2025 and Treatment - Drug Discovery Digest

How AI will reshape pharma by 2025

Drug Target Review

DECEMBER 20, 2024

Looking ahead, 2025 could represent a major turning point for the pharmaceutical sector. These twins simulate how a patients condition might evolve without treatment, enabling researchers to compare the real-world effects of an experimental therapy against predicted outcomes.

Clinical Trials

Clinical Trials Trials Pharmaceuticals Drug Development

Rapid Blood Test Can Improve Stroke Treatment

Drugs.com

JANUARY 31, 2025

31, 2025 -- A rapid blood test could speed treatment for people whove suffered a stroke related to brain bleeding, a new study says.Stroke victims with brain bleeds have nearly seven times higher blood levels of a brain protein called. FRIDAY, Jan.

Treatment

Overactive Bladder Diagnoses Tripled, but Treatment Is Still Rare

Drugs.com

JANUARY 22, 2025

22, 2025 -- A sudden need to urinate is more common than previously known, but treatment is less common.Diagnoses for overactive bladder more than tripled between 2013 and 2017, after the American Urological Association (AUA). WEDNESDAY, Jan.

Treatment

FDA Approves Symbravo for Acute Treatment of Migraine in Adults

Drugs.com

FEBRUARY 5, 2025

5, 2025 -- The U.S. Food and Drug Administration has approved Symbravo (meloxicam and rizatriptan) for the acute treatment of migraine with or without aura in adults. WEDNESDAY, Feb. The approval was based on the results of three phase 3 trials of.

FDA Approval

FDA Approval Treatment FDA Trials

Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

From Research to Real-World Care 🌎 Understand how AI-driven advancements are shaping personalized treatments and patient outcomes. 📆 May 14th, 2025 at 9:30 AM PDT, 12:30 PM EDT, 5:30 PM BST Register today to save your seat!

Clinical Trials

FDA Approves Spravato Nasal Spray for Treatment-Resistant Depression

Drugs.com

JANUARY 22, 2025

22, 2025 -- The U.S. WEDNESDAY, Jan. Food and Drug Administration has approved Spravato (esketamine) CIII nasal spray for adults living with major depressive disorder who have had an inadequate response to at least two oral antidepressants.

FDA Approval

FDA Approval Treatment FDA Drugs

Should Your Teen Receive Non-Surgical Cosmetic Treatments?

Drugs.com

FEBRUARY 20, 2025

20, 2025 -- Social media often tempts teenagers with non-surgical ways to improve their appearance, such as laser hair removal, skin and teeth whitening, chemical peels, botox, and face and lip fillers.And a new poll finds that a. THURSDAY, Feb.

Treatment

Discovery of Elironrasib (RMC-6291), a Potent and Orally Bioavailable, RAS(ON) G12C-Selective, Covalent Tricomplex Inhibitor for the Treatment of Patients with RAS G12C-Addicted Cancers

Covalent Modifiers

FEBRUARY 25, 2025

Gill Journal of Medicinal Chemistry 2025 DOI: 10.1021/acs.jmedchem.4c02313 Seamon, Matthew Holderfield, Xing Wei, Yongxian Zhuang, Yu Chi Yang, Jingjing Jiang, Yue Huang, Ruiping Zhao, Yun Ling, Zhican Wang, Michael Flagella, Zhengping Wang, Mallika Singh, John E. Knox, Robert Nichols, David Wildes, Jacqueline A. Smith, Elena S.

Clinical Trials

Clinical Trials Treatment Trials

Cutting-Edge Cancer Treatment, CAR T-Cell Therapy, Isn't Known By Most Americans

Drugs.com

APRIL 21, 2025

MONDAY, April 21, 2025 -- Chris Vogelsang has had a long and terrible fight with cancer. Fourteen years ago, the 70-year-old man was first diagnosed with an aggressive form of lymphoma. His cancer has since returned twice, fighting against several.

Treatment

Treatment Therapies

Most People Worldwide Lack Good Treatment for Mental Illness

Drugs.com

FEBRUARY 11, 2025

11, 2025 -- About 93% of people worldwide who struggle with mental health or substance abuse issues aren't getting adequate care, a new report finds.In TUESDAY, Feb. many cases, people affected by mental illness do not recognize that they have a.

