Codon

JULY 10, 2025

The event hosts will provide snacks and drinks, and the winning teams will get signed copies of our DNA books and free hats. Stories We Want to Publish Bottlenecks in Tree Engineering In 1903, John Krusback, the president of a local state bank in Wisconsin, decided that he was going to grow a chair. Please RSVP to join.

Engineering

Drug Target Review

SEPTEMBER 28, 2023

After some time in that role and launching several products, I received a call from Bill Banyai and Bill Peck, or ‘The Bills’ as we call them, who were building a company around technology that creates DNA by ‘writing’ it on a silicon chip. Because I was put into the highest tier, I was automatically mapped to the engineering track.

DNA

DrugBank

MARCH 28, 2024

Space biosciences are on the verge of becoming one of the largest total addressable markets to ever exist, opening up vast opportunities for economic growth and scientific discovery.    In the realm of space exploration, one critical yet often overlooked aspect is the impact of space conditions on human health.

DNA

Codon

DECEMBER 10, 2023

A zoologist, ecologist, and protein engineer all call themselves “biologists,” but rarely attend the same conferences. This last variable could be just about anything; there are proteins that bind to other proteins (like antibodies), cut other proteins (proteases), or bind DNA (transcription factors).

Protein Expression

Codon

OCTOBER 13, 2024

Genetic engineering in the medicine cabinet is one thing; allowing it at the dinner table is another. The chefs at Farma know that by embracing food technologies such as recombinant DNA, precision fermentation, and cell culture, food can become more nutritious and better for the planet. At the dining table. More are still unfolding.

Engineering

Codon

DECEMBER 10, 2023

A zoologist, ecologist, and protein engineer all call themselves “biologists,” but rarely attend the same conferences. This last variable could be just about anything; there are proteins that bind to other proteins (like antibodies), cut other proteins (proteases), or bind DNA (transcription factors).

Protein Expression

Drug Target Review

JULY 5, 2023

The first critical decision is whether to access one of the commercially available host cell line, vector and CLD platforms on the market, or to develop a novel, proprietary system in house. A potential future for host cell lines There have been many recent advances in cell line engineering technologies and our understanding of CHO cells.

Engineering

DrugBank

OCTOBER 17, 2024

Data Science in Lead Optimization and Drug Design Data science accelerates the lead optimization and drug design process, transforming how molecules are engineered for therapeutic applications. These complex molecules require precise engineering to ensure optimal efficacy and safety.

Drug Development

Drug Target Review

JULY 31, 2023

For my PhD project, I chose an advisor who worked on DNA and I started working with her on the physical properties of DNA. I worked with Jackie Barton in the early days of what’s now called DNA-mediated electron transfer. I went to Genentech and postdoc-ed for Jim Wells in protein engineering.

DNA

The Pharma Data

JANUARY 31, 2021

(NASDAQ: ILMN), the global leader in DNA sequencing and array-based technologies, and Sequoia Capital China , a leading investment firm, today announced a collaboration to catalyze the startup ecosystem in China with the launch of the Sequoia Capital China Intelligent Healthcare Genomics Incubator, Powered by Illumina.

DNA

The Pharma Data

SEPTEMBER 11, 2021

By leveraging our unique ability to manufacture DNA at scale, we can construct proprietary antibody libraries precisely designed to match sequences that occur in the human body. The core of the platform is a proprietary technology that pioneers a new method of manufacturing synthetic DNA by “writing” DNA on a silicon chip.

DNA

Broad Institute

JULY 11, 2024

Drugs that block mutated IDH1 (mIDH1) have recently come onto the market and effectively slow tumor growth, but the exact mechanism at work to stall tumors is still unclear. Reporting in Science , researchers at Massachusetts General Hospital and the Broad Institute of MIT and Harvard have made a surprising discovery about these drugs.

