2020 - Drug Discovery Digest

First comprehensive look at effects of 2020-2021 California megafires on terrestrial wildlife habitat

Science Daily: Pharmacology News

NOVEMBER 21, 2023

In 2020 and 2021, California experienced fire activity unlike anything recorded in the modern record. When the smoke cleared, the amount of burned forest totaled ten times more than the annual average going back to the late 1800s. We know that wildlife in western forests evolved with changing habitat and disturbances like wildfire.

Scientific path to recouping the costs of climate change

Science Daily: Pharmacology News

APRIL 23, 2025

They report that carbon dioxide and methane output from just 111 companies cost the world economy $28 trillion from 1991 to 2020, with the five top-emitting firms linked to $9 trillion of those losses. The researchers use the tool to provide the first causal estimate of economic losses due to extreme heat driven by emissions.

Research

Climate change: Future of today's young people

Science Daily: Pharmacology News

MAY 7, 2025

C by 2100, 92% of children born in 2020 will experience unprecedented heatwave exposure over their lifetime, affecting 111 million children. If global temperatures rise by 3.5 Meeting the Paris Agreement's 1.5 C target could protect 49 million children from this risk.

Wellcome Photography Prize 2020 shortlist announced

Drug Discovery Today

JULY 27, 2020

44 shortlisted images from 13 countries; Categories are Social Perspectives, Hidden Worlds, Medicine in Focus, and two categories highlighting the 2020 theme of Mental Health;Winners to be announced digitally on 19 August

Genetic tracing at the Huanan Seafood market further supports COVID animal origins

Science Daily: Pharmacology News

SEPTEMBER 19, 2024

The data come from more than 800 samples collected in and around the Huanan Seafood Wholesale market beginning on January 1, 2020, and from viral genomes reported from early COVID-19 patients. The study is based on a new analysis of metatranscriptomic data released by the Chinese Center for Disease Control and Prevention (CDC).

Marketing

Marketing Virus Disease

Ships now spew less sulfur, but warming has sped up

Science Daily: Pharmacology News

AUGUST 12, 2024

New findings document fewer ship tracks, reduced cloud cover, and boosted warming after ship emissions regulations took effect in 2020.

Regulations

Video gaming improves mental well-being, landmark study finds

Science Daily: Pharmacology News

AUGUST 27, 2024

A pioneering study titled 'Causal effect of video gaming on mental well-being in Japan 2020-2022,' published in Nature Human Behaviour, has conducted the most comprehensive investigation to date on the causal relationship between video gaming and mental well-being.

Research

Hepatitis C Treatments: A Comprehensive Guide

Drugs.com

JULY 6, 2023

Centers for Disease Control and Prevention estimates that there were nearly 68,000 new cases of acute hepatitis C in 2020 and over 107,000 newly reported cases of chronic hepatitis C? THURSDAY, July 6, 2023 -- Did you know the U.S. To help you.

Treatment

Treatment Disease

This rocky planet around a white dwarf resembles Earth -- 8 billion years from now

Science Daily: Pharmacology News

SEPTEMBER 26, 2024

A 2020 microlensing event was caused by a planetary system with an Earth-like planet and brown dwarf. The star type was uncertain. The team has determined that the star is a white dwarf, a system resembling what our sun-Earth system will look like in 8 billion years.

Use of GLP-1 Meds Have Risen 7-Fold Among Young Americans

Drugs.com

MAY 22, 2024

WEDNESDAY, May 22, 2024 -- The number of American teens and young adults who've been prescribed one of the new GLP-1 weight-loss drugs soared nearly seven-fold between 2020 and 2023, a new report finds. That's compared to an overall decline of.

