Drug Target Review

APRIL 14, 2025

The antibiotic market has long faced significant barriers to innovation, with structural issues that make it difficult for new antibiotics to gain traction. As the demand for novel antibiotics remains limited due to the preference for cheaper generics, the market has struggled to incentivise much-needed breakthroughs.

Therapies

LifeSciVC

JUNE 12, 2025

We built our proprietary OPERA platform ( here ), leveraging oligonucleotide guided RNA editing to modulate protein expression. As I wore my engineering hat, the most prudent way was to modify one variable at a time, and control known variables. The experiment worked and showed the precision of RNA editing.

RNA

Codon

APRIL 14, 2025

In the four years I’ve been working as a machine learning engineer at Dyno Therapeutics , a biotechnology company in Boston, I’ve become increasingly convinced that biologists have an almost masochistic tolerance for difficult and protracted work. Many CROs operate in small, captive markets with high switching costs.

Protein Expression

Drug Target Review

APRIL 5, 2024

Together, these attributes provide a strong foundation for protein expression with enough adaptability to produce much of the commercial and therapeutic protein market.

Protein Production

Codon

DECEMBER 10, 2023

A zoologist, ecologist, and protein engineer all call themselves “biologists,” but rarely attend the same conferences. Align to Innovate’s Open Datasets Initiative (one of us, Erika DeBenedictis, is the founder) roadmaps high-impact datasets in biology, and then hires automation engineers to collect them.

Protein Expression

Codon

DECEMBER 10, 2023

A zoologist, ecologist, and protein engineer all call themselves “biologists,” but rarely attend the same conferences. Align to Innovate’s Open Datasets Initiative (one of us, Erika DeBenedictis, is the founder) roadmaps high-impact datasets in biology, and then hires automation engineers to collect them.

Protein Expression

Drug Target Review

JULY 5, 2023

This selectable marker enables the identification of cells which have taken up the GOIs and aids the initial selection of recombinant protein expressing cell lines. A potential future for host cell lines There have been many recent advances in cell line engineering technologies and our understanding of CHO cells.

Engineering