Broad Institute

OCTOBER 16, 2024

William Studier receives the 2024 Merkin Prize in ceremony at the Broad Institute for developing technology used to produce millions of doses of COVID-19 vaccines By Corie Lok October 16, 2024 Breadcrumb Home F. His T7 expression technology can be used to make large quantities of nearly any RNA or protein.

Vaccine

The Pharma Data

MARCH 1, 2022

Astellas”) today announced that they have entered into an agreement whereby Affinivax has reacquired the exclusive worldwide rights to ASP3772, a novel vaccine candidate targeting Streptococcus pneumoniae. We believe ASP3772 has significant potential to address unmet needs in this important vaccine category. Brugger, CEO of Affinivax.

Vaccine

The Pharma Data

MARCH 8, 2021

Valneva SE (“Valneva”), a specialty vaccine company focused on prevention of diseases with major unmet needs, and Pfizer Inc. It will compare the three-dose vaccination schedule (Month 0-2-6) with a two-dose schedule (Month 0-6). “We We are excited to be part of the Lyme disease vaccine development program with Valneva.

Vaccine

The Pharma Data

JULY 28, 2021

Safety profiles of Vaxzevria, and the mRNA-based vaccine were similar and overall favourable. Very rare clotting disorders (TTS) were observed with both vaccines but these were in line with what would be expected in the general population and lower than in those diagnosed with COVID-19.

Vaccine

The Pharma Data

DECEMBER 3, 2020

The Phase 1 trial was a randomized, observer-blind, placebo-controlled study to assess the safety, reactogenicity and immunogenicity of the adjuvanted COVID-19 S-Trimer vaccine candidates formulated with different antigen levels. No serious adverse events related to the vaccine candidates studied were reported.

Vaccine

The Pharma Data

JANUARY 31, 2021

Adjuvanted S-Trimer COVID-19 vaccine candidates demonstrated favorable safety and tolerability profiles and strong neutralizing immune responses in a phase 1 trial. Clover plans to initiate a global phase 2/3 trial in the first half of 2021 with an interim analysis for vaccine efficacy potentially in the middle of 2021.

Clinical Trials

The Pharma Data

JANUARY 31, 2021

Clover plans to initiate a global Phase 2/3 efficacy trial of its protein-based S-Trimer COVID-19 vaccine candidate adjuvanted with Dynavax’s CpG 1018 plus alum in the first half of 2021 with an interim analysis for vaccine efficacy potentially in the middle of 2021. EMERYVILLE, Calif. and CHENGDU, China , Feb.

Vaccine

The Pharma Data

DECEMBER 18, 2020

COVAX now has agreements in place to access nearly two billion doses of several promising vaccine candidates, and laid the groundwork for further doses to be secured through contributions from donors. billion donor-funded doses of approved vaccines in 2021 to the 92 low- and middle-income economies eligible for the COVAX AMC.

Vaccine

The Pharma Data

JULY 21, 2021

Valneva SE (Nasdaq: VALN; Euronext Paris: VLA), a specialty vaccine company focused on the development and commercialization of prophylactic vaccines for infectious diseases with significant unmet medical need, and Pfizer Inc. at Month 7). Juan Carlos Jaramillo M.D., About VLA15.

Vaccine

Drug Target Review

MARCH 15, 2024

He has a post-doctorate in virology, viral pathogenesis, viral vector development, and vaccines evaluation from Harvard Medical School, and a PhD in virology/molecular biology. 2017 Nov;33(6):1468-1475. Epub 2017 Sep 7. Cell Gene Therapy Insights 2017; 3(2), 131-158, 10.18609/cgti.2017.014. Biotechnol Prog.

Engineering

The Pharma Data

MARCH 24, 2021

New findings from a multi-country survey show that 50 per cent of parents whose child had a scheduled meningococcal disease (meningitis) vaccination appointment, had the appointment delayed or cancelled during the COVID-19 pandemic. pandemic’s impact on meningitis vaccinations over the last 12 months. About the Survey.

