Drug Target Review

NOVEMBER 1, 2023

2 Implication of ATX in a large range of human diseases have been highlighted by both fundamental research and clinical trials. 1-5 Implication of ATX in a large range of human diseases have been highlighted by both fundamental research and clinical trials. He is a researcher at University of Oldenburg, Germany. J Med Chem.

Clinical Trials 134

Clinical Trials Trials Small Molecule Disease 134

SCIENMAG: Medicine & Health

JULY 17, 2023

E-cigarette use more than doubled from 2017 to 2019 among middle and high school students. Statement Highlights: The number of people who use electronic nicotine delivery systems, typically referred to as e-cigarettes, has grown exponentially, especially among youth and young adults.

Research 67

Research 67

SCIENMAG: Medicine & Health

AUGUST 2, 2023

Researchers have found that robots can have a ‘U-shaped’ effect on profits: causing profit margins to fall at first, before eventually rising again.

Research 88

Research 88

keypoint

APRIL 16, 2024

These Next-Generation Grants aim to encourage and support early-career researchers who are applying disruptive concepts and inventive processes to advance human immunology, vaccine discovery, and immunotherapy research.

Vaccine 90

Vaccine International Research 90

Broad Institute

OCTOBER 4, 2023

Researchers from the Tumor Immunotherapy Discovery Engine ( TIDE ) at the Broad Institute of MIT and Harvard, AbbVie, and Calico Life Sciences report that the molecule simultaneously makes tumors more sensitive to immune attack and boosts the activity of immune cells to fight tumors in mice.

Small Molecule 128

Small Molecule Clinical Trials Trials Engineering 128

The Pharma Data

AUGUST 19, 2020

billion research centre in central London. The London Discovery Research Centre, as the site is to be named, has a tentative opening date of 2025 and will be based opposite King’s Cross station. MSD has lifted the lid on plans to build a $1.3

Research 52

Research Science 52

PPD

JUNE 20, 2024

Acceleration in every step of clinical research is critical to pharmaceutical developers. Yet, today’s clinical research sponsors face significant challenges. Rather than accepting the persistent delays in clinical research as disruptive, yet unavoidable, we believe they underscore the need for greater efficiency.

Clinical Research 52

Clinical Research Research Clinical Trials Pharmaceuticals 52

Drug Target Review

NOVEMBER 25, 2024

As the CEO of iOnctura, an innovative oncology biopharmaceutical company she co-founded in 2017, Catherine has played a key role in advancing the development of highly targeted small molecules aimed at revolutionising cancer treatment. I went on to complete my MBA and PhD at The Institute of Cancer Research (ICR) in drug development.

Treatment 52

Treatment Small Molecule Clinical Trials Trials 52

Drug Target Review

JULY 10, 2023

Despite decades of research and development, there are currently no drugs that can prevent or cure these diseases and only limited options for symptomatic relief. In summary, CNS research is a rapidly evolving field with a multitude of exciting developments and breakthroughs. 2017 Dec 11;9(1). 2017 Sep 1;49(9):1373–84.

Research 52

Research Disease Treatment Drug Development 52

FDA Law Blog: Biosimilars

MARCH 29, 2024

According to GAO, FDA is facing challenges with clinical research inspections to ensure that the sites that oversee the research that lead to drug approvals meet the necessary standards. These are BIMO inspections of hospitals, clinical research organizations (CROs), and other similar facilities where clinical trial work is performed.

Clinical Research 59

Clinical Research FDA Research Clinical Trials 59

Advarra

JUNE 12, 2023

Gene therapy research is exciting and full of promise, but because of the risks involved, it’s also highly regulated, requiring an institutional biosafety committee (IBC) to provide additional oversight and risk assessment. IRBs are tasked with protecting research subject’s rights and welfare. How are IBCs Different from IRBs?

Engineering 98

Engineering Therapies Regulations Research 98

Conversations in Drug Development Trends

AUGUST 10, 2023

With so many exciting developments in the last few years, it’s critical for the psychedelic community to come together to reflect on our progress, share the latest discoveries, and discuss the future of psychedelic research. Reflecting back on my conference experience, there are three key takeaways that stand out: 1.

Science 98

Science Clinical Trials Trials Clinical Research 98

Drug Target Review

JANUARY 25, 2024

Researchers from the Cleveland Clinic, led by Dr Ofer Reizes and Dr Justin Lathia, have developed a therapeutic peptide that disrupts the molecular processes behind aggressive cancer cell growth. 3 Therefore, the researchers aimed to disrupt this complex to limit the cancerous properties of the cells. Journal of Biomedical Science.