Treatment

Drug Target Review

DECEMBER 5, 2024

2 Structure and function of AAV capsids in gene therapy Wild-type AAV is composed of a protein shell (capsid) that contains a single-stranded DNA genome encoding proteins involved in viral replication, structure and assembly. Dr Chelsea B Pratt is the Biopharma Segment Marketing Manager at Bio-Rad Laboratories.

Therapies

The Open Targets Blog

APRIL 25, 2023

Although the estate was undoubtedly pretty, the Hall had seen better days and was rather dominated by a 1950s building that provided laboratories for the light engineering company that had owned the site. ranging from university academics through engineers and clerical staff to the military. The same went for analysis tools.

DNA

The Pharma Data

DECEMBER 14, 2020

The global GBM treatment market is projected to reach $3.3 representing the largest market. engine along with algorithms tuned to predict BBB permeability played an important role in helping determine which CNS cancers and which genomically-defined subtypes of CNS cancer should be prioritized for development. .

Clinical Trials

The Pharma Data

OCTOBER 19, 2020

The company’s suite of market-leading molecular profiling offerings assesses DNA, RNA and proteins to reveal a molecular blueprint that helps physicians and cancer patients make more precise and personalized treatment decisions. Europe , Asia and other international markets. Caris provides services throughout the U.S.,

Clinical Trials

Alta Sciences

APRIL 17, 2024

Several viral vectors are being used currently, in addition to non-viral vectors, such as oligonucleotides, naked DNA, and lipoplexes and polyplexes. Fifteen oligonucleotides have so far received market authorization in different countries, and several others are being test in clinical Phase I to III trials. Asia, and Europe.

Drug Development

Nvidia Developer: Drug Discovery

MARCH 21, 2023

Creating new drug candidates is a heroic endeavor, often taking over 10 years to bring a drug to market. Creating new drug candidates is a heroic endeavor, often taking over 10 years to bring a drug to market. New supercomputing-scale large language models (LLMs).

Small Molecule

The Pharma Data

NOVEMBER 27, 2020

The PRV can be redeemed to receive priority review for any subsequent marketing application or sold or transferred to other companies for their programs. With this approval, the FDA issued a Rare Pediatric Disease Priority Review Voucher (PRV) to Rhythm.

FDA Approval

Agency IQ

APRIL 12, 2024

Additionally, six of these comments came from the same organization (Integrated DNA Technologies). The International Society for Pharmaceutical Engineering (ISPE) took a more nuanced approach, requesting that the language be tweaked to indicate that multiple assays are often optional. Should potency assurance plans be submitted?

Production

Codon

JULY 17, 2024

He’s an educator, molecular florist, and founder at Binomica Labs , a small biology research group focusing on providing an alternative to “exposure-driven and marketing-centric research.” Years later, when I attended university, I stumbled upon plant genetic engineering. It changed my entire perspective on flowers.

Laboratories

Drug Target Review

OCTOBER 26, 2023

Genome engineering and gene therapies that manipulate DNA sequences in cells have driven a biotechnological revolution over the past decade. The limitations of natural AAV serotypes in meeting all clinical needs has spurred growing interest in AI-driven AAV engineering approaches. His mentorship produced numerous publications.

Engineering

Codon

FEBRUARY 13, 2024

Some algorithms simply look for important similarities between phage and bacterial DNA sequences, a signal of the extensive gene-swapping that goes on when a particular virus and bacteria have shared history. Middle and Right) Once a bacteriophage lands on a cell, it injects its DNA through a tube (purple) into the unwilling host.

Therapies

PLOS: DNA Science

JUNE 13, 2024

Through graphics and five main points, Chan countered the wet market scenario of the pandemic’s beginnings. Experiments at the Wuhan facility were done at the lowest two of the four standard biosafety levels, which were established at the dawn of recombinant DNA research in the 1970s. c) in a “wet market?”

Virus

Codon

APRIL 19, 2023

To combat these threats, genetic engineers are making bananas that fend off fungi or ripen slower than natural varieties. In 2016, her team demonstrated that, by adding short snippets of DNA or RNA — which can target and “shut down” the MaMADS regulatory proteins — to bananas, it is possible to slow their ripening.