Vaccine

The Pharma Data

SEPTEMBER 30, 2021

As one among the leading global vaccines companies, we still bring options which help protect people’s health round the world,” said Michael Greenberg, MD, MPH, Medical Head, Sanofi Pasteur North America. “We 4,5 The CDC recommends a primary dose of the MenACWY vaccine at 11-12 years old and a second dose at 16 years old. In the U.S.,

Vaccine

The Pharma Data

JUNE 18, 2021

First approval of a conjugate vaccine that helps protect against 20 serotypes responsible for the majority of invasive pneumococcal disease and pneumonia, 1,2,3,4,5,6,7 including seven responsible for 40% of pneumococcal disease cases and deaths in the U.S. Senior Vice President and Head of Vaccine Research & Development, Pfizer.

Vaccine

Drug Target Review

OCTOBER 26, 2023

Alipogene tiparvovec and voretigene neparvovec-rzyl, two recombinant AAV-based gene therapy products, were approved by the European Medicines Agency (EMA) to treat lipoprotein lipase deficiency in 2012 2 and by the US Food and Drug Administration (FDA) to treat inherited retinal dystrophy in 2017, respectively. Wang D, Tai PW, Gao G.

Engineering

Codon

APRIL 9, 2024

Current vaccines and medicines work by intervening against these life phases. Credit: Tu Youyou Nobel Lecture As part of their effort to thoroughly document this project, Zhang, Li, and Rao published a 500-page oral history in 2015 and a monograph on the Project in 2017 that addressed sources in both Chinese and English.

Drugs

PLOS: DNA Science

JUNE 27, 2024

An article in Scientific Reports from 2017 points out that tardigrades could be the sole surviving species of a global environmental disaster. Another application of a tardigrade talent is the dry preservation of biomaterials, such as biologic drugs and vaccines.

DNA

Eye on FDA

FEBRUARY 8, 2024

The last time the agency issued less than 200 releases to the public was back in 2017. Finally, no surprise here, the number of announcements about new vaccine approvals fell as the COVID pandemic entered a new phase. This year the agency issued 190 releases, which is a substantial cutback from recent years in terms of sheer numbers.

FDA

Eye on FDA

JANUARY 12, 2022

And while the imprint of the communications style of a new commissioner is something that might be anticipated, we are getting a commissioner who we had once before in 2016-2017, a period where the quantity of communications was not robust. When will the products be fully approved?

FDA

LifeSciVC

JUNE 5, 2025

Anxiety in 2017 over NIH and FDA appointments preceded some of the strongest years of approvals, revenue, and funding. Investor Panel Pharma has money to spend The advent of COVID vaccines contributed to record global drug revenues, and the new obesity drugs appear to be following suit. This will not serve us or our patients well.

Science

Broad Institute

OCTOBER 4, 2023

Today, scientists use such reactions to produce the customizable DNA and RNA molecules that enable genetic sequencing, drug and vaccine development, pathogen tests, cancer diagnostics, and more. Caruthers recalled how, at a conference in 1975, he was openly questioned for working on the idea of synthesizing DNA.

DNA

The Pharma Data

MARCH 4, 2021

Under the 2017 collaboration agreement, Takeda received equity in Ovid and was eligible to receive up to $85 million in payments for regulatory milestones, including the initiation of Phase 3 clinical trials. We also make targeted R&D investments in Plasma-Derived Therapies and Vaccines.

Treatment

Drug Target Review

MARCH 21, 2024

Additionally, the COVID-19 RNA vaccines have already demonstrated how safe RNA can be, and we look forward to seeing additional safety data on RNA approaches as the field continues to grow. Of note, mRNA is redosable as opposed to AAV. AAV-based therapies often can’t be dosed more than once due to concerns about an immune response.

Therapies

Eye on FDA

JANUARY 26, 2023

Overall Fewer Press Releases – During 2022 the agency issued fewer press releases than in most previous years – 237 down from 285 the previous year and the fewest releases since 2017. There may be several factors at play. But the volume of COVID- related news has fallen off dramatically as has the agency’s activities.

FDA

The Pharma Data

MAY 13, 2021

Journal of the International Society of Sports Nutrition, 12(1), 43. [18] 18] Kumar, R., Saharia, K., Pradhan, D., & Subramaniam, J. Annals of neurosciences, 20(1), 13. [19] 19] Sharma, A. Basu, I., & Singh, S. The Journal of Alternative and Complementary Medicine. [20] 20] Chang CJ, Lin CS, Lu CC, et al.

