Drugs.com

MAY 27, 2025

TUESDAY, May 27, 2025 -- The U.S. percent for the treatment of plaque psoriasis of the scalp and body in adult and pediatric patients 12 years of age and older.Through. Food and Drug Administration has approved Zoryve (roflumilast) topical foam 0.3

FDA Approval 147

FDA Approval FDA Treatment Drugs 147

Covalent Modifiers

FEBRUARY 25, 2025

Gill Journal of Medicinal Chemistry 2025 DOI: 10.1021/acs.jmedchem.4c02313 Seamon, Matthew Holderfield, Xing Wei, Yongxian Zhuang, Yu Chi Yang, Jingjing Jiang, Yue Huang, Ruiping Zhao, Yun Ling, Zhican Wang, Michael Flagella, Zhengping Wang, Mallika Singh, John E. Knox, Robert Nichols, David Wildes, Jacqueline A. Smith, Elena S.

Clinical Trials 147

Clinical Trials Treatment Trials 147

Drugs.com

APRIL 21, 2025

MONDAY, April 21, 2025 -- Chris Vogelsang has had a long and terrible fight with cancer. Fourteen years ago, the 70-year-old man was first diagnosed with an aggressive form of lymphoma. His cancer has since returned twice, fighting against several.

Therapies 249

Therapies Treatment 249

Drugs.com

APRIL 21, 2025

MONDAY, April 21, 2025 -- Chris Vogelsang has had a long and terrible fight with cancer.Fourteen years ago, the 70-year-old man was first diagnosed with an aggressive form of lymphoma.His cancer has since returned twice, fighting against several.

Treatment 217

Treatment 217

Drugs.com

FEBRUARY 11, 2025

11, 2025 -- About 93% of people worldwide who struggle with mental health or substance abuse issues aren't getting adequate care, a new report finds.In TUESDAY, Feb. many cases, people affected by mental illness do not recognize that they have a.

Treatment 212

Treatment 212

BioPharma Drive: Drug Pricing

JULY 31, 2024

Launched last September, the company is working on a treatment for alpha-1 antitrypsin deficiency, which it said could enter the clinic in 2025.

RNA 293

RNA Treatment 293

Science Daily: Pharmacology News

JANUARY 15, 2025

Most treatments being pursued today to protect against Alzheimer's disease focus on amyloid plaques and tau tangles that accumulate in the brain, but new research points to a novel -- and noble -- approach: using Xenon gas. A phase 1 clinical trial of the treatment in healthy volunteers will begin in early 2025.

Disease 293

Disease Clinical Trials Treatment Trials 293

Drugs.com

MARCH 17, 2025

MONDAY, March 17, 2025 -- For 21 years, Sebastien Beauzile lived with the chronic pain of sickle cell anemia. Now, thanks to a groundbreaking genetic treatment, he is the first person in New York to be cured of the disease. Sickle cell was like.

Treatment 290

Treatment Disease 290

Drugs.com

FEBRUARY 5, 2025

5, 2025 -- The U.S. Food and Drug Administration has approved Susvimo (ranibizumab) 100 mg/mL for treating diabetic macular edema.Susvimo is the first and only FDA-approved treatment shown to maintain vision in people with diabetic. WEDNESDAY, Feb.

FDA Approval 287

FDA Approval FDA Treatment Drugs 287

Elrig

MARCH 25, 2025

I look forward to connecting with the ELRIG community later this year to discuss how we can further our understanding and treatment of human disease through insights and tools afforded by genomics. Back to Resources Find out more The post Therapeutic Oligos 2025 Keynote Speakers Announced appeared first on ELRIG.

RNA 59

RNA Bioinformatics Science Pharmacokinetics 59

Drugs.com

MARCH 3, 2025

MONDAY, March 3, 2025 -- More than a third of food-allergic kids were able to eat full servings of their trigger foods after treatment with an injectable asthma drug, new clinical trial findings report. In all, 36% of children treated with.

Clinical Trials 284

Clinical Trials Drugs Trials Treatment 284

BioPharma Drive: Drug Pricing

OCTOBER 18, 2024

Detailed data from a Phase 2b/3 study of Merck’s treatment clesrovimab should support the company’s efforts to win approval by the 2025-2026 season.

Hospitals 274

Hospitals Disease Trials Treatment 274

Drugs.com

FEBRUARY 20, 2025

20, 2025 -- Mia Jack was stealing a glance backward when she lost control of the quadbike shed been motoring around a family gathering.Jack, then 12, flew over the handlebars and slammed headfirst into a tree. THURSDAY, Feb. I was wearing a hel.

