. It's a warning to the rest.

Drugs

Drugs Research

AI-driven drug company secures $372m Series D funding

Drug Discovery World

JULY 1, 2024

To address this bottleneck, Formation Bio (launched in 2016 as TrialSpark) has built technology platforms, processes, and capabilities with the aim of accelerating drug development and clinical trials. ” Advancements in AI are creating more candidate drugs than the industry can progress.

Pharma Companies

Pharma Companies Licensing Licensing Drugs

U.S. Deaths Linked to Alcohol Keep Rising, Especially Among Women

Drugs.com

FEBRUARY 29, 2024

Between 2016 and 2021 (the latest numbers available), "the average number of U.S. THURSDAY, Feb. 29, 2024 -- Deaths where alcohol played a key role climbed sharply in recent years, hitting women even harder than men, new government data shows.

Government

Possible adulticidal drugs for Onchocerca volvulus

Drug Target Review

SEPTEMBER 21, 2023

The findings supported the possibility put forward by Cotton et al (2016) concerning the chance of repurposing these drugs for adulticidal treatment. Possible adulticidal drugs- something to ponder on Cotton et al (2016) made an important discovery when they sequenced the entire genome of O. The research showed that exposing O.

Drugs

Drugs Treatment Disease Research

In Mississippi, a Huge Jump in Cases of Babies Born With Syphilis

Drugs.com

SEPTEMBER 21, 2023

21, 2023 -- The United States is experiencing an alarming wave of congenital syphilis, and one southern state saw a 1,000% rise in babies born with the infection between 2016 and 2022. THURSDAY, Sept. The number of babies born with the infection in.

You're Far Less Likely to Get an Opioid Now After Surgery

Drugs.com

DECEMBER 11, 2023

doctors had already cut the amount of opioids they gave patients after surgery by 2022 to just a third of the amount given in 2016, new research shows.Much of the. MONDAY, Dec. 11, 2023 -- In response to the ongoing crisis of opioid misuse, U.S.

Doctors

Doctors Research

Merck and Moderna to develop a personalised cancer vaccine

Drug Discovery World

OCTOBER 14, 2022

We have been collaborating with Merck on PCVs since 2016, and together we have made significant progress in advancing mRNA-4157 as an investigational personalised cancer treatment used in combination with KEYTRUDA,” said Stephen Hoge, President of Moderna.

Vaccine

Vaccine Research Laboratories Laboratories Clinical Development

U.S. Gender-Affirming Surgeries Nearly Tripled in 3 Years

Drugs.com

AUGUST 23, 2023

23, 2023 -- The number of Americans undergoing gender-affirming surgery is on the rise, new research reveals, almost tripling between 2016 and 2019 alone. WEDNESDAY, Aug. During that period, more than 48,000 patients -- about half of them between 19.

Research

TBD

Broad Institute

AUGUST 31, 2023

TBD By lcopelan@broadinstitute.org August 31, 2023 Yuhan Hao Neptune Bio Related Resources [link] MIA About Current Schedule Video Playlist Resources All talks Contact us MIA Talks Search - Any - Spring 2023 Fall 2022 Spring 2022 Fall 2021 Spring 2021 Fall 2020 Spring 2020 Fall 2019 Spring 2019 Fall 2018 Spring 2018 Fall 2017 Spring 2017 Fall 2016 (..)

Evotec and BMS enter drug discovery licence agreement

Drug Discovery World

JULY 11, 2023

Evotec and BMS originally entered their neurodegeneration partnership in 2016. The agreement covers selected late-stage discovery programmes that were developed and progressed within the collaboration between the two companies. The initial partnership generated a promising pipeline of discovery to clinical-stage programmes.

Licensing

Licensing Licensing Drugs Disease

Moderna sues Pfizer/BioNTech over Covid patent

Drug Discovery World

AUGUST 31, 2022

The lawsuits, which were made in the United States and Germany, state that Pfizer and BioNTech’s Covid-19 vaccine Comirnaty infringes Moderna’s patents for its mRNA technology filed between 2010 and 2016. They are related to the earlier cases of Moderna’s patented technologies which were clinically tested in 2015 and 2016.