Packaging

Alta Sciences

MAY 16, 2025

Recent developments in areas such as vaccines, Generally Recognized as Safe (GRAS) assessments, and related research have introduced complex challenges that may impact the pace of scientific progress. As toxicologists, we should be mindful of the future of our field.

Laboratories

The Pharma Data

APRIL 4, 2022

Dupixent was also granted Orphan Drug designation for the potential treatment of EoE in 2017. We provide potentially life-changing treatment options and life-saving vaccine protection to millions of people globally, while putting sustainability and social responsibility at the center of our ambitions. Source link: [link].

FDA

The Pharma Data

MARCH 15, 2022

Tobias was appointed CFO Designate of Haleon in December 2021, having been CFO of the division since 2017. Tobias Hestler. Prior to joining GSK, Tobias was the Chief Financial Officer at Sandoz – Novartis’ Generics Division. John has extensive healthcare, commercial and international experience.

International

Advarra

AUGUST 10, 2023

Gene therapy has achieved notable successes, particularly in treating resistant or refractory B cell leukemias (achieving overall response rates around 90% or greater) and the speed with which COVID-19 vaccines were developed under the original Operation Warp Speed. Why Warp Speed for Rare Diseases?

Drug Development

The Pharma Data

MARCH 9, 2022

Efanesoctocog alfa was granted Orphan Drug Designation by the US Food and Drug Administration (FDA) in August 2017 and the European Commission in June 2019. Submission in the EU will follow availability of data from the ongoing XTEND-Kids pediatric study, expected in 2023. The US FDA granted Fast Track Designation in February 2021.

Treatment

The Pharma Data

JUNE 1, 2022

The FDA granted efanesoctocog alfa Orphan Drug designation in August 2017 and Fast Track designation in February 2021. We provide potentially life-changing treatment options and life-saving vaccine protection to millions of people globally, while putting sustainability and social responsibility at the center of our ambitions.

Therapies

The Pharma Data

JANUARY 12, 2021

The roots of Bayer’s platform began in 2014, when the company stepped into the gene therapy space through a collaboration for hemophilia A with Dimension Therapeutics, which was later acquired by Ultragenyx in 2017. Although that never panned out as hoped, Bayer still saw significant potential in cell and gene therapy.

Therapies

The Pharma Data

NOVEMBER 1, 2021

DINC stands for “Docking INCrementally,” a protocol developed by Kavraki’s lab in 2013 to speed protein-peptide docking simulations that help researchers design drugs, vaccines and other processes involving large ligands.

Virus

The Pharma Data

MAY 15, 2021

Published 2017 Aug 1. doi:10.1515/hukin-2017-0069. Tufano JJ, Conlon JA, Nimphius S, et al. Effects of Cluster Sets and Rest-Redistribution on Mechanical Responses to Back Squats in Trained Men. J Hum Kinet. 2017;58:35?43. Hardee JP, Lawrence MM, Zwetsloot KA, Triplett NT, Utter AC, McBride JM. J Sports Sci. 2013;31(5):488?

Production

Elrig

MARCH 12, 2024

Steve was a founder member of the UK Government’s Vaccine Taskforce in the Covid crisis, sitting on its steering Board alongside Kate Bingham. He was made OBE for services to innovation in 2017 and became a Fellow of the Academy of Medical Science in 2020.

Research

Agency IQ

NOVEMBER 3, 2023

A 2017 European Parliament resolution called on the European Commission and the European Council “to formulate a better definition of the concept – and analyse the causes – of shortages of medicines.” Shortages increased by 60% between 2017 and 2019 in select European countries, the U.S.,

Regulations

Agency IQ

JULY 12, 2024

A 2017 European Parliament resolution called on the European Commission and the European Council “to formulate a better definition of the concept – and analyse the causes – of shortages of medicines.” Shortages increased by 60% between 2017 and 2019 in select European countries, the U.S.,

Regulations

The Pharma Data

NOVEMBER 10, 2020

Agency for Healthcare Research and Quality in Rockville, Maryland, used data from the 2014 to 2017 Medical Expenditure Panel Survey to estimate how many adults at increased risk for severe COVID-19 held essential jobs and could not work at home (WAH) or lived in households with essential workers. TUESDAY, Nov. 10, 2020 — Between 56.7

Vaccine