Drug Target Review

JANUARY 12, 2024

How does the integration of Real-World Data (RWD) with genomic biomarker data contribute to a more comprehensive understanding of disease progression and treatment response? This one size fits all approach to drug prescribing still pervades in mostly all therapy areas except oncology. Most drugs do not work in all people.

Doctors 111

Doctors Clinical Trials Treatment Therapies 111

Broad Institute

OCTOBER 3, 2024

Largest-ever genetic study of epilepsy finds possible therapeutic targets By Ari Navetta October 3, 2024 Breadcrumb Home Largest-ever genetic study of epilepsy finds possible therapeutic targets Scientists have uncovered new genetic links to different types of epilepsy, which could lead to more tailored treatments.

DNA 133

DNA Doctors Treatment Disease 133

Drug Target Review

APRIL 14, 2025

With many healthcare systems prioritising cost-effectiveness, there is limited demand for novel treatments, even though they are crucial to combatting antibiotic resistance. Finrow highlights the economic challenges within the sector, particularly the reluctance of doctors to use new antibiotics when cheaper generic options are available.

Therapies 52

Therapies Marketing Drug Development Treatment 52

KIF1A

MAY 29, 2024

Fortunately, Sloane does not currently have epilepsy, and Megan hopes this treatment will prevent it’s onset as her disease progresses. On the day of the treatment, they checked into the hospital where Sloane was administered sedation medication. If all goes well, her treatments will continue on a quarterly basis thereafter.

Treatment 52

Treatment Doctors Hospitals Therapies 52

The Pharma Data

JUNE 12, 2025

The data show a significant and clinically meaningful improvement in patients’ hemoglobin levels after 24 weeks of treatment with Fabhalta, alongside additional health-related benefits. 2.29) after 24 weeks of treatment with Fabhalta. APPULSE-PNH demonstrated a mean improvement in Hemoglobin of 2.01 g/dL (95% CI, 1.74–2.29)

Therapies 40

Therapies Treatment Disease Doctors 40

Drug Target Review

OCTOBER 1, 2024

Since I was a child, I always wanted to be a doctor. From a human point of view, I have always considered doctors’ work as a sort of mission for the good of others. Being a doctor means giving courage and hope day in, day out to those experiencing illness. Oncology has come a long way in recent years.

Doctors 97

Doctors Therapies Science Pharma Companies 97

KIF1A

APRIL 25, 2024

She is scheduled to be the 2nd patient in the world to receive ASO therapy for KAND. Her mother, Megan, has offered to share their experience and journey with everyone to help us understand the process and to share in their hopes, fears, challenges, and successes that come along with ASO treatment. Hello KIF1A Community!

Therapies 52

Therapies FDA Approval FDA Treatment 52

FDA Law Blog: Biosimilars

DECEMBER 4, 2023

A prescription not issued in the usual course of professional treatment or in legitimate, authorized research is not a prescription within the meaning of the CSA and the pharmacist knowingly filling it, along with the prescriber issuing it, is subject to penalties. 21 U.S.C. § 829; 21 C.F.R. Complaint ¶ 58. Complaint ¶ 59. Complaint ¶ 62.

Pharmacy 139

Pharmacy Government Treatment Compliance 139

Olympian Clinical Research

NOVEMBER 9, 2022

Therefore, if you or a loved one is dealing with this rare condition, it’s essential to educate yourself about the condition and its potential treatments. Radiation therapy. To diagnose bullous pemphigoid, your doctor may order a blood test and take a skin biopsy. Bullous Pemphigoid Risk Factors and Causes.

Treatment 52

Treatment Clinical Research Immune Response Therapies 52

The Pharma Data

AUGUST 22, 2021

In the early days of the COVID-19 pandemic, doctors in Wuhan noticed something surprising. “There’s often a phenomenon that doctors report anecdotally, or that’s mentioned in passing in a particular research paper, and that provides a clue – a hook,” he said.

Doctors 52

Doctors Drugs Immune Response Virus 52

Antidote

FEBRUARY 22, 2024

Behind every new treatment is the incredible team of doctors, researchers, patients, and clinical trial specialists who worked on the research that made it possible.

Clinical Trials 69

Clinical Trials Trials Doctors Therapies 69

The Pharma Data

DECEMBER 9, 2020

9, 2020 — Side effects of radiation therapy in breast cancer patients are often missed by doctors, U.S. It was common for treatment side effects such as pain, itchy skin, swelling and fatigue to go unrecognized. WEDNESDAY, Dec. researchers report.

Therapies 52

Therapies Doctors Research Treatment 52

Drug Target Review

DECEMBER 4, 2023

Tailoring medical care to a patient’s unique genetic makeup, alongside the close analysis of disease progression, leads to more effective treatments, reduced side effects and faster diagnoses. What’s more, it remains an open question as to whether our healthcare facilities are currently equipped to deliver such treatment programmes at scale.

