Wed.May 22, 2024

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SLAS Europe reveals New Product Award finalists

Drug Discovery World

SLAS has announced the finalists for its New Product Award, with the winners to be announced at the annual conference. The SLAS 2024 Europe Conference and Exhibition is heading back to Barcelona, 27-29 May, for its fifth annual European conference. It will feature scientific sessions and keynote presentations, discussion groups, new product demonstrations and extensive exhibition access time.

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Do Fish Oil Supplements Help or Harm the Heart?

Drugs.com

WEDNESDAY, May 22, 2024 -- Folks regularly taking fish oil supplements might not be helping their health as much as they might think, a new study suggests.Regular use of fish oil supplements could increase the risk of first-time heart disease and.

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Peptide shows promise as therapeutic for bone loss disorders

Drug Discovery World

Birmingham researchers have shown that a naturally occurring peptide holds promise as a new therapeutic for bone loss disorders and could have advantages over existing drugs. PEPITEM (Peptide Inhibitor of Trans-Endothelial Migration) was first identified in 2015 by University of Birmingham researchers. The latest research shows for the first time that PEPITEM could be used as a novel and early clinical intervention to reverse the impact of age-related musculoskeletal diseases.

Disease 147
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Cement recycling method could help solve one of the world's biggest climate challenges

Science Daily: Pharmacology News

Researchers have developed a method to produce very low emission concrete at scale -- an innovation that could be transformative in the transition to net zero. The method, which the researchers say is 'an absolute miracle', uses the electrically-powered arc furnaces used for steel recycling to simultaneously recycle cement, the carbon-hungry component of concrete.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Discover how organoids bridge the gap between the lab and clinic

Drug Discovery World

Developing new drugs is a complex and often lengthy process. A major roadblock lies in the limitations of traditional preclinical models, which often fail to accurately represent the intricate biology of human patients. Join DDW for a free event on 18 June, 3PM BST to learn more about how patient-derived organoids are revolutionising drug discovery.

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Use of GLP-1 Meds Have Risen 7-Fold Among Young Americans

Drugs.com

WEDNESDAY, May 22, 2024 -- The number of American teens and young adults who've been prescribed one of the new GLP-1 weight-loss drugs soared nearly seven-fold between 2020 and 2023, a new report finds. That's compared to an overall decline of.

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More Trending

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Too Few Asthma Patients Are Using Updated Inhalers

Drugs.com

WEDNESDAY, May 22, 2024 -- Improved inhalers are now available to help control asthma and treat sudden attacks, but a new study shows that hardly anyone’s using them.The new inhalers combine inflammation-fighting corticosteroids with a.

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Excavation reveals 'major' ancient migration to Timor Island

Science Daily: Pharmacology News

The discovery of thousands of stone artefacts and animal bones in a deep cave in Timor Island has led archaeologists to reassess the route that early humans took to reach Australia. Researchers dated and analysed the artefacts and sediment at the Laili rock shelter in central-north Timor-Leste, north of Australia, to pinpoint the arrival of the colonists.

Research 103
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More Americans Now Use Marijuana Each Day Than Alcohol

Drugs.com

WEDNESDAY, May 22, 2024 -- Reflecting changing times and legislation, Americans are now more apt to light up a joint or pop a weed gummy on a daily basis than they are to raise a glass of wine or beer, new research shows. Among folks who said they.

Research 111
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New patent for Ferring Pharms drug NOCDURNA

Drug Patent Watch

Annual Drug Patent Expirations for NOCDURNA Nocdurna is a drug marketed by Ferring Pharms Inc and is included in one NDA. It is available from one supplier.

Drugs 105
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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Pedestrians Twice as Likely to Be Hit by Electric Cars Versus Gas-Powered Ones

Drugs.com

WEDNESDAY, May 22, 2024 -- Many people have been caught by surprise when an electric-powered car has smoothly and silently crept up on them as they walked.But such an accident can pose a very serious risk to life and limb, and pedestrians might be.

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Using wobbling stellar material, astronomers measure the spin of a supermassive black hole for the first time

Science Daily: Pharmacology News

Astronomers have a new way to measure how fast a black hole spins, by using the wobbly aftermath from its stellar feasting. The results offer a new way to probe supermassive black holes and their evolution across the universe.

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Teen Cannabis Users' Risk for Psychosis May Be Stronger Than Thought: Study

Drugs.com

WEDNESDAY, May 22, 2024 -- Doctors have long known that excessive marijuana use can trigger psychosis, especially in the young. But new research suggests the link is stronger that ever imagined before.Teens who use cannabis face 11 times the odds.

Doctors 105
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The origin of the sun's magnetic field could lie close to its surface

Science Daily: Pharmacology News

Surprise findings suggest sunspots and solar flares could be generated by a magnetic field within the Sun's outermost layers. If confirmed, the findings could help scientists better predict space weather.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Health Savings Could Near $250,000 When Electric School Bus Replaces Diesel

Drugs.com

WEDNESDAY, May 22, 2024 -- It might be hoped that replacing a diesel school bus with a clean electric model would pay off for health and the environment.New research suggests that it does -- and gives a dollar figure for that payoff. Replacing a.

Research 105
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New AI accurately predicts fly behavior

Science Daily: Pharmacology News

Researchers trained an AI model to accurately predict male fruit flies' courtship behavior in response to any sight of a female. This breakthrough offers new insight into how the brain processes visual data and may someday pave the way for artificial vision technology.

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Scientists Discover Microplastics Abound in Human Testicles

Drugs.com

WEDNESDAY, May 22, 2024 -- In a finding that suggests microplastics may pose a special danger to men, a new study has shown that human testicles contain these tiny bits of plastic at levels triple that seen in animal testicles and human.