Vaccine

Vaccine RNA Licensing Licensing

Growth in New/Novel Psychoactive Substances

Common Sense for Drug Policy Blog

JUNE 17, 2024

Between 2016 and 2022, typically around 50 new psychoactive substances appeared on the market for the first time each year; this fell to 26 in 2023. In addition, around 400 previously reported new substances are detected on the market each year."

Marketing

Marketing Drugs

‘Ice Bucket Challenge’ funds FDA-approved ALS treatment

Drug Discovery World

OCTOBER 4, 2022

In June 2016, the Association provided Amylyx, the producer of AMX0035, with a $750,000 grant for a clinical trial pilot. Then in July 2016, the Association provided the Northeast ALS Consortium (NEALS) with a $1.46 We still have a lot of work to do to cure ALS, but this new treatment is a significant step in that fight.” .

FDA Approval

FDA Approval FDA Treatment Clinical Trials

Auburn University hosts the 60th edition of the Renowned Computational Biophysics Workshop

SCIENMAG: Medicine & Health

AUGUST 18, 2023

For the first time since 2016, the southern USA was home to the “Hands-On Workshop on Computational Biophysics” with Auburn University, for the first […]

Science

Alpha Missense

Broad Institute

MARCH 7, 2024

Alpha Missense By lcopelan@broadinstitute.org March 7, 2024 Jun Cheng MIA About Current Schedule Video Playlist Resources All talks Contact us MIA Talks Search - Any - Spring 2024 Fall 2023 Spring 2023 Fall 2022 Spring 2022 Fall 2021 Spring 2021 Fall 2020 Spring 2020 Fall 2019 Spring 2019 Fall 2018 Spring 2018 Fall 2017 Spring 2017 Fall 2016 Spring (..)

The Market for Image and Performance Enhancing Drugs (IPEDs)

Common Sense for Drug Policy Blog

JUNE 6, 2024

2015 ), with raw powders imported from ‘producer’ countries like China, Egypt, Greece, Thailand, Turkey, and India (Antonopoulos and Hall 2016 ; Brennan et al. As a result, the authors describe the online IPED market as ‘decentralized, highly flexible with no hierarchies, and open to anyone’ (Antonopoulos and Hall 2016 : 708).

Marketing

Marketing Drugs Production Pharmaceuticals

Postdoc flash talks

Broad Institute

FEBRUARY 15, 2024

Postdoc flash talks By lcopelan@broadinstitute.org February 15, 2024 MIA About Current Schedule Video Playlist Resources All talks Contact us MIA Talks Search - Any - Spring 2024 Fall 2023 Spring 2023 Fall 2022 Spring 2022 Fall 2021 Spring 2021 Fall 2020 Spring 2020 Fall 2019 Spring 2019 Fall 2018 Spring 2018 Fall 2017 Spring 2017 Fall 2016 Spring (..)

TBD

Broad Institute

FEBRUARY 12, 2024

TBD By lcopelan@broadinstitute.org February 12, 2024 Julia Salzman MIA About Current Schedule Video Playlist Resources All talks Contact us MIA Talks Search - Any - Spring 2024 Fall 2023 Spring 2023 Fall 2022 Spring 2022 Fall 2021 Spring 2021 Fall 2020 Spring 2020 Fall 2019 Spring 2019 Fall 2018 Spring 2018 Fall 2017 Spring 2017 Fall 2016 Spring 2016 (..)

TBD

Broad Institute

FEBRUARY 12, 2024

TBD By lcopelan@broadinstitute.org February 12, 2024 Tavor Baharav MIA About Current Schedule Video Playlist Resources All talks Contact us MIA Talks Search - Any - Spring 2024 Fall 2023 Spring 2023 Fall 2022 Spring 2022 Fall 2021 Spring 2021 Fall 2020 Spring 2020 Fall 2019 Spring 2019 Fall 2018 Spring 2018 Fall 2017 Spring 2017 Fall 2016 Spring 2016 (..)

