PLOS: DNA Science

JANUARY 25, 2024

DNA Science has described intriguing sources of environmental DNA, aka eDNA: DNA in Strange Places: Hippo Poop, Zoo Air, and Cave Dirt and A Glimpse of the Ocean’s Twilight Zone Through Environmental DNA. The post Chewing Gum Reveals Stone Age Diet and Disease appeared first on DNA Science.

Disease 97

Disease DNA Science Virus 97

Broad Institute

JANUARY 8, 2024

Williams January 8, 2024 Credit: Susanna Hamilton, Broad Communications Researchers have developed virus-like particles that can deliver gene-editing cargo to cells, including those in the mouse brain. Delivery dilemma Gene editing approaches promise to treat a range of diseases by precisely correcting genetic mutations that cause disease.

Engineering 144

Engineering Research Virus DNA 144

Broad Institute

MAY 16, 2024

The enormous challenge of getting therapies past this barrier — a highly selective membrane separating the blood from the brain — has stymied the development of safer and more effective gene therapies for brain diseases for decades.

Therapies 137

Therapies FDA Approval Engineering Disease 137

SCIENMAG: Medicine & Health

SEPTEMBER 7, 2023

Hand washing and disinfection are important hygiene practices to minimize the probability of catching infectious diseases. While this had been known to science […] Contact infection is among the most common ways pathogens, such as bacteria and viruses, spread from one person to another.

Virus 84

Virus Science Disease 84

The Pharma Data

JUNE 24, 2025

Biologic drugs, including monoclonal antibodies, have become essential in the treatment of a wide array of conditions, from autoimmune diseases to various cancers. To date, more than 160 monoclonal antibody therapies targeting nearly 100 disease-related proteins have received regulatory approval globally.

Therapies 40

Therapies Biosimilars Compliance Virus 40

The Pharma Data

MARCH 5, 2021

Gilead Sciences, Inc. The acquisition provides Gilead with Hepcludex ® (bulevirtide), which was conditionally approved by the European Medicines Agency for the treatment of chronic hepatitis delta virus (HDV) in adults with compensated liver disease in July 2020. About Gilead Sciences. Gilead Sciences, Inc.

Science 52

Science Therapies Virus Disease 52

PLOS: DNA Science

JUNE 26, 2025

DNA Science has covered eDNA clinging to minerals to reconstruct a 2-million-year-old ecosystem from northern Greenland in the throes of climate change, and in the air surrounding two European zoos. The approach can detect emerging infectious diseases like new flu or COVID variants, as well as track allergens.

DNA 56

DNA Bioethics Science Laboratories 56

The Pharma Data

MAY 5, 2022

In animal studies that mimic human exposures, an investigational COVID vaccine designed to be taken orally not only protects the host, but also decreases the airborne spread of the virus to other close contacts. The findings are published today in the journal Science Translational Medicine. Science Translational Medicine, 2022.

Vaccine 52

Vaccine Disease Virus Science 52

PLOS: DNA Science

FEBRUARY 8, 2024

Already, engineered probiotics have been used to treat metabolic disorders like inflammatory bowel disease and obesity, single-gene conditions like PKU, and bacterial infections common in people who have cystic fibrosis. Or, add genes to arm a host species to resist a specific infectious disease. Probiotics are an enticing target.

Immune Response 97

Immune Response DNA Engineering Virus 97

Broad Institute

DECEMBER 13, 2023

Related news Researchers map brain cell changes in Alzheimer’s disease Courtesy of the Chen and Macosko labs. The researchers also discovered clues about cellular function and the potential roles of brain structures in disease. Courtesy of the Chen and Macosko labs. Our results underscore the need to study them more deeply.”

DNA 140

DNA Virus Research Engineering 140

Alta Sciences

JULY 25, 2024

Top 10 Life Science Resources for Summer 2024 pmjackson Thu, 07/25/2024 - 14:44 There’s a lot of life science content out there, which is why we’ve curated a selection of our expert insights, tips, case studies, and scientific and regulatory information for your convenience. Tags Science and Health Weight 16 the UK, or the EU.

Science 52

Science Clinical Trials Clinical Pharmacology FDA 52

PerkinElmer

MAY 28, 2020

Time is of the essence when it comes to the development of a vaccine for the novel infectious disease in our current pandemic. Unfortunately, the road towards treatment can be time-consuming, especially when utilizing assays with live virus.

Vaccine 52

Vaccine Disease Virus Small Molecule 52

Broad Institute

MAY 30, 2023

By Andrea Tamayo May 30, 2023 Credit: Allison Dougherty, Broad Communications Isabella Teixeira-Soldano studies single cells to better understand disease progression. Isabella Teixeira-Soldano began her career in science sifting through mud. What inspires you to keep working in your field?