Drugs

Obese Kids May Face Higher Odds for Eczema, Psoriasis

Drugs.com

AUGUST 21, 2024

million Korean children between 2009 and 2020 revealed that children who became. WEDNESDAY, Aug. 21, 2024 -- Obese kids are more likely to develop immune-based skin problems like eczema or psoriasis, a new study says.Analysis of more than 2.1

A snapshot of relativistic motion: Special relativity made visible

Science Daily: Pharmacology News

MAY 5, 2025

In 1959, physicists James Terrell and Roger Penrose (Nobel laureate in 2020) independently concluded that fast-moving objects should appear rotated. However, this effect has never been demonstrated.

ADHD Diagnoses On The Rise Among Adults

Drugs.com

JANUARY 21, 2025

21, 2025 -- Attention-deficit/hyperactivity disorder (ADHD) diagnoses have increased among adults in recent years, while remaining stable among teenagers.ADHD diagnoses among adults increased by 15% between 2020 and 2023, after. TUESDAY, Jan.

Kids Still Find It Easy to Buy Flavored Vapes Online

Drugs.com

NOVEMBER 12, 2024

2020, the Preventing Online Sales of E-Cigarettes. TUESDAY, Nov. 12, 2024 -- If you think that federal restrictions on the sale of tobacco products make it nearly impossible for your teen to buy vapes online, new research suggests you're mistaken.In

Production

Production Research

Black Americans 20 Times More Prone to Gun Injuries Than Whites

Drugs.com

JULY 30, 2024

population in 2020, but suffered 61.5% TUESDAY, July 30, 2024 -- Black Americans, especially young Black men, face 20 times the odds of gun injury compared to whites, new data shows."Black Black persons made up only 12.6% of the U.S. of all firearm.

Watchdog Group Says U.S. Food Recalls Rose Again Last Year

Drugs.com

APRIL 25, 2024

recalls of foods for salmonella, foreign objects or undeclared allergens are rampant nowadays and the highest they've been since 2020, a watchdog group warns. THURSDAY, April 25, 2024 -- U.S. Everyone needs to do better: food producers,

Understanding the moon's history with Chang'e-5 sample

Science Daily: Pharmacology News

FEBRUARY 6, 2024

The sample landed with CE-5 in late 2020 and included a new mineral, Changesite-(Y), as well as a perplexing combination of silica minerals. China's Chang'e-5, the first lunar sample return mission since the Soviet Union's Luna 24 in 1976, delivered 1.73 kilograms of regolith from the Oceanus Procellarum, a plane named for its vast size.

Research

Steady Rise in U.S. Suicides Among Adolescents, Teens

Drugs.com

MARCH 29, 2024

rates of suicide by all methods rose steadily for adolescents between 1999 and 2020, a new analysis shows.During those two decades, over 47,000 Americans between the ages 10 and 19 lost their lives to suicide, the. FRIDAY, Match 29, 2024 -- U.S.

Young Workers' Injuries Rise After Recreational Marijuana Sales Made Legal

Drugs.com

FEBRUARY 23, 2024

Bureau of Labor statistics for 2006 through 2020 show that legal “recreational marijuana. FRIDAY, Feb. 23, 2024 -- After states legalize the sale of weed for recreational use, on-the-job injuries rise among younger workers, new research shows.U.S.

Research

FDA partially halts leukemia studies of Gilead cancer drug

BioPharma Drive: Drug Pricing

AUGUST 21, 2023

The hold is the latest setback for a drug that was the center of Gilead’s $5 billion acquisition of biotech Forty Seven in 2020.

FDA

FDA Drugs

More U.S. Kids, Teens Are Getting Weight-Loss Surgeries

Drugs.com

JUNE 7, 2023

Metabolic and bariatric surgeries among 10- to 19-year-olds rose by nearly 20% between 2020 and 2021, after climbing since. TUESDAY, June 6, 2023 -- As obesity rises among U.S. kids and teens, the number of weight-loss surgeries is growing, too.

PBMs and Drug Spending in 2020: Data from CVS Health (sort of), Express Scripts, Navitus, and WellDyne (rerun)

Drug Channels

DECEMBER 14, 2021

This year, we review 2020 data on commercial plan sponsor clients of CVS Health and Express Scripts along with two smaller PBMs—Navitus and WellDyne. Click here to see the original post and comments from July 2021. Since 2012, Drug Channels has examined commercial drug spending using the annual trend reports published by the largest PBMs.