Treatment 105

Treatment Science DNA Doctors 105

PLOS: DNA Science

JUNE 1, 2023

The newest FDA-approved gene therapy treats the severe, skin-peeling condition dystrophic epidermolysis bullosa (DEB). The gene treatment has been a long time coming, but it differs from the handful of other approved gene therapies: it isn’t a one-and-done. DEB has been a candidate for a gene therapy since 2002.

FDA Approval 52

FDA Approval Therapies FDA Disease 52

Drug Target Review

OCTOBER 24, 2023

Live Bacterial Products (LBPs) will provide patients with a desirable, credible, safe and effective treatment option. The human microbiome, a complex ecosystem of microorganisms residing within our bodies, has emerged as a promising frontier in the quest for innovative medical treatments.

Treatment 122

Treatment Pharmaceuticals Pharmacokinetics Production 122

Drug Target Review

FEBRUARY 29, 2024

Through further research and work as a principal investigator on clinical studies for several central nervous system indications, I laid the groundwork for a career in gene therapy drug development. AskBio) I continue to work to bring innovative gene therapies to patients in need. In my current role at Asklepios BioPharmaceutical, Inc.

Therapies 111

Therapies Disease Clinical Trials Science 111

biobide

FEBRUARY 2, 2024

Pediatric cancers exhibit differences at the genetic level compared to the same form of adult disease, which may influence the selected treatment. Children and adolescents lack robust preclinical models to replicate the pathologies and provide precise and targeted therapies.

Disease 59

Disease Medical Schools Pharma Companies Clinical Trials 59

The Pharma Data

SEPTEMBER 23, 2020

I challenged my doctor quite often, always asking questions, ‘What’s next? When Lisa was diagnosed, CML was still in its early days of research, and the treatments that are currently available today were not available outside of some clinical trials 2. I had to rely on the doctor for all my answers.”. What can you do for me?

Doctors 52

Doctors Clinical Trials Treatment Disease 52

On Medicine

MARCH 22, 2023

A previous study involving brain tumor patients identified that when anti-tumor treatment is understood to be ‘the only option’, the risk and impact of side effects may not be adequately explained to and understood by patients. In some cases, photon RT can also cause abnormalities in hormone levels several years after treatment.

Therapies 52

Therapies Clinical Trials Trials Treatment 52

Drug Target Review

NOVEMBER 7, 2024

This targeted enhancement not only boosts the body’s natural mechanisms but also holds promise for developing novel treatments in immunology, where modulating immune responses can lead to more effective and durable therapeutic outcomes. In these conditions, the goal of therapy is typically to suppress or mitigate immune activity.

Disease 52

Disease Immune Response Regulations Engineering 52

Drug Target Review

SEPTEMBER 22, 2023

Organoid technologies are becoming an invaluable solution for preclinical research, with the ability to augment the development of personalised medicine, drug discovery and gene therapies. Organoids for cell therapy and drug discovery. Stem cell-derived organoids and their application for medical research and patient treatment.

Clinical Research 116

Clinical Research Research Drug Development Molecular Biology 116

The Pharma Data

DECEMBER 30, 2020

(NASDAQ: AXSM), a biopharmaceutical company developing novel therapies for the management of central nervous system (CNS) disorders, today announced positive results from the long-term, open-label Phase 3 MOVEMENT trial of AXS-07, Axsome’s novel, oral, multi-mechanistic investigational medicine in the acute treatment of migraine.

Trials 52

Trials Treatment Clinical Trials Therapies 52

H1 Blog

MAY 10, 2023

Healthcare providers are often the first line of defense in ensuring that people receive the medical treatment they need. From being key opinion leaders (KOLs) for pharma treatments to providing resources outside of going to see a doctor, it’s time to recognize the role that nurses can play in contributing to better health outcomes.

Nurses 52

Nurses Doctors Pharma Companies Clinical Trials 52

The Pharma Data

MAY 19, 2023

ABBOTT RECEIVES FDA APPROVAL FOR TACTIFLEX™ ABLATION CATHETER FOR TREATMENT OF ABNORMAL HEART RHYTHM Abbott (NYSE: ABT) today announced that the U.S. 6 “Abbott is leading the way in helping doctors manage common arrhythmias with the most holistic portfolio for this condition in the world,” said Christopher Piorkowski, M.D.,

FDA Approval 52

FDA Approval FDA Treatment Doctors 52

Broad Institute

JANUARY 25, 2024

“This could potentially help with disease prevention — if we know from someone’s retinal image that they are at high risk of developing glaucoma or cardiovascular disease in the future, we could refer them for follow-up screening or preventative treatment.”

