Sat.Jan 11, 2025 - Fri.Jan 17, 2025

article thumbnail

‘The bar has risen’: China’s biotech gains push US companies to adapt

BioPharma Drive: Drug Pricing

Pharma dealmaking for drugs invented in China is putting pressure on U.S. biotechs to compete harder, according to investors and executives interviewed by BioPharma Dive at the J.P. Morgan Healthcare Conference.

Drugs 361
article thumbnail

DNA nanorobots can alter artificial cells

Science Daily: Pharmacology News

Scientists have succeeded in controlling the structure and function of biological membranes with the help of 'DNA origami'. The system they developed may facilitate the transportation of large therapeutic loads into cells. This opens up a new way for the targeted administration of medication and other therapeutic interventions. Thus, a very valuable instrument can be added to the toolbox of synthetic biology.

DNA 332
Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

article thumbnail

Evaluating GenMol as a Generalist Foundation Model for Molecular Generation

Nvidia Developer: Drug Discovery

Traditional computational drug discovery relies almost exclusively on highly task-specific computational models for hit identification and lead optimization. Traditional computational drug discovery relies almost exclusively on highly task-specific computational models for hit identification and lead optimization. Adapting these specialized models to new tasks requires substantial time, computational power, and expertisechallenges that grow when researchers simultaneously work across multiple ta

Drugs 126
article thumbnail

What Do Sleep Medications Do to Your Brain?

Drugs.com

MONDAY, Jan. 13, 2025 (HealthDay news) -- The sleep aid Ambien could be allowing toxic proteins to pollute the brain, potentially increasing a persons risk of disorders like Alzheimers disease.Drugs like the main ingredient in Ambien, zolpidem, sup.

290
290
article thumbnail

Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

article thumbnail

Roche’s new deals head tries to navigate a more ‘complicated’ and ‘expensive’ biotech world

BioPharma Drive: Drug Pricing

Roche's core research spans five large areas. Boris Zaïtra, who now leads corporate business development, is confident his team of dealmakers can juggle them.

Research 317

More Trending

article thumbnail

Leveraging AI Solutions for Clinical Trial Efficiencies

PPD

As clinical trials become increasingly complex, particularly in decentralized trials and rare disease studies, sponsors experience increased challenges in site selection, forecasting and resourcing, and patient recruitment and enrollment. Advanced artificial intelligence (AI) and machine learning solutions are revolutionizing critical challenge areas.

article thumbnail

Zolendrate (Reclast) Lowers Fracture Risk in Early Postmenopausal Women

Drugs.com

FRIDAY, Jan. 17, 2025 -- Women past menopause can protect themselves from future fractures through infrequent, cheap IV infusions of a bone-strengthening drug. Women 50 to 60 who got two IV infusions of zoledronate (Reclast) within five years had a.

Drugs 279
article thumbnail

JPM25: The FDA’s future, AbbVie’s second thoughts and Lilly’s lesson

BioPharma Drive: Drug Pricing

AbbVie's CEO hinted his company may be less willing to invest in psychiatry after a costly setback, while Lilly explained what it got wrong forecasting GLP-1 drug demand.

Drugs 316
article thumbnail

Critical ocean current has not declined in the last 60 years

Science Daily: Pharmacology News

The Atlantic Meridional Overturning Circulation (AMOC) has not slowed down since the mid-20th century based on the North Atlantic air-sea heat fluxes over that time. This finding contrasts with studies that have estimated a decline in the AMOC, likely because previous studies rely on sea surface temperature measurements to understand how the AMOC has changed.

358
358
article thumbnail

From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

article thumbnail

Scientific workflow for hypothesis testing in drug discovery: Part 2 of 3

Drug Target Review

Drug discovery scientists spend their days developing and testing complex hypotheses, leveraging data and expertise through workflows that utilise available tools. Operating a workflow, such as the one described in Figure 1, involves several key considerations that affect both the accuracy of results and the efficiency of the research process. Defining the research question A well-defined research question is the cornerstone of an effective scientific workflow in drug discovery.

Drugs 69
article thumbnail

Updated Guidelines for Preventing Osteoporosis-Related Fractures Released

Drugs.com

TUESDAY, Jan. 14, 2025 -- All women 65 and older should continue to be screened for osteoporosis, the nation’s leading preventive health panel says in an updated recommendation. The U.S. Preventive Services Task Force also recommends.

277
277
article thumbnail

Lilly blames slower-than-expected growth for 2024 sales miss

BioPharma Drive: Drug Pricing

The company said it overestimated demand of its obesity and diabetes drugs in the fourth quarter, but projected a further ramp-up in sales this year.

Drugs 312
article thumbnail

Engineering quantum entanglement at the nanoscale

Science Daily: Pharmacology News

Researchers have developed a drastically smaller and more energy efficient method of creating coveted photon pairs that influence each other from any distance. The technology could transform computing, telecommunications, and sensing.

article thumbnail

How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

article thumbnail

Why Google Patents Is Not a Good Solution to Identify Drug Patents

Drug Patent Watch

Identifying drug patents is crucial for various stakeholders, including researchers, legal professionals, and business strategists. While Google Patents is a widely used tool for searching patent information, it may not be the most effective solution for identifying drug patents. This article explores the limitations of Google Patents in this context and suggests alternative approaches.