Pharmacy

Pharmacy Drugs

Review of 505(b)(2) Drug Products Approved by USFDA from 2010 to 2020: A Focus on Intellectual Property and Regulatory Considerations

Drug Patent Watch

JULY 28, 2023

A review article in the Journal of Pharmaceutical Sciences analyzes the trends in drug repurposing through the 505(b)(2) pathway, as approved by the USFDA from 2010 to 2020.

Production

Production Science Drugs Pharmaceuticals

Biogen, Sage tremor drug fails key trial

BioPharma Drive: Drug Pricing

JULY 24, 2024

Known as SAGE-324, the drug was one of the key assets Biogen gained rights to through a billion-dollar research deal inked back in 2020.

Trials

Trials Drugs Research

Astronomers shed new light on formation of mysterious fast radio bursts

Science Daily: Pharmacology News

JULY 28, 2023

International team reports on a radio pulsar phase of a Galactic magnetar that emitted a fast radio burst in 2020; observations suggest unique origins for 'bursts' and 'pulses,' which adds to FRB formation theory.

International

With latest fundraise, Rome Therapeutics works to drug the ‘dark genome’

BioPharma Drive: Drug Pricing

SEPTEMBER 12, 2023

Johnson & Johnson and Bristol Myers Squibb have joined a group of new investors backing Rosana Kapeller’s startup, which launched in 2020 after incubating with GV.

Drugs

Wastewater pipe dig reveals 'fossil treasure trove'

Science Daily: Pharmacology News

AUGUST 28, 2023

Fossils of the world's oldest known flax snails, an extinct sawshark spine, and great white shark teeth have all been found in a mound of sand excavated from beneath Mangere Wastewater Treatment Plant in 2020.

Treatment

Treatment Research

Structure‐Based Design of 2‐Aminopyrazolpyrimidopyridone Derivatives as New Rearranged During Transfection (RET) Kinase Inhibitors

Chemical Biology and Drug Design

DECEMBER 30, 2024

In 2020, two selective RET inhibitors, selpercatinib and pralsetinib were approved by the US FDA. Therefore, 8w and 8s might be promising lead compounds. ABSTRACT RET (Rearranged during transfection) kinase is a validated target for non-small cell lung cancer (NSCLC). However, high treatment costs and clinically acquired resistance (e.g.,

FDA

FDA Therapies Treatment Research

Almost Half of Rural Americans Face Long Drives for Surgery

Drugs.com

FEBRUARY 12, 2025

By 2020, data show, 99 million Americans already had trouble. WEDNESDAY, Feb. 12, 2025 -- As closures of rural hospitals across the United States continue, more Americans are facing hour-plus drives to reach surgical centers, two new reports find.

Hospitals

Firearms Injuries Shot Up Following Pandemic, Study Says

Drugs.com

FEBRUARY 4, 2025

4, 2025 -- Hospitalizations for firearm injuries sharply increased in the wake of the COVID-19 pandemic after years of steady decline, a new study says.Overall, 34% more people landed in the hospital for a gunshot injury in 2020 and. TUESDAY, Feb.

Hospitals

Biotech IPOs bounced back in first quarter, but backlog remains

BioPharma Drive: Drug Pricing

APRIL 12, 2024

Proceeds from biotech IPOs during the first three months of 2024 matched levels seen in the first quarters of 2019 and 2020, BioPharma Dive data shows.

Retired Rugby Players Face Risks for Dementia, CTE

Drugs.com

JULY 18, 2024

By 2020, he had already been diagnosed with early onset dementia and. THURSDAY, July 18, 2024 -- Alix Popham played in two rugby World Cups and won a Six Nations Grand Slam before retiring in 2011 as a professional in the rough-and-tumble game.