Treatment

Cutting-Edge Cancer Treatment Isn't Known By Most Americans

Drugs.com

APRIL 21, 2025

MONDAY, April 21, 2025 -- Chris Vogelsang has had a long and terrible fight with cancer.Fourteen years ago, the 70-year-old man was first diagnosed with an aggressive form of lymphoma.His cancer has since returned twice, fighting against several.

Treatment

Xenon gas could protect against Alzheimer's disease: Mouse study

Science Daily: Pharmacology News

JANUARY 15, 2025

Most treatments being pursued today to protect against Alzheimer's disease focus on amyloid plaques and tau tangles that accumulate in the brain, but new research points to a novel -- and noble -- approach: using Xenon gas. A phase 1 clinical trial of the treatment in healthy volunteers will begin in early 2025.

Disease

Disease Clinical Trials Treatment Trials

Biotech startup Airna raises $60M for RNA editing medicines

BioPharma Drive: Drug Pricing

JULY 31, 2024

Launched last September, the company is working on a treatment for alpha-1 antitrypsin deficiency, which it said could enter the clinic in 2025.

RNA

RNA Treatment

U.K. Kids Help Improve Treatment, Rehab For Traumatic Brain Injury

Drugs.com

FEBRUARY 20, 2025

20, 2025 -- Mia Jack was stealing a glance backward when she lost control of the quadbike shed been motoring around a family gathering.Jack, then 12, flew over the handlebars and slammed headfirst into a tree. THURSDAY, Feb. I was wearing a hel.

Treatment

FDA Approves Susvimo for Diabetic Macular Edema

Drugs.com

FEBRUARY 5, 2025

5, 2025 -- The U.S. Food and Drug Administration has approved Susvimo (ranibizumab) 100 mg/mL for treating diabetic macular edema.Susvimo is the first and only FDA-approved treatment shown to maintain vision in people with diabetic. WEDNESDAY, Feb.

FDA Approval

FDA Approval FDA Treatment Drugs

First Patient Cured of Sickle Cell Anemia

Drugs.com

MARCH 17, 2025

MONDAY, March 17, 2025 -- For 21 years, Sebastien Beauzile lived with the chronic pain of sickle cell anemia. Now, thanks to a groundbreaking genetic treatment, he is the first person in New York to be cured of the disease. Sickle cell was like.

Treatment

Treatment Disease

Injectable Drug, Xolair, Resolves Dangerous Food Allergies In One-Third Of Kids

Drugs.com

MARCH 3, 2025

MONDAY, March 3, 2025 -- More than a third of food-allergic kids were able to eat full servings of their trigger foods after treatment with an injectable asthma drug, new clinical trial findings report. In all, 36% of children treated with.

Clinical Trials

Clinical Trials Drugs Trials Treatment

Therapeutic Oligos 2025 Keynote Speakers Announced

Elrig

MARCH 25, 2025

I look forward to connecting with the ELRIG community later this year to discuss how we can further our understanding and treatment of human disease through insights and tools afforded by genomics. Back to Resources Find out more The post Therapeutic Oligos 2025 Keynote Speakers Announced appeared first on ELRIG.

RNA

RNA Bioinformatics Science Pharmacokinetics

Merck antibody reduces RSV-related disease, hospitalizations in trial

BioPharma Drive: Drug Pricing

OCTOBER 18, 2024

Detailed data from a Phase 2b/3 study of Merck’s treatment clesrovimab should support the company’s efforts to win approval by the 2025-2026 season.

Hospitals

Hospitals Disease Trials Treatment

FDA Approves Wearable Infusion Device for Advanced Parkinson Disease

Drugs.com

FEBRUARY 6, 2025

6, 2025 -- The U.S. Food and Drug Administration has approved Onapgo (apomorphine hydrochloride) injection as the first and only subcutaneous apomorphine infusion device for the treatment of motor fluctuations in patients with. THURSDAY, Feb.

FDA Approval

FDA Approval Disease FDA Treatment

Ready-Made Immune Therapy Effective Against Leukemia

Drugs.com

APRIL 28, 2025

MONDAY, April 28, 2025 -- A ready-made version of a cutting-edge cancer immunotherapy can effectively defeat blood cancers, a new study says.Researchers have prepared an off-the-shelf version of CAR immune cell treatment that can be administered.

