Drug Discovery World

MAY 3, 2024

News round-up for 29 April – 3 May by DDW Multimedia Editor Megan Thomas. The ongoing innovation and development in the drug discovery sector relies on a number of moving parts, one of which is financial support and backing. Whether it is successful seed funding or dedicated investment, this money enables scientists to produce top-quality research which will in turn result in discoveries and drugs that help tackle disease and areas of unmet need.

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Science Daily: Pharmacology News

MAY 3, 2024

A stretchy electronic skin could equip robots and other devices with the same softness and touch sensitivity as human skin, opening up new possibilities to perform tasks that require a great deal of precision and control of force.

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Drug Discovery World

MAY 3, 2024

SynOx Therapeutics has closed a $75m Series B financing round, which will be used to generate registrational Phase III clinical and CMC data for emactuzumab, the company’s potentially best-in-class CSF-1(R) inhibiting monoclonal antibody (mAb) for the treatment of tenosynovial giant cell tumour (TGCT). TGCT is a type of tumour that affects the soft tissue lining of joints and tendons and is a highly debilitating disease often impacting large, important joints such as the knee, hip and ankle.

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Science Daily: Pharmacology News

MAY 3, 2024

Researchers uncovered compelling evidence that Earth's magnetic field was in a highly unusual state when the macroscopic animals of the Ediacaran Period -- 635 to 541 million years ago -- diversified and thrived. Their study raises the question of whether these fluctuations in Earth's ancient magnetic field led to shifts in oxygen levels that may have been crucial to the proliferation of life forms millions of years ago.

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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

Clinical Trials

Drug Discovery World

MAY 3, 2024

ExoXpert has partnered with Neucore Bio to leverage ExoXpert’s platform for evaluation of advanced exosome loading. Under the agreement, ExoXpert will test and optimise efficient loading of proprietary payloads into exosomes as part of Neucore’s Fibroblast EV Engineering (FiXE(R)) discovery platform. “This collaboration is an important step in the loading validation and application of our FiXE platform using advanced, non-viral exosomes for therapeutic delivery,” said Dr Kenneth

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BioPharma Drive: Drug Pricing

MAY 3, 2024

Newly disclosed Phase 3 results presented Friday match findings the biotech disclosed last year, while offering a more comprehensive look at how its drug stacks up to rival therapies.

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BioPharma Drive: Drug Pricing

MAY 3, 2024

The company said data for its Wegovy competitor was promising enough to move the drug into late-stage testing, triggering a stock jump that added billions to Amgen’s market value.

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Science Daily: Pharmacology News

MAY 3, 2024

New research suggests that countries' current plans to remove CO2 from the atmosphere will not be enough to comply with the 1.5 C warming limit set out under the Paris Agreement.

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Drugs.com

MAY 3, 2024

FRIDAY, May 3, 2024 -- People in homes with gas or propane stoves regularly breathe in unhealthy levels of nitrogen dioxide, a new study says.Typical use of these stoves increases exposure to nitrogen dioxide (NO2) by an estimated 4 parts per.

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Science Daily: Pharmacology News

MAY 3, 2024

Heavy pooling meltwater can fracture ice, potentially leading to ice shelf collapse.

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Clinical Trials

Drugs.com

MAY 3, 2024

FRIDAY, May 3, 2024 -- Folks undergoing cardiac catheterization procedures to diagnose heart problems may be able to safely skip the traditional pre-op fasting that's now the norm, new research shows.“Just as our techniques and technology for.

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BioPharma Drive: Drug Pricing

MAY 3, 2024

Conversations at this year's J.P. Morgan Healthcare Conference led to a $1 billion buyout that Mariana's CEO described as a "perfect marriage.

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Drugs.com

MAY 3, 2024

FRIDAY, May 3, 2024 -- Advanced liver cirrhosis can push levels of ammonia in the blood to hazardous levels, but skipping meat at mealtime can help reverse that, new research shows.

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Agency IQ

MAY 3, 2024

BY WALKER LIVINGSTON, ESQ In this returning feature, AgencyIQ looks at public data to determine what the EPA is planning to do in the month ahead, including deadlines, meetings, events, planned regulations, comment periods, and more. Late May will mark the beginning of the period where agency regulations can be subject to a Congressional Review Act (CRA) lookback resolution when the next Congress is seated in January.

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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

Clinical Trials

Drugs.com

MAY 3, 2024

FRIDAY, May 3, 2024 -- Primates are capable of tending to wounds using medicinal plants, a new case report says.

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Agency IQ

MAY 3, 2024

BY LAURA DIANGELO, MPH The Covid-19 pandemic highlighted some gaps in existing policy for how tests and diagnostics are regulated and deployed in emergency situations. The FDA recently issued a new rule to overhaul its enforcement policies for laboratory developed tests (LDTs), and has also issued two accompanying guidance documents outlining implications and new expectations for emergency response and what an emergency-related enforcement discretion would potentially look like going forward.

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Drugs.com

MAY 3, 2024

FRIDAY, May 3, 2024 -- Doctors in Texas are describing the only known human case of H5N1 avian flu connected to the ongoing outbreak of the disease in dairy cows.Bird flu in humans remains extremely rare, but in the hundreds of cases documented.