Treatment 200

Treatment 200

Drugs.com

JUNE 5, 2025

THURSDAY, June 5, 2025 — More American teenagers now use the weight-loss drug Wegovy, as doctors and families grow more comfortable with the treatment. But experts say access is still limited, and more research on its long-term safety in.

Doctors 174

Doctors Treatment Research Drugs 174

Drugs.com

FEBRUARY 6, 2025

6, 2025 -- The U.S. Food and Drug Administration has approved Onapgo (apomorphine hydrochloride) injection as the first and only subcutaneous apomorphine infusion device for the treatment of motor fluctuations in patients with. THURSDAY, Feb.

FDA Approval 269

FDA Approval Disease FDA Treatment 269

Covalent Modifiers

MAY 28, 2025

for compound 35 was found to be in the same range as for the two KRASG12Cinhibitors adagrasib and sotorasib, with clinically reported treatment-related adverse aminotransferase elevations leading to dose modifications. The calculated hepatotoxicity margin towards plasma exposure of 2.5

Drugs 130

Drugs Treatment Research Marketing 130

New Drug Approvals

APRIL 11, 2025

2] Fitusiran was approved for medical use in the United States in March 2025. [2] 2] The label also has a warning about liver toxicity and the need to monitor liver blood tests at baseline and then monthly for at least six months after initiating treatment with fitusiran or after a dose increase of fitusiran. [2] Fitusiran 1711.0g/mol,

Clinical Trials 107

Clinical Trials FDA FDA Approval Trials 107

Drugs.com

MARCH 25, 2025

TUESDAY, March 25, 2025 -- The U.S. Food and Drug Administration has approved Blujepa (gepotidacin) for the treatment of uncomplicated urinary tract infections (uUTIs) in adult women (weighing 40 kg or more) and children (12 years and older.

FDA Approval 262

FDA Approval FDA Treatment Drugs 262

Drugs.com

MARCH 6, 2025

THURSDAY, March 6, 2025 -- The U.S. Food and Drug Administration has approved TNKase (tenecteplase), a thrombolytic or clot-dissolving agent, for the treatment of acute ischemic stroke in adults.TNKase is delivered as a single five-second.

FDA Approval 261

FDA Approval FDA Treatment Drugs 261

Drugs.com

APRIL 23, 2025

WEDNESDAY, April 23, 2025 -- The U.S. Food and Drug Administration has approved Dupixent (dupilumab) for the treatment of adults and adolescents with chronic spontaneous urticaria.The approval is for patients 12 years and older who remain.

FDA Approval 245

FDA Approval FDA Treatment Drugs 245

Drugs.com

FEBRUARY 21, 2025

21, 2025 -- Adding a personalized mRNA vaccine to standard treatment could offer new hope for pancreatic cancer patients, a small yet promising study from Memorial Sloan Kettering Cancer Center.The study followed 16 patients, including. FRIDAY, Feb.

Vaccine 246

Vaccine Treatment 246

Drugs.com

JANUARY 22, 2025

22, 2025 -- A set of chameleon-like immune cells could be contributing to severe asthma in some patients.Intermediate group 2 innate lymphoid cells (ILC2s) appear to be able to get around cutting-edge asthma treatments by. WEDNESDAY, Jan.

Treatment 246

Treatment 246

Drugs.com

APRIL 15, 2025

TUESDAY, April 15, 2025 A newly approved antibiotic to treat urinary tract infections may also help fight drug-resistant gonorrhea, a new study shows.The medication, called gepotidacin, could become the first new gonorrhea treatment since the 1.

Treatment 245

Treatment Drugs 245

Drugs.com

JANUARY 17, 2025

17, 2025 -- Sewer sludge from wastewater treatment plants appears to expose farmers and nearby neighbors to toxic forever chemicals, a new U.S. FRIDAY, Jan. Environmental Protection Agency (EPA) draft risk assessment says.This sludge -- which is s.

Treatment 242

Treatment 242

Covalent Modifiers

MARCH 1, 2025

Zhang, and Lun Kelvin Tsou Journal of Medicinal Chemistry 2025 DOI: 10.1021/acs.jmedchem.4c02665 Moreover, orally administered GHN105 exhibited on-target engagement in vivo and markedly reversed key pathological features in a delayed treatment of the acute colitis mouse model.