Algernon Pharmaceuticals Gets Go-Ahead for Phase 3 COVID-19 Study | 2020-11-02

The Pharma Data

NOVEMBER 1, 2020

Vancouver-based Algernon Pharmaceuticals plans to conduct a late-stage study to evaluate an orally delivered drug, NP-120 (ifenprodil), as a COVID-19 treatment. The drug was originally developed in the 1990s by Sanofi to treat peripheral circulatory disorders and it is still used in generic form in Japan.

Pharmaceuticals

Pharmaceuticals Treatment Research Drugs

Spending on Kids' Mental Health Keeps Rising

Drugs.com

OCTOBER 4, 2023

children and adolescents has risen sharply since 2020. TUESDAY, Oct. 3, 2023 -- In yet another reminder of the psychic toll the pandemic has taken on young people, new research shows spending on mental health services for U.S. It climbed 26% for.

Research

Understanding the Regulatory Environment in Japan for Generic Drug Development

Drug Patent Watch

DECEMBER 30, 2024

Pharmaceutical Regulations in Japan 2020. Freyr Solutions. 11 Must-know FAQs about the Drug Approval Process in Japan. Retrieved from [link] Japan Pharmaceutical Manufacturers Association. Retrieved from [link] Pharmaceuticals and Medical Devices Agency. Regulatory System on Generic Drugs in Japan. Retrieved from [link] Raflzadeh-Kabe, J.

Drug Development

Drug Development Clinical Pharmacology Clinical Trials Pharmaceutical Companies

Exposure to neurotoxic rodenticide bromethalin in birds of prey

Science Daily: Pharmacology News

JULY 11, 2023

In 2020, Tufts Wildlife Clinic Director Maureen Murray, V03, published a study that showed 100% of red-tailed hawks tested at the clinic were positive for exposure to anticoagulant rodenticides (ARs). Such exposure occurs when these chemicals are used to kill mice or rats, which eat the poison, and the birds eat the poisoned prey.

Agios turns to Alnylam for help with rare disease push

BioPharma Drive: Drug Pricing

AUGUST 3, 2023

The biotech is acquiring rights to an RNA interference medicine Alnylam invented for a rare blood disorder, continuing a corporate makeover that began in 2020.

RNA

RNA Disease

David Liu receives Breakthrough Prize in Life Sciences

Broad Institute

APRIL 5, 2025

In 2016, 2020, and 2021, he was named one of the Top 20 Translational Researchers in the world by Nature Biotechnology, and was named one of Natures 10 researchers in the world.

Science

Science Clinical Trials DNA Disease

Cancer & COVID Drove Him to Double-Lung Transplant

Drugs.com

MAY 13, 2024

MONDAY, May 13, 2024 -- Chicago resident Arthur “Art” Gillespie fell ill in early March 2020 with COVID, after he and his father went to visit an uncle in a nursing facility.“I I was hospitalized for 12 days with a high fever and cough, and.

Nurses

Nurses Hospitals

Misrepresentation of Drugs in the Unregulated Market

Common Sense for Drug Policy Blog

NOVEMBER 15, 2024

2020 , van Amsterdam et al., When users consume illicit drugs of unknown content, quality, and dosage, their risk of overdose and other adverse health events increases significantly ( Singh et al., Even innocuous fillers can be harmful if administered in novel or unintended ways ( Cook et al., 2021 , Sehdev et al., 2022 , Green et al.,

Marketing

Marketing Drugs

The Codon Guide to Synthetic Biology

addgene Blog

SEPTEMBER 14, 2023

I spent about seven years working in research labs, and then pivoted to writing full-time in mid-2020. Many of them are software engineers, surprisingly, who have deep technical knowledge but little biology experience.)

Engineering

Engineering Research Molecular Biology

Nonacus introduces Whole Genome Sequencing service to support SARS-CoV-2 testing laboratories

Drug Discovery Today

MARCH 9, 2021

Assay development funded by Innovate UK grant for viral surveillance, received in May 2020 New service supports UK government test-to-release scheme for day 2 testing.

