Fri.May 24, 2024

article thumbnail

This week in drug discovery (20-24 May) 

Drug Discovery World

News round-up for 20-24 May by DDW Senior Digital Content Editor Diana Spencer. The headline news this week emphasises the importance of shared expertise and collaboration, whether that be between nations, companies or research institutions, to enable the greatest advances in drug discovery. The top stories: Partners explore precision medicine approach to heart disease PlaqueTec and the Welch research group at the Babraham Institute have announced the completion of their collaboration to evaluat

Virus 130
article thumbnail

Ozempic Lowers Odds for Death, Illness in People With Kidney Disease and Type 2 Diabetes

Drugs.com

FRIDAY, May 24, 2024 -- Ozempic provides a wide variety of health benefits for people with kidney disease and type 2 diabetes, a major clinical trial has found. The drug significantly reduces the risk of severe kidney events, heart problems and.

Disease 124
Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Trending Sources

article thumbnail

Autoimmune mRNA therapeutics research collaboration 

Drug Discovery World

etherna has entered a research collaboration with Hasselt University (UHasselt) to develop an mRNA based treatment for autoimmune disorders. Funded by Flanders Innovation & Entrepreneurship (VLAIO), the project aims to combine etherna’s vast expertise in developing customised mRNA and lipid-based nanoparticle technologies for immuno-modulation with UHasselt’s research into autoimmune diseases with a particular focus on multiple sclerosis.

Research 130
article thumbnail

Louisiana Votes to Make Abortion Pills Controlled Substances

Drugs.com

FRIDAY, May 24, 2024 -- Louisiana has become the first state to pass a law that designates abortion pills as dangerous controlled substances. Once Gov. Jeff Landry signs the bill into law, as he is expected to do, possession of the drugs.

Drugs 122
article thumbnail

How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

article thumbnail

With Duchenne decision ahead, FDA’s Marks pushes for speedy gene therapy approvals

BioPharma Drive: Drug Pricing

But the head of the FDA’s CBER office didn’t tip where the agency stands on potentially broadening use of Sarepta’s Duchenne gene therapy Elevidys.

Therapies 119
article thumbnail

Charge your laptop in a minute or your EV in 10? Supercapacitors can help

Science Daily: Pharmacology News

Imagine if your dead laptop or phone could charge in a minute or if an electric car could be fully powered in 10 minutes. New research could lead to such advances.

Research 118

More Trending

article thumbnail

Imperceptible sensors made from 'electronic spider silk' can be printed directly on human skin

Science Daily: Pharmacology News

Researchers have developed a method to make adaptive and eco-friendly sensors that can be directly and imperceptibly printed onto a wide range of biological surfaces, whether that's a finger or a flower petal.

Research 112
article thumbnail

FDA Panel Gives Nod to Blood Test for Colon Cancer

Drugs.com

FRIDAY, May 24, 2024 -- A U.S. Food and Drug Administration advisory panel on Thursday recommended the approval of a new blood test that can spot colon cancer. The panel voted 7-2 that the benefits outweighed the risks when using the Guardant.

FDA 111
article thumbnail

Innovative material for sustainable building

Science Daily: Pharmacology News

Researchers introduce a polymer-based material with unique properties. This material allows sunlight to enter, maintains a more comfortable indoor climate without additional energy, and cleans itself like a lotus leaf. The new development could replace glass components in walls and roofs in the future.

Research 103
article thumbnail

New Steps Towards a Male Birth Control Pill

Drugs.com

FRIDAY, May 24, 2024 -- For decades, the responsibility for birth control has fallen largely on women, but new research suggests a birth control pill for men might one day become a reality. How does it work? It targets a protein required for.

Research 106
article thumbnail

Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

article thumbnail

Breakthrough discovery uses engineered surfaces to shed heat

Science Daily: Pharmacology News

Splash a few drops of water on a hot pan and if the pan is hot enough, the water will sizzle and the droplets of water seem to roll and float, hovering above the surface. The temperature at which this phenomenon, called the Leidenfrost effect, occurs is predictable, usually happening above 230 degrees Celsius. A team has now discovered a method to create the aquatic levitation at a much lower temperature.

article thumbnail

AI Might Help Spot Breast Cancer's Spread Without Biopsy

Drugs.com

FRIDAY, May 24, 2024 -- New AI can help detect breast cancer that is spreading to other parts of the body, without the need for biopsies, a new study finds. The AI analyzes MRI scans to detect the presence of cancer cells in the lymph nodes under.