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Australian study proves 'humans are planet's most frightening predator'

Science Daily: Pharmacology News

A new study demonstrates that kangaroos, wallabies and other Australian marsupials fear humans far more than any other predator.

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CDC Warns Muslim Pilgrims to Saudi Arabia of Meningitis Outbreak

Drugs.com

WEDNESDAY, May 22, 2024 -- Muslim pilgrims attending the annual Hajj could be at risk for meningitis due to outbreaks occurring in Saudi Arabia, U.S. health officials warned this week.Twelve cases of meningitis linked to Umrah travel to Saudi.

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Milk from before antibiotic era were resistant to antibiotic tetracycline

Science Daily: Pharmacology News

The researchers started with 50 samples collected from 1941 to 1947, and they found that the samples contained seven different Streptococcus species, including two subspecies of S. dysgalactiae. Interestingly, the researchers found some of the samples were resistant to the antibiotic tetracycline and did not carry antibiotic resistance genes typically seen in today's antibiotic-resistant bacterial strains.

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'Climbing the Ladder' in Life Could Stave Off Dementia

Drugs.com

WEDNESDAY, May 22, 2024 -- Have you been socially and economically "upwardly mobile" through your life? If so, you may be doing your brain health a big favor, new Japanese research suggests.Folks who scored high in terms of "climbing the ladder".

Research 105
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Promethium bound: Rare earth element's secrets exposed

Science Daily: Pharmacology News

Scientists have uncovered the properties of a rare earth element that was first discovered 80 years ago at the very same laboratory, opening a new pathway for the exploration of elements critical in modern technology, from medicine to space travel.

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Only Half of Americans Feel Prepared to Save a Life in Emergencies: Poll

Drugs.com

WEDNESDAY, May 22, 2024 -- Only about half of Americans feel prepared to help someone during a medical emergency, a new poll finds.Only 51% of Americans think they would be able to perform hands-only CPR to help someone who’s collapsed.

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Boiling It Down: Conveying Complexity For Decision-makers

LifeSciVC

By Ankit Mahadevia, former CEO of Spero Therapeutics, as part of the From The Trenches feature of LifeSciVC Drug development is complex. So is running a business. Sometimes, the work of doing both can make your head spin. In my career as a CEO and Board Chair, I’ve found that one of the most important things a team can do is convey this complexity clearly and efficiently when it’s time to decide.

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Future climate impacts put whale diet at risk

Science Daily: Pharmacology News

A new study predicts future climate change impacts could disrupt the krill-heavy diet that humpback whales in the southern hemisphere consume.

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Biogen, looking to diversify, acquires immune drugmaker HI-Bio for $1.15B

BioPharma Drive: Drug Pricing

The deal, only Biogen’s third since the start of 2018, is a sign the company is open to branching out beyond the neurological drugs that have long been its focus.

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Under extreme impacts, metals get stronger when heated, study finds

Science Daily: Pharmacology News

Scientists have discovered that when metal is struck by an object moving at a super high velocity, the heat makes the metal stronger. The finding could lead to new approaches to designing materials for extreme environments, such as shields that protect spacecraft or equipment for high-speed manufacturing.

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The Potential of Cannabichromene (CBC) as a Therapeutic Agent [Minireview]

ASPET

There is a growing interest in the use of medicinal plants to treat a variety of diseases, and one of the most commonly used medicinal plants globally is Cannabis sativa. The two most abundant cannabinoids ( 9 -tetrahydrocannabinol and cannabidiol) have been governmentally approved to treat selected medical conditions; however, the plant produces over 100 cannabinoids, including cannabichromene (CBC).

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From Impossible to Inevitable: Transforming Undruggable Targets

DrugBank

In the dynamic world of drug discovery, the notion of "undruggable" targets presents both a significant challenge and an intriguing frontier for researchers and pharmaceutical companies. These tough nuts to crack in medical science—biological targets known to play roles in diseases but resistant to traditional drug design—are now seeing new strategies that shift the paradigm from "undruggable" to "druggable." The Challenge of Selectivity  Why are some t

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SixPeaks, a new obesity biotech, starts up with an option to sell to AstraZeneca

BioPharma Drive: Drug Pricing

AstraZeneca has an exclusive chance to buy the startup, which is developing a muscle-protecting weight loss medicine, within the next two years.

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New patent for Dexcel drug LANSOPRAZOLE

Drug Patent Watch

Annual Drug Patent Expirations for LANSOPRAZOLE Lansoprazole is a drug marketed by Ajanta Pharma Ltd, Alkem Labs Ltd, Breckenridge, Chartwell Molecular, Dr Reddys Labs Ltd, Glenmark Pharms Inc, Hetero Labs… Source

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Pfizer expands cost cuts with new $1.5B target

BioPharma Drive: Drug Pricing

The company, which previously announced plans to trim $4 billion in spending by the end of 2024, aims to save another $1.5 billion over the next three years.

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When Worlds Collide: The Theory of Real-World Evidence Meets Reality – Part II

FDA Law Blog: Biosimilars

By Jeffrey N. Gibbs & Ana Loloei & Véronique Li, Senior Medical Device Regulation Expert — We recently blogged about the Center for Devices and Radiological Health’s (CDRH) reluctance to make full use of real-world data (RWD) and real-world evidence (RWE) to support marketing applications. In response to the post, we did receive feedback from a company that had had the good fortune to have very positive experiences with RWD/RWE.

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Regeneron faces new biosimilar threats; An AI biotech lays off staff

BioPharma Drive: Drug Pricing

Today’s rundown also includes news of an expanded partnership for Boehringer Ingelheim and updates to emerging medicines from GSK and Bristol Myers.