Therapies

Therapies Treatment

FDA Approves Blujepa for Uncomplicated Urinary Tract Infections

Drugs.com

MARCH 25, 2025

TUESDAY, March 25, 2025 -- The U.S. Food and Drug Administration has approved Blujepa (gepotidacin) for the treatment of uncomplicated urinary tract infections (uUTIs) in adult women (weighing 40 kg or more) and children (12 years and older.

FDA Approval

FDA Approval FDA Treatment Drugs

FDA Approves TNKase for Acute Ischemic Stroke

Drugs.com

MARCH 6, 2025

THURSDAY, March 6, 2025 -- The U.S. Food and Drug Administration has approved TNKase (tenecteplase), a thrombolytic or clot-dissolving agent, for the treatment of acute ischemic stroke in adults.TNKase is delivered as a single five-second.

FDA Approval

FDA Approval FDA Treatment Drugs

Fitusiran

New Drug Approvals

APRIL 11, 2025

2] Fitusiran was approved for medical use in the United States in March 2025. [2] 2] The label also has a warning about liver toxicity and the need to monitor liver blood tests at baseline and then monthly for at least six months after initiating treatment with fitusiran or after a dose increase of fitusiran. [2] Fitusiran 1711.0g/mol,

Clinical Trials

Clinical Trials FDA FDA Approval Trials

FDA Approves Dupixent for Chronic Spontaneous Urticaria

Drugs.com

APRIL 23, 2025

WEDNESDAY, April 23, 2025 -- The U.S. Food and Drug Administration has approved Dupixent (dupilumab) for the treatment of adults and adolescents with chronic spontaneous urticaria.The approval is for patients 12 years and older who remain.

FDA Approval

FDA Approval FDA Treatment Drugs

Vaccine Shows Promise for Pancreatic Cancer, Study Finds

Drugs.com

FEBRUARY 21, 2025

21, 2025 -- Adding a personalized mRNA vaccine to standard treatment could offer new hope for pancreatic cancer patients, a small yet promising study from Memorial Sloan Kettering Cancer Center.The study followed 16 patients, including. FRIDAY, Feb.

Vaccine

Vaccine Treatment

“Chameleon” Immune Cells Linked To Severe Asthma

Drugs.com

JANUARY 22, 2025

22, 2025 -- A set of chameleon-like immune cells could be contributing to severe asthma in some patients.Intermediate group 2 innate lymphoid cells (ILC2s) appear to be able to get around cutting-edge asthma treatments by. WEDNESDAY, Jan.

Treatment

New Antibiotic May Be Effective in Treating Gonorrhea

Drugs.com

APRIL 15, 2025

TUESDAY, April 15, 2025 A newly approved antibiotic to treat urinary tract infections may also help fight drug-resistant gonorrhea, a new study shows.The medication, called gepotidacin, could become the first new gonorrhea treatment since the 1.

Treatment

Treatment Drugs

Sewer Sludge Is Dangerous to Health, EPA Says of Biosolids and PFAS

Drugs.com

JANUARY 17, 2025

17, 2025 -- Sewer sludge from wastewater treatment plants appears to expose farmers and nearby neighbors to toxic forever chemicals, a new U.S. FRIDAY, Jan. Environmental Protection Agency (EPA) draft risk assessment says.This sludge -- which is s.

Treatment

Orally Bioavailable and Site-Selective Covalent STING Inhibitor Derived from a Macrocyclic Marine Diterpenoid

Covalent Modifiers

MARCH 1, 2025

Zhang, and Lun Kelvin Tsou Journal of Medicinal Chemistry 2025 DOI: 10.1021/acs.jmedchem.4c02665 Moreover, orally administered GHN105 exhibited on-target engagement in vivo and markedly reversed key pathological features in a delayed treatment of the acute colitis mouse model.

Disease

Disease Treatment

Injectable Drug Resolves Dangerous Food Allergies In One-Third Of Kids

Drugs.com

MARCH 3, 2025

MONDAY, March 3, 2025 -- More than a third of food-allergic kids were able to eat full servings of their trigger foods after treatment with an injectable asthma drug, new clinical trial findings report.In all, 36% of children treated with.

Clinical Trials

Clinical Trials Drugs Trials Treatment

Count Me In launches new patient-partnered research project for translocation renal cell carcinoma

Broad Institute

MARCH 11, 2025

By Count Me In Communications March 11, 2025 Count Me In , a patient-partnered research initiative led by the Broad Institute of MIT and Harvard and Dana-Farber Cancer Institute, is launching a new project focused on translocation renal cell carcinoma (tRCC), a rare and aggressive form of kidney cancer.

