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Advancements in hit identification for membrane protein drug discovery

Drug Target Review

The challenge of GPCR drug discovery G protein-coupled receptors (GPCRs) are one of the most desirable and challenging target classes in drug discovery, as their mutation can lead to a wide range of diseases such as cancer, cardiovascular disorders and neurological conditions.

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High Throughput Screening (HTS)

Sygnature Discovery

Employing a comprehensive strategy for hit identification, we use the most effective methods to accurately pinpoint hit series that have the highest potential for evolving into compounds with drug-like properties. These include quality robust assays, reliable automation, secure data, and the quality of the libraries.

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Advancing Precision Oncology: Leveraging multidimensional biomarker insights with CGIP for efficient drug development and enhanced patient outcomes

Fierce BioTech

Advancing Precision Oncology: Leveraging multidimensional biomarker insights with CGIP for efficient drug development and enhanced patient outcomes scox Wed, 04/16/2025 - 17:44 Thu, 05/29/2025 - 11:00 Resource Type Webinar Taylor Jensen, Ph.D. Precision oncology drug development faces increasing costs and complexity.

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RNA processing in health and disease: challenges and opportunities of the field

Drug Target Review

In this article Drug Target Review’s Izzy Wood spoke to Sam Hasson, Director of Target Biology at Rgenta Therapeutics, a biotech firm in Massachusetts, US, that aims to develop small molecule therapeutics to target RNA processing. Ribonucleic acid strands consisting of nucleotides important for protein bio-synthesis entering cell.

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9th RSC-BMCS Fragment-based Drug Discovery Meeting

Zobio

In person ZoBio attended the 9th RSC-BMCS Fragment-based Drug Discovery meeting in Cambridge. The meeting focused on case studies in Fragment-based Drug Discovery that have delivered compounds to late stage medicinal chemistry, preclinical or clinical programs.

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9th RSC-BMCS Fragment-based Drug Discovery Meeting

Zobio

In person ZoBio attended the 9th RSC-BMCS Fragment-based Drug Discovery meeting in Cambridge. The meeting focused on case studies in Fragment-based Drug Discovery that have delivered compounds to late stage medicinal chemistry, preclinical or clinical programs.

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Six Factors for Biotech Companies to Consider When Choosing Next-Generation Contract GMP/CMC Laboratories

PPD

With the depth of knowledge to support all types of pharmaceutical products across all phases of development, we provide services ranging from end-to-end assay development to platform expansion, designed with the client’s timeline and budget in mind. Stay ahead of the curve with a great GMP/CMC contract laboratory partner.