Alpha Missense

Broad Institute

JANUARY 29, 2024

Alpha Missense By lcopelan@broadinstitute.org January 29, 2024 Žiga Avsec Google DeepMind MIA About Current Schedule Video Playlist Resources All talks Contact us MIA Talks Search - Any - Spring 2024 Fall 2023 Spring 2023 Fall 2022 Spring 2022 Fall 2021 Spring 2021 Fall 2020 Spring 2020 Fall 2019 Spring 2019 Fall 2018 Spring 2018 Fall 2017 Spring 2017 (..)

TBD

Broad Institute

JANUARY 29, 2024

TBD By lcopelan@broadinstitute.org January 29, 2024 Jose Alquicira-Hernandez MIA About Current Schedule Video Playlist Resources All talks Contact us MIA Talks Search - Any - Spring 2024 Fall 2023 Spring 2023 Fall 2022 Spring 2022 Fall 2021 Spring 2021 Fall 2020 Spring 2020 Fall 2019 Spring 2019 Fall 2018 Spring 2018 Fall 2017 Spring 2017 Fall 2016 (..)

Protein Structure Prediction (TBD)

Broad Institute

JANUARY 29, 2024

Protein Structure Prediction (TBD) By lcopelan@broadinstitute.org January 29, 2024 Sergey Ovchinnikov MIA About Current Schedule Video Playlist Resources All talks Contact us MIA Talks Search - Any - Spring 2024 Fall 2023 Spring 2023 Fall 2022 Spring 2022 Fall 2021 Spring 2021 Fall 2020 Spring 2020 Fall 2019 Spring 2019 Fall 2018 Spring 2018 Fall 2017 (..)

TBD

Broad Institute

JANUARY 29, 2024

TBD By lcopelan@broadinstitute.org January 29, 2024 Joshua Meier MIA About Current Schedule Video Playlist Resources All talks Contact us MIA Talks Search - Any - Spring 2024 Fall 2023 Spring 2023 Fall 2022 Spring 2022 Fall 2021 Spring 2021 Fall 2020 Spring 2020 Fall 2019 Spring 2019 Fall 2018 Spring 2018 Fall 2017 Spring 2017 Fall 2016 Spring 2016 (..)

Valid hypothesis testing after clustering

Broad Institute

JANUARY 29, 2024

Valid hypothesis testing after clustering By lcopelan@broadinstitute.org January 29, 2024 Yiqun Chen MIA About Current Schedule Video Playlist Resources All talks Contact us MIA Talks Search - Any - Spring 2024 Fall 2023 Spring 2023 Fall 2022 Spring 2022 Fall 2021 Spring 2021 Fall 2020 Spring 2020 Fall 2019 Spring 2019 Fall 2018 Spring 2018 Fall 2017 (..)

Tensor factorization (TBD)

Broad Institute

JANUARY 29, 2024

Tensor factorization (TBD) By lcopelan@broadinstitute.org January 29, 2024 Neriman Tokcan UMass Boston MIA About Current Schedule Video Playlist Resources All talks Contact us MIA Talks Search - Any - Spring 2024 Fall 2023 Spring 2023 Fall 2022 Spring 2022 Fall 2021 Spring 2021 Fall 2020 Spring 2020 Fall 2019 Spring 2019 Fall 2018 Spring 2018 Fall (..)

Valid hypothesis testing after clustering

Broad Institute

JANUARY 29, 2024

Valid hypothesis testing after clustering By lcopelan@broadinstitute.org January 29, 2024 Lucy Gao University of British Columbia, Department of Statistics MIA About Current Schedule Video Playlist Resources All talks Contact us MIA Talks Search - Any - Spring 2024 Fall 2023 Spring 2023 Fall 2022 Spring 2022 Fall 2021 Spring 2021 Fall 2020 Spring 2020 (..)