Treatment 105

Treatment Clinical Trials Science Research 105

NIOSH Science Blog: Drugs

AUGUST 2, 2023

A recently published research article explored patterns and characteristics of workers’ compensation injury claims over a 17-year period among firefighters in Ohio. Based on data from the OHBWC claims database, the researchers analyzed a comprehensive set of injury claims filed by firefighters from 2001-2017.

Research 68

Research 68

Broad Institute

OCTOBER 15, 2024

After completing his PhD in 2017, Brown joined Xavier’s lab as a postdoctoral researcher and has been at the Broad ever since, now as a staff scientist. We spoke with Brown about his experience as both a researcher and a patient in this #WhyIScience Q&A. What keeps you motivated to keep doing research?

Disease 125

Disease Immune Response Research Science 125

Drug Hunter

JUNE 5, 2023

Glecaprevir, or ABT-493, was approved in combination with pibrentasvir (Mavyret) for the treatment of Hepatitis C (HCV) in 2017. A Proprietary Catalyst in Roche’s Synthesis of Danoprevir Some pharmaceutical research teams have elected to develop and patent their own catalysts, with impressive results. Gonzalez-Bobes, F. Poongavanam, V.;

Process Chemistry 206

Process Chemistry Drugs Production Clinical Development 206

Alta Sciences

MARCH 4, 2025

Addressing New Challenges in Human Abuse Potential Research The CCALC has held face-to-face meetings in collaboration with industry, academia, and the FDA once every two to three years since inception, and has provided much of the industry perspective on the practical challenges and solutions to assessing abuse and dependence potential.

Clinical Trials 52

Clinical Trials FDA Drug Development Trials 52

Drug Target Review

APRIL 19, 2024

After ten years of exciting postdoctoral research around Europe in the astroparticle physics sector, hunting for dark matter at yet another offer from a foreign institution, I chose to create space for my life instead. Pure theoretical research is not in my chords, and I felt uncomfortable not being challenged by data. To participate.

Molecular Biology 111

Molecular Biology Research Pharmaceuticals Small Molecule 111

SCIENMAG: Medicine & Health

JULY 5, 2023

In 2017, the Nobel Prize in Medicine was bestowed upon researchers who made significant breakthroughs in […] This internal clock regulates vital physiological processes including sleep, metabolism, hormonal fluctuations, body temperature, and blood pressure.

International 59

International Regulations Research 59

The Pharma Data

JANUARY 13, 2021

13, 2021 — From 2010 to 2017, there were significant increases in the estimated rates of neonatal abstinence syndrome (NAS) and maternal opioid-related diagnoses (MOD), according to a study published in the Jan. In the national sample, there were 751,037 birth hospitalizations and 748,239 delivery hospitalizations in 2017.

Hospitals 52

Hospitals Research 52

Drug Target Review

AUGUST 16, 2023

Utilising just 15ul of patient serum samples, the researchers tested it with silver nanowires for various cancer types, capturing molecular vibrational changes indicative of altered physiology and pathology in cancer samples. References 1. Jillian Phallen. Direct detection of early-stage cancers using circulating tumor DNA.

DNA 98

DNA Disease Therapies Treatment 98

Broad Institute

APRIL 22, 2024

She is also a member of the steering committee for the Berkeley AI Research (BAIR) Lab. From 2007 to 2017 she was at Microsoft Research, through Cambridge, MA (2014-2017), Los Angeles (2008-2014), and Redmond, WA (2007-2008). She completed her Ph.D. Previous Jenn Nava Next Jesse Boehm

Molecular Biology 52

Molecular Biology Engineering Science Research 52

Drug Target Review

NOVEMBER 17, 2023

CAR-NK cell trials only commenced in 2017 and most are still recruiting patients. She obtained her PhD from the University of Wollongong in 2015 and gained extensive research experience as a postdoctoral fellow at Swinburne University of Technology, CSIRO, and Monash University, in the fields of immunology and tissue engineering.

Therapies 118

Therapies Clinical Trials Cell Biology Trials 118

The Pharma Data

SEPTEMBER 14, 2020

Call for Award Applicants: Johnson & Johnson Seeks Female Researchers Working in Science, Technology, Engineering, Math, Manufacturing and Design. Call for Award Applicants: Johnson & Johnson Seeks Female Researchers Working in Science, Technology, Engineering, Math, Manufacturing and Design.

Engineering 52

Engineering Science Research 52

The Pharma Data

NOVEMBER 2, 2020

adults by using blood pressure (BP) thresholds from the Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC7) and the 2017 American College of Cardiology-American Heart Association (ACC-AHA) BP guidelines. adults) using the 2017 ACC-AHA guideline criteria.