Research

Research Medical Schools Treatment Disease

What Cancer Screenings Do You Need? A Quick Guide

Drugs.com

FEBRUARY 15, 2025

15, 2025 -- Cancer screenings can save lives by detecting cancer early, when treatment is most effective.With an estimated 2 million new cancer cases expected in 2025, regular screenings are more important than ever, according to the. SATURDAY, Feb.

Treatment

Researchers Find New Way to Curb Asthma Attacks

Drugs.com

MARCH 26, 2024

TUESDAY, March 26, 2025 -- A protein that shuts down immune cells in the lungs could be key to a new treatment for asthma attacks, a new report says.The naturally occurring protein, called Piezo1, prevents a type of immune cell called type 2 innate.

Research

Research Treatment

David Liu receives Breakthrough Prize in Life Sciences

Broad Institute

APRIL 5, 2025

David Liu receives Breakthrough Prize in Life Sciences By Corie Lok April 5, 2025 Breadcrumb Home David Liu receives Breakthrough Prize in Life Sciences Liu is honored for the development of base editing and prime editing, two gene editing technologies transforming medicine.

Science

Science Clinical Trials DNA Disease

Lung Cancer Remains At Bay Long After Immune Therapy Is Dropped

Drugs.com

APRIL 21, 2025

MONDAY, April 21, 2025 Immunotherapy might help keep lung cancer at bay for months or even years after the treatment has been abandoned due to side effects, a new study says.Immune checkpoint inhibitors essentially take the brakes off the immune s.

Therapies

Therapies Treatment

FDA Approves Combo of Opdivo Plus Yervoy for Advanced Liver Cancer

Drugs.com

APRIL 15, 2025

TUESDAY, April 15, 2025 -- The U.S. Food and Drug Administration has approved Opdivo (nivolumab) plus Yervoy (ipilimumab) as a first-line treatment for adults with unresectable or metastatic hepatocellular carcinoma (HCC).The The CheckMate-9DW.

FDA Approval

FDA Approval FDA Treatment Drugs

Déjà Vu: OPDP Again Targets Provider Branded Website of Accelerated Approval Drug in Second Untitled Letter of 2025

FDA Law Blog: Biosimilars

APRIL 13, 2025

By Sarah Wicks & Dara Katcher Levy FDAs Office of Prescription Drug Promotion (OPDP) issued its second Untitled Letter of 2025 to Taiho Oncology (Taiho) for a healthcare provider branded website for its drug LYTGOBI (futibatinib). Join us as we break down what went wrong this time. What Happened?

Drugs

Drugs FDA Trials Treatment

Q&A with Worldwide’s Rare Disease Experts: The Latest Innovations and Hopes for 2025

Conversations in Drug Development Trends

NOVEMBER 5, 2024

In preparation for World Orphan Drug Congress Europe, we interviewed Nathan Chadwick, Senior Director, Therapeutic Strategy Lead, Rare Disease, and Derek Ansel, MS, LCGC, Vice President, Therapeutic Strategy Lead, Rare Disease, to hear their insights into the current progress in rare disease research and their hopes for 2025.

Disease

Disease Clinical Trials Therapies Clinical Research

When is a Confirmatory Trial “Underway” or Conducted with “Due Diligence” Enough for Accelerated Approval? FDA Explains Its New Authorities

FDA Law Blog: Drug Discovery

JANUARY 30, 2025

To this end, the December 2024 draft guidance and a companion guidance published January 7, 2025, Accelerated Approval and Considerations for Determining Whether a Confirmatory Trial is Underway (the January 2025 draft guidance ) describe FDAs latest thinking on what it means to conduct a confirmatory trial with due diligence.

FDA

FDA Trials Disease Drugs

Stem Cell Therapy Repairs Irreversible Cornea Damage

Drugs.com

MARCH 5, 2025

WEDNESDAY, March 5, 2025 -- Sight-robbing injuries to the cornea can be repaired using a groundbreaking experimental stem cell treatment, a new study shows.The cornea -- the clear outermost layer of the eye -- can become irreversibly damaged if.

Therapies

Therapies Treatment

Ovarian Cancer Test May Miss Black and Native American Patients

Drugs.com

MARCH 21, 2025

FRIDAY, March 21, 2025 -- A blood test used to check for ovarian cancer may not work as well for Black and Native American women, a new study suggests.This could lead to delays in treatment and poorer health outcomes.The study, published in JAMA.