Disease 130

Disease Treatment 130

Drugs.com

MARCH 3, 2025

MONDAY, March 3, 2025 -- More than a third of food-allergic kids were able to eat full servings of their trigger foods after treatment with an injectable asthma drug, new clinical trial findings report.In all, 36% of children treated with.

Clinical Trials 240

Clinical Trials Drugs Trials Treatment 240

Broad Institute

MARCH 11, 2025

By Count Me In Communications March 11, 2025 Count Me In , a patient-partnered research initiative led by the Broad Institute of MIT and Harvard and Dana-Farber Cancer Institute, is launching a new project focused on translocation renal cell carcinoma (tRCC), a rare and aggressive form of kidney cancer.

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Research Medical Schools Treatment Disease 113

Drugs.com

MARCH 26, 2024

TUESDAY, March 26, 2025 -- A protein that shuts down immune cells in the lungs could be key to a new treatment for asthma attacks, a new report says.The naturally occurring protein, called Piezo1, prevents a type of immune cell called type 2 innate.

Research 246

Research Treatment 246

Drugs.com

APRIL 28, 2025

MONDAY, April 28, 2025 -- A ready-made version of a cutting-edge cancer immunotherapy can effectively defeat blood cancers, a new study says.Researchers have prepared an off-the-shelf version of CAR immune cell treatment that can be administered.

Therapies 217

Therapies Treatment 217

Broad Institute

APRIL 5, 2025

David Liu receives Breakthrough Prize in Life Sciences By Corie Lok April 5, 2025 Breadcrumb Home David Liu receives Breakthrough Prize in Life Sciences Liu is honored for the development of base editing and prime editing, two gene editing technologies transforming medicine.

Science 144

Science Clinical Trials DNA Disease 144

Drugs.com

FEBRUARY 15, 2025

15, 2025 -- Cancer screenings can save lives by detecting cancer early, when treatment is most effective.With an estimated 2 million new cancer cases expected in 2025, regular screenings are more important than ever, according to the. SATURDAY, Feb.

Treatment 189

Treatment 189

Conversations in Drug Development Trends

APRIL 29, 2025

Unfortunately, this years event, scheduled for February 27-28, 2025, in Washington, DC, was abruptly postponed less than one week before it began. Thats why Worldwide Clinical Trials was committed to ensuring the rare disease community still had a space to share knowledge, resources, and support on Rare Disease Day 2025.

Disease 69

Disease Clinical Trials FDA Trials 69

FDA Law Blog: Biosimilars

APRIL 13, 2025

By Sarah Wicks & Dara Katcher Levy FDAs Office of Prescription Drug Promotion (OPDP) issued its second Untitled Letter of 2025 to Taiho Oncology (Taiho) for a healthcare provider branded website for its drug LYTGOBI (futibatinib). Join us as we break down what went wrong this time. What Happened?

Drugs 52

Drugs FDA Trials Treatment 52

Conversations in Drug Development Trends

NOVEMBER 5, 2024

In preparation for World Orphan Drug Congress Europe, we interviewed Nathan Chadwick, Senior Director, Therapeutic Strategy Lead, Rare Disease, and Derek Ansel, MS, LCGC, Vice President, Therapeutic Strategy Lead, Rare Disease, to hear their insights into the current progress in rare disease research and their hopes for 2025.

Disease 52

Disease Clinical Trials Therapies Clinical Research 52

Drugs.com

APRIL 15, 2025

TUESDAY, April 15, 2025 -- The U.S. Food and Drug Administration has approved Opdivo (nivolumab) plus Yervoy (ipilimumab) as a first-line treatment for adults with unresectable or metastatic hepatocellular carcinoma (HCC).The The CheckMate-9DW.

FDA Approval 190

FDA Approval FDA Treatment Drugs 190

Broad Institute

MAY 19, 2025

By Allessandra DiCorato May 19, 2025 Related content The Genetics of Eating Disorders study A new direct-to-participant effort now underway is giving people the opportunity to participate in the largest and most diverse genetic study of anorexia nervosa and other eating disorders to date.

DNA 88

DNA Medical Schools Treatment Hospitals 88

Drug Target Review

JUNE 5, 2025

Dr Aaron Haubner, Senior Manager of North America Medical Affairs and Market Access at Terumo Blood and Cell Technologies , reveals that while promising new treatments emerge, urgent partnerships are needed to ensure this essential blood therapy reaches the patients who need it most.

Disease 52

Disease Treatment Therapies Nurses 52