Pharmaceuticals 52

Pharmaceuticals Treatment Disease Research 52

Drug Target Review

SEPTEMBER 26, 2023

Human derived induced pluripotent stem cells (hiPSCs) have revolutionised research and are increasingly used for toxicology screening and disease modelling. 27,28 Since the advent of hiPSC technology almost two decades ago enormous progress has been made in many areas of research. 2017 Jan;155(1):234–47. 2017 Jul 6;21(1):14–7.

Drugs 111

Drugs FDA Disease Animal Testing 111

KIF1A

JUNE 17, 2023

Dylan Verden of KIF1A.ORG summarizes newly published KIF1A-related research and highlights progress in rare disease research and therapeutic development. The researchers assessed KIF1A’s speed, distribution, and ability to transport both small and large cargo across these 16 mutations. What’s a pre-print? .

Laboratories 98

Laboratories Therapies Disease Research 98

Codon

APRIL 17, 2025

In a 2017 study, the duo offered two possible explanations : Either Boquila had evolved a heightened ability to detect volatile chemicals emitted by nearby vegetation, or it was somehow borrowing genetic information from nearby microbes to camouflage itself. Here is a time-lapse video of a plant moving in response to changing sunlight.)

Research 60

Research DNA Engineering Government 60

keypoint

JANUARY 23, 2023

On March 24, 2023, Keystone Symposia will hosted a live ePanel event featuring the recipients of the Michelson Prizes: Next Generation Grants , an international prize that supports early-career researchers who are applying disruptive concepts and inventive processes to advance human immunology, vaccine discovery, and immunotherapy research.

Vaccine 52

Vaccine International Research 52

New Drug Approvals

NOVEMBER 13, 2023

Vodobatinib can be used for chronic myeloid leukemia (CML) research. Vodobatinib can be used for chronic myeloid leukemia (CML) research [1] [2]. VODOBATINIB 1388803-90-4 Molecular Weight 453.92 Vodobatinib exhibits activity against most BCR-ABL1 point mutants, and has no activity against BCR-ABL1T315I.

Treatment 63

Treatment Disease Therapies Production 63

Broad Institute

MARCH 8, 2024

On average, biomedical researchers do not receive their first major grant until the age of 43. Support The Next Generation Awards have strengthened Boston’s biomedical ecosystem by bolstering the careers of emerging scientists, helping them launch their own labs and develop as leaders in the research community.

Research 52

Research 52

Drug Target Review

DECEMBER 19, 2023

I don’t think it is a question of neuroscientists having to shoulder the responsibility of responding to and addressing questions of eco-anxiety, climate change, and environmental change, but rather a matter of upping the interest in this space and delivering more evidence through great research. I talked about methylmercury.

Science 115

Science Bioethics International Research 115

The Pharma Data

JANUARY 7, 2021

The pharmaceutical product landscape is rapidly and fundamentally changing with profound impact on research and development strategy and technology needs. The number of biopharmaceutical products show a considerable growth accounting for nearly a quarter of the new molecular entities approved in 2017.

Production 52

Production FDA Pharmaceuticals Marketing 52

The Pharma Data

OCTOBER 20, 2020

20, 2020 — In 2017 to 2019, 65.3 from the National Center for Health Statistics in Hyattsville, Maryland, used data from the 2017 to 2019 National Survey of Family Growth to provide information on current contraceptive status among women aged 15 to 49 years. The researchers found that 65.3 TUESDAY, Oct. and Joyce C.

Disease 52

Disease Research 52

The Pharma Data

JANUARY 17, 2021

Under the agreement, Daiichi Sankyo and ViGeneron will jointly conduct the first stage research and Daiichi Sankyo will have the option to negotiate a follow-on collaboration agreement for an undisclosed therapeutic target in the highly prevalent eye disease. MUNICH, Germany, Jan. Financial terms of the collaboration are not disclosed.

Therapies 40

Therapies Research Virus Disease 40

New Drug Approvals

MAY 8, 2025

Compounds useful as kinase inhibitors (WO 2017/103611 A1). “FDA Approval Summary: Pirtobrutinib for Relapsed or Refractory Mantle Cell Lymphoma” Clinical Cancer Research. 1] [2] [4] It inhibits B cell lymphocyte proliferation and survival by binding and inhibiting Bruton’s tyrosine kinase (BTK). [5] August 2023).

FDA Approval 52

FDA Approval FDA Therapies Trials 52

The Pharma Data

JANUARY 26, 2021

Department of Agriculture (USDA) recommendations for fruit and vegetable intake, respectively, in 2017, according to research published in the Jan. Data from the 2017 national and state Youth Risk Behavior Surveys were analyzed to calculate the percentage of students meeting intake recommendations. TUESDAY, Jan. Samantha J.

Disease 52

Disease Research 52