Treatment

FDA Expands Indication of Dust Mite Allergy Drug to Include Young Children

Drugs.com

MARCH 5, 2025

WEDNESDAY, March 5, 2025 -- The U.S. Food and Drug Administration has expanded its indication of Odactra, a house dust mite allergen tablet, for the treatment of house dust mite-induced allergic rhinitis, with or without conjunctivitis, to include.

FDA

FDA Drugs Treatment

Program Matches Breast Cancer Patients To Exercise, Rehab

Drugs.com

APRIL 28, 2025

MONDAY, April 28, 2025 -- Breast cancer patients fare better if they continue to exercise during their treatment, and a new program can help women get the activity they need to boost their odds, researchers say.The Comprehensive Oncology.

Treatment

Treatment Research

How AI will reshape pharma by 2025

Rapid Blood Test Can Improve Stroke Treatment

Trending Sources

Overactive Bladder Diagnoses Tripled, but Treatment Is Still Rare

FDA Approves Symbravo for Acute Treatment of Migraine in Adults

Bridging Innovation & Patient Care: The Growing Role of AI

FDA Approves Spravato Nasal Spray for Treatment-Resistant Depression

Should Your Teen Receive Non-Surgical Cosmetic Treatments?

Discovery of Elironrasib (RMC-6291), a Potent and Orally Bioavailable, RAS(ON) G12C-Selective, Covalent Tricomplex Inhibitor for the Treatment of Patients with RAS G12C-Addicted Cancers

Cutting-Edge Cancer Treatment, CAR T-Cell Therapy, Isn't Known By Most Americans

Most People Worldwide Lack Good Treatment for Mental Illness

Cutting-Edge Cancer Treatment Isn't Known By Most Americans

Xenon gas could protect against Alzheimer's disease: Mouse study

Biotech startup Airna raises $60M for RNA editing medicines

U.K. Kids Help Improve Treatment, Rehab For Traumatic Brain Injury

FDA Approves Susvimo for Diabetic Macular Edema

First Patient Cured of Sickle Cell Anemia

Injectable Drug, Xolair, Resolves Dangerous Food Allergies In One-Third Of Kids

Therapeutic Oligos 2025 Keynote Speakers Announced

Merck antibody reduces RSV-related disease, hospitalizations in trial

FDA Approves Wearable Infusion Device for Advanced Parkinson Disease

Ready-Made Immune Therapy Effective Against Leukemia

FDA Approves Blujepa for Uncomplicated Urinary Tract Infections

FDA Approves TNKase for Acute Ischemic Stroke

Fitusiran

FDA Approves Dupixent for Chronic Spontaneous Urticaria

Vaccine Shows Promise for Pancreatic Cancer, Study Finds

“Chameleon” Immune Cells Linked To Severe Asthma

New Antibiotic May Be Effective in Treating Gonorrhea

Sewer Sludge Is Dangerous to Health, EPA Says of Biosolids and PFAS

Orally Bioavailable and Site-Selective Covalent STING Inhibitor Derived from a Macrocyclic Marine Diterpenoid

Injectable Drug Resolves Dangerous Food Allergies In One-Third Of Kids

Count Me In launches new patient-partnered research project for translocation renal cell carcinoma

What Cancer Screenings Do You Need? A Quick Guide

Researchers Find New Way to Curb Asthma Attacks

David Liu receives Breakthrough Prize in Life Sciences

Lung Cancer Remains At Bay Long After Immune Therapy Is Dropped

FDA Approves Combo of Opdivo Plus Yervoy for Advanced Liver Cancer

Déjà Vu: OPDP Again Targets Provider Branded Website of Accelerated Approval Drug in Second Untitled Letter of 2025

Q&A with Worldwide’s Rare Disease Experts: The Latest Innovations and Hopes for 2025

When is a Confirmatory Trial “Underway” or Conducted with “Due Diligence” Enough for Accelerated Approval? FDA Explains Its New Authorities

Stem Cell Therapy Repairs Irreversible Cornea Damage

Ovarian Cancer Test May Miss Black and Native American Patients

FDA Expands Indication of Dust Mite Allergy Drug to Include Young Children

Program Matches Breast Cancer Patients To Exercise, Rehab

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