Disease 124

Disease Research Science Medical Schools 124

KIF1A

AUGUST 20, 2024

So the pediatrician doctor requested the first cranial tomography, which also gave a normal result. Pauline is now 10 months old, undergoing physical and occupational therapy using the Cuevas method and is also having speech therapy sessions to help and strengthen the muscles involved in swallowing. You can help.

Doctors 52

Doctors Hospitals DNA Therapies 52

Drug Target Review

DECEMBER 13, 2023

These disease signatures capture both the linear and non-linear effects of genetic and molecular interaction networks and enable the identification of associations including those that are only relevant to a subgroup of patients that influence disease risk, prognosis and/or therapy response.

Bioinformatics 145

Bioinformatics Disease Regulations Immune Response 145

Alta Sciences

JUNE 27, 2023

Cancer Treatments, Clinical Trials, and the Motivation to Innovate nbartlett Tue, 06/27/2023 - 20:58 Getting to the Heart of Science with Michelle Newby At the heart of science are stories—stories of courage, challenges, successes, lessons, and people. Q: What was your cancer diagnosis and was treatment options were you given?

Clinical Trials 40

Clinical Trials Treatment Trials Science 40

Broad Institute

OCTOBER 23, 2024

They knew that discovering the genetic cause of her disorder would help them find other people like her, help get the condition formally recognized as a new disease, and help them better advocate for research into new treatments. It wasn’t until Emma that this possibility came on everyone’s radar,” said Carvill.

DNA 128

DNA RNA Disease Hospitals 128

Olympian Clinical Research

JANUARY 28, 2019

Just like with any other mental health-related disorder, the first step in treatment is identifying the problem. If you or someone you know is faced with the challenging effects of ADHD, it is important to take action and look for treatment options. But the reality is, it’s still a big struggle for many to cope with.

Clinical Research 61

Clinical Research Clinical Trials Treatment Doctors 61

KIF1A

JUNE 4, 2024

“We really hope that someday there will be a treatment that can help stop the progression of the symptoms, and give Elena and us more years to enjoy together.” Hundreds of doctor appointments and uncountable exams, second and third opinions, but nothing made sense. The day we received the KAND diagnosis the world stopped.

Doctors 52

Doctors Therapies Treatment Laboratories 52

The Pharma Data

JANUARY 17, 2021

They aren’t doctors, according to the American Association of Certified Orthoptists. But orthoptists are uniquely skilled in diagnosis and assist physicians in providing surgical and nonsurgical treatment for eye disorders, with an emphasis on binocular vision and eye movements. © 2021 HealthDay.

Medical Schools 52

Medical Schools Doctors Treatment Disease 52

Olympian Clinical Research

OCTOBER 14, 2021

The whole point of clinical trials is to gather information about new treatments and drugs. The more participants there are, the easier it will be for researchers and doctors to determine what works and what doesn’t work in real world conditions. You’ll Get Access to New, Cutting-Edge Treatments.

Clinical Trials 52

Clinical Trials Trials Doctors Therapies 52

Drug Target Review

FEBRUARY 26, 2024

Regarding therapy resistant melanomas, why is the alteration of the epigenetic landscape considered significant, and what has been lacking in terms of validated targetable epigenetic mechanisms? What is remarkable here is that we show that the addition of corin to BRAFi-resistant tumour cells resensitises them to BRAFi therapies.

Therapies 59

Therapies Molecular Biology Medical Schools Regulations 59

The Pharma Data

OCTOBER 29, 2020

29, 2020 — Long-term use of estrogen-only and combined estrogen and progestogen hormone replacement therapy (HRT) is associated with an increased risk for breast cancer, according to a study published online Oct. Study Updates Risks for Breast Cancer Associated With HRT. THURSDAY, Oct. 28 in The BMJ. Yana Vinogradova, Ph.D.,

Therapies 52

Therapies Doctors Treatment Research 52

Olympian Clinical Research

APRIL 18, 2023

Medical and surgical therapy may reduce the symptoms and keep them under control. To learn more about the causes and treatments for HS, Olympian Clinical Research ( OCR ) is hosting a research study on the condition. Hidradenitis suppurativa is a complex condition with limited treatment options.

Research 52

Research Clinical Research Doctors Treatment 52

Drug Target Review

SEPTEMBER 18, 2024

What specific cost-cutting measures can AI provide in the manufacturing process of cell and gene therapy, and how do these compare to traditional methods? The cell and gene therapy (CGT) space provides a great example of the potential of AI. AI can vastly improve cell culture, a critical step in cell therapy production.

Therapies 52

Therapies Doctors RNA Production 52