Unemployment and underemployment significant drivers of suicide: Analysis

SCIENMAG: Medicine & Health

JULY 12, 2023

A study examining unemployment and underemployment figures and suicide rates in Australia has found both were significant drivers of suicide mortality between 2004-2016.

Research

TBD

Broad Institute

JANUARY 29, 2024

TBD By lcopelan@broadinstitute.org January 29, 2024 Aparna Nathan Raychaudhuri Lab, Division of Genetics/Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital; Department of Biomedical Informatics, Harvard Medical School MIA About Current Schedule Video Playlist Resources All talks Contact us MIA Talks Search - Any - Spring 2024 Fall (..)

Medical Schools

Medical Schools Hospitals

Anti-ageing therapeutics company completes seed funding

Drug Discovery World

FEBRUARY 28, 2023

Here at FAB our proprietary approach aims to overcome this fundamental challenge to human health as we work to discover and develop new drugs for age-associated diseases.” Founded in 2016 by three experienced entrepreneurs, FAB is currently based in purpose-built lab facilities on the Babraham Research Campus, Cambridge.

Small Molecule

Small Molecule Disease Science Treatment

Protein Design with Deep Learning: Progress, Challenges, and Next Steps

Broad Institute

MAY 6, 2024

MIA About Current Schedule Video Playlist Resources All talks Contact us MIA Talks Search - Any - Spring 2024 Fall 2023 Spring 2023 Fall 2022 Spring 2022 Fall 2021 Spring 2021 Fall 2020 Spring 2020 Fall 2019 Spring 2019 Fall 2018 Spring 2018 Fall 2017 Spring 2017 Fall 2016 Spring 2016 Fall 2015 Summer 2015 Spring 2015 Spring 2014 Fall 2014

On fitness models and the modeling of pandemic evolution

Broad Institute

JANUARY 5, 2024

MIA About Current Schedule Video Playlist Resources All talks Contact us MIA Talks Search - Any - Spring 2024 Fall 2023 Spring 2023 Fall 2022 Spring 2022 Fall 2021 Spring 2021 Fall 2020 Spring 2020 Fall 2019 Spring 2019 Fall 2018 Spring 2018 Fall 2017 Spring 2017 Fall 2016 Spring 2016 Fall 2015 Summer 2015 Spring 2015 Spring 2014 Fall 2014

Multimodal protein language models for deciphering protein function

Broad Institute

MAY 23, 2024

MIA About Current Schedule Video Playlist Resources All talks Contact us MIA Talks Search - Any - Spring 2024 Fall 2023 Spring 2023 Fall 2022 Spring 2022 Fall 2021 Spring 2021 Fall 2020 Spring 2020 Fall 2019 Spring 2019 Fall 2018 Spring 2018 Fall 2017 Spring 2017 Fall 2016 Spring 2016 Fall 2015 Summer 2015 Spring 2015 Spring 2014 Fall 2014

Medical Schools

Medical Schools Research Drugs

Diffusion models

Broad Institute

OCTOBER 2, 2023

Diffusion models By lcopelan@broadinstitute.org October 2, 2023 Sarah Alamdari MIA About Current Schedule Video Playlist Resources All talks Contact us MIA Talks Search - Any - Fall 2023 Spring 2023 Spring 2024 Fall 2022 Spring 2022 Fall 2021 Spring 2021 Fall 2020 Spring 2020 Fall 2019 Spring 2019 Fall 2018 Spring 2018 Fall 2017 Spring 2017 Fall 2016 (..)

Evidence on Safe Consumption Sites

Common Sense for Drug Policy Blog

NOVEMBER 7, 2023

Evidence on Safe Consumption Sites "SCS are a core part of a public health response to an unprecedented poisoning epidemic that has resulted in 36,442 opioid toxicity deaths between January 2016 and December 2022, driven largely by the production and trafficking of novel illegally manufactured opioids (Public Health Agency of Canada, 2021 ).