Laboratories

Laboratories Assay Development Government

Finding Hidden Treasure – how AI/ML can harness existing data to accelerate drug discovery

Drug Discovery Today

JUNE 10, 2020

For 2020 the BIO International Convention, usually one the world’s largest gatherings of the global biotech industry, is transitioning to a new, virtual event format.

International

International Drugs Science

ELRIG UK elects Melanie Leveridge to lead the organisation as Chair

Drug Discovery Today

SEPTEMBER 23, 2020

Drug discovery expert leads not-for-profit organisation to drive further collaboration between academia and biopharma industry; Melanie to chair ELRIG Drug Discovery Digital 2020 from 6–16 October

Drugs

First comprehensive look at effects of 2020-2021 California megafires on terrestrial wildlife habitat

Scientific path to recouping the costs of climate change

Trending Sources

Climate change: Future of today's young people

Wellcome Photography Prize 2020 shortlist announced

Genetic tracing at the Huanan Seafood market further supports COVID animal origins

Ships now spew less sulfur, but warming has sped up

Video gaming improves mental well-being, landmark study finds

Hepatitis C Treatments: A Comprehensive Guide

This rocky planet around a white dwarf resembles Earth -- 8 billion years from now

Use of GLP-1 Meds Have Risen 7-Fold Among Young Americans

Obese Kids May Face Higher Odds for Eczema, Psoriasis

A snapshot of relativistic motion: Special relativity made visible

ADHD Diagnoses On The Rise Among Adults

Kids Still Find It Easy to Buy Flavored Vapes Online

Black Americans 20 Times More Prone to Gun Injuries Than Whites

Watchdog Group Says U.S. Food Recalls Rose Again Last Year

Understanding the moon's history with Chang'e-5 sample

Steady Rise in U.S. Suicides Among Adolescents, Teens

Young Workers' Injuries Rise After Recreational Marijuana Sales Made Legal

FDA partially halts leukemia studies of Gilead cancer drug

More U.S. Kids, Teens Are Getting Weight-Loss Surgeries

PBMs and Drug Spending in 2020: Data from CVS Health (sort of), Express Scripts, Navitus, and WellDyne (rerun)

Review of 505(b)(2) Drug Products Approved by USFDA from 2010 to 2020: A Focus on Intellectual Property and Regulatory Considerations

Biogen, Sage tremor drug fails key trial

Astronomers shed new light on formation of mysterious fast radio bursts

With latest fundraise, Rome Therapeutics works to drug the ‘dark genome’

Wastewater pipe dig reveals 'fossil treasure trove'

Structure‐Based Design of 2‐Aminopyrazolpyrimidopyridone Derivatives as New Rearranged During Transfection (RET) Kinase Inhibitors

Almost Half of Rural Americans Face Long Drives for Surgery

Firearms Injuries Shot Up Following Pandemic, Study Says

Biotech IPOs bounced back in first quarter, but backlog remains

Retired Rugby Players Face Risks for Dementia, CTE

Algernon Pharmaceuticals Gets Go-Ahead for Phase 3 COVID-19 Study | 2020-11-02

Spending on Kids' Mental Health Keeps Rising

Understanding the Regulatory Environment in Japan for Generic Drug Development

Exposure to neurotoxic rodenticide bromethalin in birds of prey

Agios turns to Alnylam for help with rare disease push

David Liu receives Breakthrough Prize in Life Sciences

Cancer & COVID Drove Him to Double-Lung Transplant

Misrepresentation of Drugs in the Unregulated Market

The Codon Guide to Synthetic Biology

Nonacus introduces Whole Genome Sequencing service to support SARS-CoV-2 testing laboratories

Finding Hidden Treasure – how AI/ML can harness existing data to accelerate drug discovery

ELRIG UK elects Melanie Leveridge to lead the organisation as Chair

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