105
105
article thumbnail

Entomologist sheds light on 250-year-old mystery of the German cockroach

Science Daily: Pharmacology News

Entomologists have solved the 250-year-old origin puzzle of the most prevalent indoor urban pest insect on the planet: the German cockroach. The team's research findings, representing the genomic analyses of over 280 specimens from 17 countries and six continents, show that this species evolved some 2,100 years ago from an outdoor-living species in Asia.

article thumbnail

Subtle Mental Declines Occur Before Older Folk Quit Driving

Drugs.com

FRIDAY, May 24, 2024 -- One of the toughest decisions seniors face is when to give up their keys and stop driving. Even slight changes to the ability to remember, think and reason can lead a senior to decide to stop driving, a new study.

105
105
article thumbnail

Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

article thumbnail

Caterpillars can detect their predators by the static electricity they emit

Science Daily: Pharmacology News

Caterpillars respond defensively to electric fields similar to those emitted by their natural predators, scientists have found.

105
105
article thumbnail

HPV Vaccine Is Also Preventing Cancers in Men: Study

Drugs.com

FRIDAY, May 24, 2024 -- Development and uptake of the human papilloma virus (HPV) vaccine has been crucial in reducing rates of virus-linked cervical cancers in women. Now, the accumulated data suggests the vaccine is saving men from fatal cancers.

Vaccine 103
article thumbnail

CDD Vault Update (May 2024 #3)

Collaborative Drug

Resume session A browser tab left inactive will automatically log out of CDD Vault according to the defined timeout period. Logging back in now returns to the exact page or search result instead of starting from a new search (landing page). This is also true when logging out either from the dedicated link or the timeout pop-up.

87
article thumbnail

Most Young Breast Cancer Survivors Can Have Children

Drugs.com

FRIDAY, May 24, 2024 -- Most young breast cancer survivors can go on to have children despite the effects of their lifesaving treatment, a new study shows. About 73% of breast cancer survivors attempting to conceive achieved a pregnancy and 65% had.

article thumbnail

Theory and experiment combine to shine a new light on proton spin

Science Daily: Pharmacology News

Nuclear physicists have long been working to reveal how the proton gets its spin. Now, a new method that combines experimental data with state-of-the-art calculations has revealed a more detailed picture of spin contributions from the very glue that holds protons together.

82
article thumbnail

In Experiments, Mice Got ill From Raw Milk Carrying Bird Flu Virus

Drugs.com

FRIDAY, May 24, 2024 -- Confirming the dangers of drinking raw cow's milk when the H5N1 avian flu virus is circulating in U.S. dairy herds, researchers found that mice fed the milk quickly got ill. "Our data indicate that HPAI A[H5N1] virus in.

Virus 96
article thumbnail

New patent expiration for Haleon Us drug CHILDREN’S ADVIL ALLERGY SINUS

Drug Patent Watch

Annual Drug Patent Expirations for CHILDREN%27S+ADVIL+ALLERGY+SINUS For more information on how DrugPatentWatch can help with your pharmaceutical business intelligence needs, contact admin@DrugPatentWatch.com or visit www.DrugPatentWatch.

Drugs 59
article thumbnail

Kickstarting the use of AI for biotechs: part two

Drug Target Review

In the last article, I noted select application areas where artificial intelligence (AI) & data can or are already being used: Generating and analysing existing data Designing compound structures Designing in vitro experiments Understanding and modelling biological mechanisms Extracting deep insights from across literature and study reports Designing proteins.

RNA 59
article thumbnail

New patent expiration for Haleon Us drug CHILDREN’S ADVIL-FLAVORED

Drug Patent Watch

Annual Drug Patent Expirations for CHILDREN%27S+ADVIL-FLAVORED For more information on how DrugPatentWatch can help with your pharmaceutical business intelligence needs, contact admin@DrugPatentWatch.com or visit www.DrugPatentWatch.