Drugs 53
article thumbnail

CDC Confirms Another Human Bird Flu Case, Bringing Total to 67

Drugs.com

FRIDAY, Jan. 17, 2025 -- The U.S. Centers for Disease Control and Prevention (CDC) confirmed another human H5N1 avian flu case -- otherwise known as bird flu -- in California on Thursday, bringing the nationwide total of cases to 67.California has.

Disease 264
article thumbnail

5 questions facing emerging biotech in 2025

BioPharma Drive: Drug Pricing

Young drugmakers confront several harsh realities this year, among them a contracting sector and competition from China.

312
312
article thumbnail

Astrophysicists reveal structure of 74 exocomet belts orbiting nearby stars in landmark survey

Science Daily: Pharmacology News

Astrophysicists have imaged a large number of exocomet belts around nearby stars, and the tiny pebbles within them. The crystal-clear images show light being emitted from these millimeter-sized pebbles within the belts that orbit 74 nearby stars of a wide variety of ages -- from those that are just emerging from birth to those in more mature systems like our own Solar System.

338
338
article thumbnail

Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

article thumbnail

Mastering Database.SaveResult in Batch Class: A Beginner-Friendly Guide

Perficient: Drug Development

Imagine youre a skilled craftsman working in a massive warehouse. Every day, your task is to process thousands of unique items and ensure that each one is properly logged and stored. But lets face it mistakes happen. Sometimes an item gets mislabeled or damaged, and you need to know which ones to fix, and which ones made it safely through. In Salesforce, when working with a batch class that processes thousands or even millions of records, Database.SaveResult acts as your trusty supervisor, keep

article thumbnail

These Lifestyle Moves Help Ease Low Back Pain, Study Shows

Drugs.com

FRIDAY, Jan. 17, 2025 -- Suffering from low back pain?Addressing your unhealthy lifestyle habits could help ease your pain better than traditional care, a new study says.Back pain sufferers who got lifestyle coaching functioned better and had.

264
264
article thumbnail

Medicare will negotiate Novo’s GLP-1 drug price. Here’s what that means for Ozempic, Wegovy.

BioPharma Drive: Drug Pricing

Novo sells semaglutide as Ozempic and Rybelsus for diabetes and as Wegovy for obesity. In price talks, CMS will treat the different forms as a single product.

article thumbnail

United States dementia cases estimated to double by 2060

Science Daily: Pharmacology News

A new study shows that the risk of developing dementia anytime after age 55 among Americans is 42%, more than double the risk reported by older studies.

334
334
article thumbnail

Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

article thumbnail

Early Commercial Planning: Mitigate Patient Access Challenges for Cell and Gene Therapies

Fierce BioTech

Early Commercial Planning: Mitigate Patient Access Challenges for Cell and Gene Therapies swheeler Thu, 01/16/2025 - 17:26 Thu, 03/06/2025 - 11:00 Resource Type Webinar Fran Gregory, PharmD, MBA Josh Marsh Kathryne Kirk Kelly Kester Duration 60 minutes Cell and gene therapies (CGTs) offer fresh hope to patients with serious and debilitating diseases, often where no other treatment options are available.

article thumbnail

FDA Will No Longer Allow Use of Red Dye No. 3 in Food, Drugs

Drugs.com

WEDNESDAY, Jan. 15, 2025 -- The U.S Food and Drug Administration has amended its color additive regulations to no longer allow the use of Federal Food, Drug, and Cosmetic Act (FD&C Act) Red No. 3 in food and ingested drugs.FD&C Red No. 3 is.

FDA 264
article thumbnail

J&J to buy psychiatric drug developer Intra-Cellular for $14.6B

BioPharma Drive: Drug Pricing

Intra-Cellular has had success selling Caplyta, a brain-rebalancing drug that's approved to treat schizophrenia and bipolar depression.

article thumbnail

Is eating more red meat bad for your brain?

Science Daily: Pharmacology News

People who eat more red meat, especially processed red meat like bacon, sausage and bologna, are more likely to have a higher risk of cognitive decline and dementia when compared to those who eat very little red meat, according to a new study.

328
328
article thumbnail

Glycoproteomic biomarkers in the clinic: How InterVenn is powering the development of predictive biomarkers for therapeutic response.

Fierce BioTech

Glycoproteomic biomarkers in the clinic: How InterVenn is powering the development of predictive biomarkers for therapeutic response. pesurya Thu, 01/16/2025 - 14:23 Thu, 02/27/2025 - 14:00 Resource Type Webinar Dr. David Braun Dan Serie, M.S. Alex Vanotti, MBA Duration 60 Minutes The search for biomarkers for therapeutic response using traditional genomic sequencing and other omic approaches has not yielded clinically actionable tools for most patients.

article thumbnail

Diabetes Drug Protects Against Skin Cancer, New Research Says

Drugs.com

TUESDAY, Jan. 14, 2025 -- A popular diabetes drug can provide protection against skin cancers, a new study says.Metformin significantly reduces peoples risk of developing basal cell cancers or squamous cell cancers, the two most common skin c.

Research 264
article thumbnail

Tune raises $175M for hepatitis B medicine, epigenetic research

BioPharma Drive: Drug Pricing

The biotech plans to use the funding to advance clinical testing of an epigenetic silencing therapy it hopes could treat chronic hepatitis B infections.

Research 214
article thumbnail

Bird flu is mutating, but antivirals still work

Science Daily: Pharmacology News

Researchers have identified nine mutations in a bird flu strain from a person in Texas. Bad news: this strain is more capable of causing disease and replicates better in the brain. Good news: approved antivirals are still effective.

Disease 325