Research 89

Research Medical Schools Doctors Science 89

Drug Target Review

SEPTEMBER 28, 2023

They had the science and the technology but not the business model. They needed reference materials for the disease in order to develop and validate diagnostic tests. For security reasons, at the time COVID-19 had to be grown in BSL-3 labs, which can be dangerous because they were handling the live virus.

DNA 116

DNA Organic Chemistry Science Virus 116

Broad Institute

AUGUST 31, 2023

Related News Next generation prime editing systems move closer to possible therapeutic applications New CRISPR genome editing system offers a wide range of versatility in human cells Prime editing technologies allow scientists to precisely edit the genome in a variety of ways and could one day be used to treat genetic diseases.

DNA 145

DNA RNA Engineering Laboratories 145

The Pharma Data

JANUARY 31, 2021

–( BUSINESS WIRE )– Gilead Sciences, Inc. While HIV treatment has advanced dramatically over the past three decades, people living with HIV still face a lifetime of therapy,” said Diana Brainard, MD, Senior Vice President, Virology Therapeutic Area, Gilead Sciences. 1, 2021 11:00 UTC. FOSTER CITY, Calif. &

Vaccine 52

Vaccine Science Clinical Trials Licensing 52

The Pharma Data

MAY 19, 2023

HIGH SCHOOL SCIENTISTS AND ENGINEERS WIN NEARLY $9 MILLION AT THE REGENERON INTERNATIONAL SCIENCE AND ENGINEERING FAIR 2023 Regeneron Pharmaceuticals, Inc. Other top prizes went to projects in the fields of computational biology, animal sciences and neurobiology.

Engineering 52

Engineering International Science Virus 52

The Pharma Data

MARCH 9, 2022

Novartis today announced a license option agreement with Voyager Therapeutics, a gene therapy company focused on next-generation adeno-associated virus (AAV) technologies, for three capsids to use in potential gene therapies for neurological diseases, with options to access capsids for two other targets. About Novartis.

Licensing 52

Licensing Licensing Therapies Disease 52

Codon

OCTOBER 13, 2024

” From their first intrepid steps into the fields, GM crops have become a scapegoat for distrust in science and its overextension into formerly “unadulterated” products. One of these is “citrus canker,” a bacterial disease that causes the fruits to develop necrotic lesions. Yields were devastated.

Engineering 108

Engineering Virus Production DNA 108

The Pharma Data

DECEMBER 15, 2020

A healthy immune system defends the body against disease and other conditions. Autoimmune disease impacts different parts of the body, weakening functionality. Researchers are aware of more than 80 diseases that occur when the immune system attacks the body’s own organs, tissues and cells. It may be life-threatening.

Disease 52

Disease Clinical Trials Small Molecule Trials 52

PLOS: DNA Science

JUNE 1, 2023

This DNA Science post from 2018 traces the history of the efforts. Peter Marinkovich, MD, director of the Blistering Disease Clinic at Stanford Health Care, calls DEB a devastating disease. A dominant form – DDEB – is less severe, blistering the hands, feet, knees, and elbows. Primary investigator M.

FDA Approval 52

FDA Approval Therapies FDA Disease 52

The Pharma Data

APRIL 26, 2022

NYSE: PFE) today reported positive Phase 2 pediatric data for their Lyme disease vaccine candidate, VLA15. About VLA15 VLA15 is the only Lyme disease vaccine candidate currently in clinical development. The medical need for vaccination against Lyme disease is steadily increasing as the geographic footprint of the disease widens7.

Vaccine 52

Vaccine Disease Protein Expression Trials 52

The Pharma Data

JANUARY 6, 2021

A Novel Ebola Virus VP40 Matrix Protein-Based Screening for Identification of Novel Candidate Medical Countermeasures.’ The published study results showed that OYA1 was “highly effective” in reducing the spread of Ebola Virus infection in laboratory tests with the live Ebola virus carried out by NIAID.

Virus 40

Virus Clinical Trials Government Laboratories 40

The Pharma Data

MARCH 8, 2021

The companies today reported findings on one secondary objective from the Phase 2a study, showing a reduction in time (days) to negativity of infectious virus isolation in nasopharyngeal swabs from participants with symptomatic SARS-CoV-2 infection, as determined by isolation in Vero cell line culture. About Molnupiravir.

Trials 69

Trials Virus RNA Research Laboratories 69

Drug Target Review

NOVEMBER 24, 2023

The use of nanoparticles, which are around the size of a virus particle, is a very promising delivery method for overcoming chemotherapy issues. 1 Dr Ninh (Irene) La-Beck, from the Department of Immunotherapeutics and Biotechnology at the Texas Tech University Health Sciences Center (TTUHSC) Jerry H.