DNA

Codon

APRIL 19, 2023

To combat these threats, genetic engineers are making bananas that fend off fungi or ripen slower than natural varieties. In 2016, her team demonstrated that, by adding short snippets of DNA or RNA — which can target and “shut down” the MaMADS regulatory proteins — to bananas, it is possible to slow their ripening.

DNA

Codon

APRIL 30, 2023

Read more at Nature Biotechnology ( Similar paper at Nature Biomedical Engineering.) But now, their engineered brethren can live about 82 percent longer. But now, their engineered brethren can live about 82 percent longer. Engineered yeast live longer than their “normal” brethren. From Zhang et al.

Vaccine

Codon

APRIL 30, 2023

Read more at Nature Biotechnology ( Similar paper at Nature Biomedical Engineering.) But now, their engineered brethren can live about 82 percent longer. But now, their engineered brethren can live about 82 percent longer. Engineered yeast live longer than their “normal” brethren. From Zhang et al.

Vaccine

Codon

MARCH 20, 2023

🧪 Papers AI + Bio Protein-specific signal peptides for mammalian vector engineering. Biological Engineering Generation of functional oocytes from male mice in vitro. Marine biofilm engineered to produce current in response to small molecules. Marine biofilm engineered to produce current in response to small molecules.

Virus

Drug Target Review

APRIL 16, 2024

By delivering radiation directly to the tumour cells, RLT can induce DNA damage, leading to cell death and tumour regression. Key advantages of mAbs over peptides and small molecules are: High Specificity: mAbs can be engineered to bind specifically to a particular target antigen with high affinity.

Small Molecule

The Pharma Data

AUGUST 3, 2021

. – Second-quarter 2021 operating expenses increased 18 percent, driven primarily by higher research and development investments for late-stage assets, as well as higher relative marketing and selling expenses due to pandemic-related spending reductions in 2020. – Second-quarter 2021 earnings per share (EPS) decreased to $1.53

Production

PLOS: DNA Science

SEPTEMBER 21, 2023

I interviewed him for Genetic Engineering News , where I covered gene amplification – a field that began with Mullis’s PCR. What steps should researchers take when attempting to acquire DNA samples from modern descendants? The post The Festival of Genomics and Biodata 2023 Comes to Boston appeared first on DNA Science.

DNA

Codon

JULY 27, 2023

They’ve just finished sequencing the patient’s genome, but they don’t have “DNA sorting” software. billion units of DNA code are transcribed into more than a hundred volumes, each a thousand pages long, in type so small as to be barely legible.” At least, that’s what every textbook says.

Therapies

Codon

JULY 27, 2023

They’ve just finished sequencing the patient’s genome, but they don’t have “DNA sorting” software. billion units of DNA code are transcribed into more than a hundred volumes, each a thousand pages long, in type so small as to be barely legible.” At least, that’s what every textbook says.

Therapies

PLOS: DNA Science

OCTOBER 12, 2023

In addition to high cost and small markets, patient responses haven’t been predictable. million DNA bases. The DMD gene therapy delivers a shortened version of the dystrophin gene, just 4,558 DNA bases. appeared first on DNA Science. The implicated gene is the largest in a human genome, with 2.2

Therapies

DrugBank

FEBRUARY 26, 2025

Targeting Novel Bacterial Pathways Traditional antibiotics often target essential bacterial processes such as cell wall synthesis or DNA replication. Advances in genetic engineering have enabled researchers to enhance bacteriophage efficacy and overcome bacterial resistance mechanisms.

Therapies

Codon

MARCH 24, 2024

Novo Nordisk’s market capitalization ($442B) is already larger than the GDP of Denmark ( $404B ), the country where the company is headquartered. The market for semaglutide-based products is projected to swell to $71B in less than a decade. market with Wegovy will, by 2030, require about one million liters of production capacity.

Vaccine