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Discovery and Optimization of a Covalent AKR1C3 Inhibitor

Covalent Modifiers

Our disclosure of a covalent inhibitor for potent AKR1C3 inactivation with proteome-wide selectivity in cells will expedite cell biological studies for testing the therapeutic potential of this metabolic target.

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Scientists reveal how energy is delivered into the cells major 'shipping port'

Science Daily: Pharmacology News

A team of scientists has answered a long-standing question in cell biology, uncovering how the cell's main energy currency, ATP, is transported into the endoplasmic reticulum (ER). Disrupted energy transport could affect diseases such as type 2 diabetes, cancer, and neurodegenerative disorders.

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Cell biology: How cellular powerhouses call for help when under stress

SCIENMAG: Medicine & Health

As life propagated across Earth in the form of the widest variety of single-celled organisms, sometime between 3.5 As a host cell, it offered […] and a billion years ago one such organism managed an evolutionary coup: Instead of devouring and digesting bacteria, it encapsulated its prey and used it as a source of energy.

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Miriam Merad, M.D., Ph.D., elected to the National Academy of Medicine for seminal work in immunology and cell biology

SCIENMAG: Medicine & Health

an esteemed immunologist at the Icahn School of Medicine at Mount Sinai, has been elected to the National Academy of Medicine (NAM) in recognition of her pioneering contributions to the fields of immunology and cell biology. Miriam Merad, M.D., Credit: Lab of Miriam Merad, MD, PhD Miriam Merad, M.D.,

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What is mCherry and How is it used?

biobide

These proteins have revolutionized cell biology with a variety of applications for monitoring cellular processes in vivo , protein tracking, or gene expression studies. mCherry is a fluorescent protein that presents a monomeric structure of 236 amino acids and a mass of 26.7

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SEB Centenary Conference 2023

SCIENMAG: Medicine & Health

This year’s SEB conference will feature over 800 talks covering the latest advances in experimental research across animal, plant and cell biology including impactful research in the fields of wildlife conservation, human disease and bio-inspired robotics, amongst many more.

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New machine learning-based single-cell search engine makes cell annotation faster, more efficient

Broad Institute

We wanted to build a tool like that for cell biology. So we took lots of reference single-cell RNA sequencing data from atlases and used our scalable machine learning algorithms to embed all of the gene expression data on these cells into compact vector representations — you can think of these as a signature for each cell.