Immune Response 111

Immune Response Pharmacy Treatment Virus 111

SCIENMAG: Medicine & Health

OCTOBER 18, 2023

This study is conducted by the Jiangsu Provincial Center for Disease Control and Prevention, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, State Key Laboratory of Vaccines for Infectious Diseases of Xiamen University, China National Institutes for Food and Drug Control, and Xiamen Innovax Biotech Company.

Vaccine 52

Vaccine Laboratories Virus Science 52

The Pharma Data

OCTOBER 6, 2021

1] This research builds on Johnson & Johnson’s work to advance science against emerging and entrenched global public health threats. We are hopeful that this early-stage science can ultimately translate into a meaningful difference for at risk communities. Janssen is now moving its dengue program into clinical development.

Virus 52

Virus Clinical Development Science Disease 52

Broad Institute

SEPTEMBER 26, 2024

Their dedication, enthusiasm for science, love, and support made this experience unique. Lastly, BSRP is about science, leadership, community, and, most importantly, change. I cannot wait to see all the changes we will make in the world and how we will use all the lessons to transform the science community.

Science 52

Science Virus Disease Research 52

Nvidia Developer: Drug Discovery

OCTOBER 5, 2021

Recently published in the Proceedings of the National Academy of Sciences , the research develops a deep learning model that determines the best drug combinations for fighting the virus, despite having relatively limited data. Read the full article in the Proceedings of the National Academy of Sciences >> Read more >>

Drugs 52

Drugs Virus Science Disease 52

NIH Director's Blog: Drug Development

OCTOBER 27, 2020

Science, 2020 One way to fight COVID-19 is with drugs that directly target SARS-CoV-2, the novel coronavirus that causes the disease. Another promising strategy is drugs that target the proteins within human cells that the virus needs to infect, multiply, and spread. Credit: DE Gordon et al., Gordon DE et al.

Drug Development 52

Drug Development Drugs Virus Science 52

Drug Target Review

OCTOBER 25, 2023

Dr Tal, Assistant Professor of Obstetrics, Gynaecology and Reproductive Sciences at Yale School of Medicine and senior author of the study, said: “Previous findings imply there is an important function for CXCR4 in pregnancy.” Many of these adaptations happen within the decidua, tissue that surrounds and interacts with the placenta.

Treatment 106

Treatment Virus Research Science 106

NIOSH Science Blog: Drugs

FEBRUARY 3, 2023

Air filtration units were widely used during large wildfire outbreaks in the western United States,[1] and their use surged nationwide during the COVID-19 pandemic as a way to reduce exposure to aerosols containing the SARS-CoV-2 virus.

Virus 97

Virus Production Engineering Disease 97

Broad Institute

SEPTEMBER 30, 2024

Today, about a third of Broad’s Terra users are from the public health workforce; in the US, 76 state and local public health labs use the platform for preventing and monitoring infectious disease spread in their communities. This was true in the US and all the more in the Global South, where the burden of infectious disease is the highest.

Bioinformatics 101

Bioinformatics Disease Virus Engineering 101

The Pharma Data

AUGUST 1, 2021

In a sample of over 400 older adults in Argentina who had recovered from COVID-19, more than 60% displayed some degree of cognitive impairment, a researcher from The University of Texas Health Science Center at San Antonio reported July 29 at the Alzheimer’s Association International Conference. That is worrisome,” Dr. de Erausquin said.

Virus 52

Virus International Science Disease 52

NIH Director's Blog: Drug Development

APRIL 2, 2020

Science, 2020. With so much information swirling around these days about the coronavirus disease 2019 (COVID-19) pandemic, it would be easy to miss one of the most interesting and significant basic science reports of the past few weeks. ACE2 is the receptor that the virus uses to gain entry. Credit: Adapted from Yan R.,

Drug Development 52

Drug Development Drugs Science Medical Schools 52

The Pharma Data

OCTOBER 28, 2020

In the overall patient group with detectable virus at baseline, the average daily reduction in viral load through day 7 was a 0.36 About REGN-COV2 REGN-COV2 is a combination of two monoclonal antibodies (REGN10933 and REGN10987) and was designed specifically to block infectivity of SARS-CoV-2, the virus that causes COVID-19.

Virus 40

Virus Trials Clinical Trials Production 40

The Pharma Data

AUGUST 11, 2020

Gilead Sciences has asked the FDA to approve its drug remdesivir to treat COVID-19 patients. It has not received general approval to treat the virus in the US, but has in several European countries and Japan. It has not received general approval to treat the virus in the US, but has in several European countries and Japan.

FDA Approval 52

FDA Approval FDA Government Virus 52