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Agency IQ

MAY 3, 2024

BY SCOTT STEPHENS, MPA Welcome to AgencyIQ’s monthly roundup of EU chemical sector activities. This recurring feature compiles information from across EU agencies and institutions to deliver an overview of chemicals-related regulatory actions likely to happen in the month ahead, including planned legislation, consultations, webinars, meetings, and more.

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Regulations 59

Perficient: Drug Development

MAY 3, 2024

In the competitive world of B2C commerce, fostering customer loyalty is paramount. Salesforce Commerce Cloud (SFCC) provides a robust platform that goes beyond transactions, offering a powerful toolset to orchestrate the entire lead-to-loyalty journey. Here’s how SFCC empowers businesses to build lasting customer relationships: Targeted Acquisition Strategies: From the moment a customer lands on your site, leverage their data to create a personalized experience.

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Agency IQ

MAY 3, 2024

BY ALEXANDER GAFFNEY, MS, RAC In this ongoing feature, AgencyIQ looks at public data to determine what the FDA is likely to do in the months ahead, including key deadlines, meetings, events, planned regulations, comment periods and more. The goal: To allow regulatory professionals to better anticipate and prepare for upcoming events and catalysts. Fill out the form to read the full article.

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Drug Patent Watch

MAY 3, 2024

Annual Drug Patent Expirations for MYRBETRIQ+GRANULES Myrbetriq Granules is a drug marketed by Apgdi and is included in one NDA. It is available from one supplier.

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Drugs.com

MAY 3, 2024

FRIDAY, May 3, 2024 -- Peripheral artery disease (PAD) involves a debilitating narrowing of arteries in the legs, and the National Institutes of Health estimates that 1 in every 20 Americans over 50 is affected.Research into best treatments for.

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Drug Patent Watch

MAY 3, 2024

Annual Drug Patent Expirations for OXBRYTA Oxbryta is a drug marketed by Global Blood Theraps and is included in two NDAs. It is available from one supplier.

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Agency IQ

MAY 3, 2024

BY CHELSEY MCINTYRE, PHARMD , KIRSTEN MESSMER, PHD, RAC , COREY JASEPH, MS, RAC , KARI OAKES , SEBASTIAN GODOY, MPH In this recurring feature, AgencyIQ, through public data and previous analysis, determines what European medicine and device regulators will likely do in the month ahead, including key deadlines, meetings, events, planned regulations, comment periods, and more.

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Drug Patent Watch

MAY 3, 2024

Annual Drug Patent Expirations for PONVORY Ponvory is a drug marketed by Janssen Pharms and is included in one NDA. It is available from one supplier.

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Perficient: Drug Development

MAY 3, 2024

Did you know you can create an RSS feed in AEM (Adobe Experience Manager) for external applications like Eloqua? While AEM provides out-of-the-box functionality for RSS feeds, customizing them may require additional steps. Below you’ll find several options for creating RSS feeds in AEM along with steps for creating one using HTL. 3 Options to Create an RSS Feed in AEM Override Default JSP Functionality (JSP Approach) Customize the JSP code to tailor the RSS feed according to your requirem

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Drug Patent Watch

MAY 3, 2024

Annual Drug Patent Expirations for MYRBETRIQ Myrbetriq is a drug marketed by Apgdi and is included in two NDAs. It is available from three suppliers.

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Drugs.com

MAY 3, 2024

FRIDAY, May 3, 2024 -- Artificial intelligence might be able to identify patients who have rare diseases years earlier than they would typically be diagnosed, a new study says.A newly developed AI program was able to successfully identify people at.

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Drug Patent Watch

MAY 3, 2024

Annual Drug Patent Expirations for SUNOSI Sunosi is a drug marketed by Axsome Malta and is included in one NDA. It is available from one supplier.

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Drugs.com

MAY 3, 2024

FRIDAY, May 3, 2024 -- Pre-kindergarten programs have long been considered an early ticket to future success for children.But the evidence is much more mixed than one might think regarding the longer-term effectiveness of preschool programs, a new.

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thought leadership

MAY 3, 2024

In the highly regulated pharmaceutical industry, ensuring the safety, quality, and efficacy of medicinal products is paramount. One crucial aspect of this assurance lies in the oversight provided by Qualified Persons (QPs) and the audits they conduct. Particularly, within the European Union (EU) and the United Kingdom (UK), QP audits play a pivotal role in maintaining compliance with stringent regulatory standards.

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Drug Patent Watch

MAY 3, 2024

Annual Drug Patent Expirations for CEQUA Cequa is a drug marketed by Sun Pharm and is included in one NDA. It is available from one supplier.

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ASPET

MAY 3, 2024

The prefrontal cortex (PFC) has justifiably become a significant focus of chronic pain research. Collectively, decades of rodent and human research have provided strong rationale for studying the dysfunction of the PFC as a contributing factor in the development and persistence of chronic pain and as a key supraspinal mechanism for pain-induced comorbidities such as anxiety, depression and cognitive decline.

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Agency IQ

MAY 3, 2024

What we expect the EPA to do in May 2024 In this returning feature, AgencyIQ looks at public data to determine what the EPA is planning to do in the month ahead, including deadlines, meetings, events, planned regulations, comment periods, and more. BY WALKER LIVINGSTON, ESQ | APR 25, 2024 5:24 PM CDT What we expect to be talking about in May A continued surge in regulatory action.

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