Drugs 59
article thumbnail

One of Canada’s Best Workplaces!

DrugBank

We are thrilled to share some fantastic news with our DrugBank community and beyond—thanks to our incredible team, DrugBank has been named one of the best places to work in Canada by the Great Place to Work® Institute!  This is the third year in a row we’ve landed a spot on the list, and the second year in a row we’ve ranked in the Top 5, landing in 5th place in the under 100 employees category this year.

52
article thumbnail

New patent expiration for Galderma Labs drug MIRVASO

Drug Patent Watch

Annual Drug Patent Expirations for MIRVASO Mirvaso is a drug marketed by Galderma Labs Lp and is included in one NDA. It is available from one supplier.

Drugs 59
article thumbnail

Create Custom Datasource for Dropdown Fields in Context-Aware Config Editor

Perficient: Drug Development

Sling Context-Aware Configuration in AEM ( Adobe Experience Manager ) provides the flexibility to set key value pairs for a business logic specific to a content path instead of site-wide configuration or template-wide configuration. For example, if you want to set different values for path /content/mysite/en and /content/mysite/es, then we can use the Context-Aware Configuration at the specific path level.

52
article thumbnail

A Guide to Creating and Developing a Clinical Data Management Plan

Quanticate

Crafting an effective Data Management Plan (DMP) is crucial for outlining the essential elements of study execution. Created at the outset, the DMP mandates thorough planning, significantly contributing to the study's efficiency and data integrity. Most organisations utilise a DMP template attached to a SOP, which includes generic content.

article thumbnail

Coffee Across Time Zones: Brewing Connections and Fostering Global Community at Perficient

Perficient: Drug Development

Building Genuine Connections in a Global Workplace In the ever-evolving landscape of the modern workplace, where collaboration often transcends geographical boundaries and time zones, the importance of fostering genuine human connection cannot be overstated. At Perficient, we recognize the value of cultivating a strong sense of community and belonging among our Global Community of colleagues, regardless of their location.

52
article thumbnail

New patent expiration for Abbvie drug LATISSE

Drug Patent Watch

Annual Drug Patent Expirations for LATISSE Latisse is a drug marketed by Abbvie and is included in one NDA. It is available from one supplier.

Drugs 59
article thumbnail

Will this Atara Biotherapeutics drug be the first approved therapy of its kind? 

Drug Discovery World

Atara Biotherapeutics has submitted a Biologics License Application (BLA) for Tabelecleucel (Tab-cel), a for treatment of Epstein-Barr virus positive post-transplant lymphoproliferative disease (EBV+ PTLD) with the US Food and Drug Administration (FDA). There are currently no FDA approved therapies in this treatment setting. It is indicated as monotherapy for treatment of adult and paediatric patients two years of age and older with EBV+ PTLD who have received at least one prior therapy.

Therapies 147
article thumbnail

New patent for Otsuka drug INQOVI

Drug Patent Watch

Annual Drug Patent Expirations for INQOVI Inqovi is a drug marketed by Otsuka and is included in one NDA. It is available from one supplier.

Drugs 59
article thumbnail

Optimize Multi-Modal AI: Part 2

Perficient: Drug Development

It was fantastic discussing solutions and opportunities around GenAI with many of you at Google NEXT last month. The landscape of business transformation has leveled up, and it’s incumbent upon all of us to be conscientious of the value of these amazing new products, while tempering our expectations of the outcomes as we explore these new solutions.

article thumbnail

Which pharmaceutical drugs have the most drug patents in Ireland?

Drug Patent Watch

This chart shows the drugs with the most patents in Ireland. Patents must be filed in each country (or, in some cases regional patent office) where patent protection is desired.

article thumbnail

Lilly to pour $5B more into expanding Zepbound, Mounjaro production

BioPharma Drive: Drug Pricing

The planned spending on new facilities in Lebanon, Indiana, brings its total commitment to the site to $9 billion, the largest single manufactuing investment in company history.