Production

Production Treatment Drugs Research

TBD

Broad Institute

SEPTEMBER 15, 2023

TBD By lcopelan@broadinstitute.org September 15, 2023 Stanley Hua University of Toronto MIA About Current Schedule Video Playlist Resources All talks Contact us MIA Talks Search - Any - Fall 2023 Spring 2023 Spring 2024 Fall 2022 Spring 2022 Fall 2021 Spring 2021 Fall 2020 Spring 2020 Fall 2019 Spring 2019 Fall 2018 Spring 2018 Fall 2017 Spring 2017 (..)

TBD

Broad Institute

SEPTEMBER 15, 2023

TBD By lcopelan@broadinstitute.org September 15, 2023 Jiaqi Zhang MIA About Current Schedule Video Playlist Resources All talks Contact us MIA Talks Search - Any - Fall 2023 Spring 2023 Spring 2024 Fall 2022 Spring 2022 Fall 2021 Spring 2021 Fall 2020 Spring 2020 Fall 2019 Spring 2019 Fall 2018 Spring 2018 Fall 2017 Spring 2017 Fall 2016 Spring 2016 (..)

TBD

Broad Institute

SEPTEMBER 21, 2023

TBD By lcopelan@broadinstitute.org September 21, 2023 Noor Youssef Debora Marks/ Harvard Medical School/ Systems Biology MIA About Current Schedule Video Playlist Resources All talks Contact us MIA Talks Search - Any - Fall 2023 Spring 2023 Spring 2024 Fall 2022 Spring 2022 Fall 2021 Spring 2021 Fall 2020 Spring 2020 Fall 2019 Spring 2019 Fall 2018 (..)

Medical Schools

First biologic approved in Scotland for hidradenitis suppurativa since 2016

Deaths from Excessive Alcohol Use in the US, 2016-2021

Trending Sources

US Cocaine Seizure Effectiveness Rate, 2016-2020

2016 to 2019 Saw Increase in Prepregnancy Obesity in U.S.

Bio-Techne Announces ISO 13485:2016 Certification for the Woburn, MA Manufacturing Facility

Archive

Trial to test monoclonal antibody for virus of growing concern

Cases of Drug-Resistant Gonorrhea Have Tripled in China, Posing a Global Threat

AI-driven drug company secures $372m Series D funding

U.S. Deaths Linked to Alcohol Keep Rising, Especially Among Women

Possible adulticidal drugs for Onchocerca volvulus

In Mississippi, a Huge Jump in Cases of Babies Born With Syphilis

You're Far Less Likely to Get an Opioid Now After Surgery

Merck and Moderna to develop a personalised cancer vaccine

U.S. Gender-Affirming Surgeries Nearly Tripled in 3 Years

TBD

Evotec and BMS enter drug discovery licence agreement

Moderna sues Pfizer/BioNTech over Covid patent

Growth in New/Novel Psychoactive Substances

‘Ice Bucket Challenge’ funds FDA-approved ALS treatment

Auburn University hosts the 60th edition of the Renowned Computational Biophysics Workshop

Alpha Missense

The Market for Image and Performance Enhancing Drugs (IPEDs)

Postdoc flash talks

TBD

TBD

Alpha Missense

TBD

Protein Structure Prediction (TBD)

TBD

Valid hypothesis testing after clustering

Tensor factorization (TBD)

Valid hypothesis testing after clustering

Unemployment and underemployment significant drivers of suicide: Analysis

TBD

Anti-ageing therapeutics company completes seed funding

Protein Design with Deep Learning: Progress, Challenges, and Next Steps

On fitness models and the modeling of pandemic evolution

Multimodal protein language models for deciphering protein function

Diffusion models

Evidence on Safe Consumption Sites

TBD

TBD

TBD

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